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By Jane

Research Question: How can previous knowledge on iPSCs’ production of sex cells be applied to primates, to help us understand more about same sex reproduction?

Argument: There is not enough research on using iPSCs for same-sex reproduction. However, there is evidence and previous experimentation that shows the method of using iPSCs to produce sperm do work. With more research and experiments on primates, we can understand more.

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By Clara

Research Question: How can a drug be developed to counteract the over-pruning effect of the C4 gene that causes schizophrenia?

Argument: Current treatment for schizophrenia only focus on relieving the symptoms instead of targeting the underlying cause of the disease. The greatest risk factor for the C4 gene

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By: Jonathan

Research question: How can lengthen telomeres

Argument: So that cloning animals such as cows would be useful. Having  telemeres that were not lengthened would make the lives of the cows shorten because not enough white blood cells are created. They can get viruses and if we eat them, we can get sick

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By Kevin
Research Question: How can de-extinct the SMILODON?

Argument: We can take the DNA of the SMILODON,

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By Aaron
Research Question: How does serotonin affects anorexia?

Argument: Nobody is researching on genetics of anorexia, because they think that it is an environment thingy

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Research Question: Is Bovine Pituitary Extract (BPE) safe and effective

Argument: Organizations recommend this treatment to patients, but this treatment can not be put into action without scientific studies and evidence that proves that the treatment is safe. (Pretty much more research is needed)

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by: Corinne

Research Question: Can patients with diabetes be cured using stem cells in the next several years?

Argument: There is no cure for diabetes. using stem cells on humans will make the patient no longer have to worry about what they are eating and have insulin injections everyday, or prick their fingers.

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by Jamie

Research Question: How can we get SCN1A gene to function?

Argument: mutated SCN1A gene causes  Dravet Syndrome and the death rate before 12 months is 30% and there isn't enough research on the gene to cure Dravet Syndrome (revert the mutation) so there has to be more research done on this certain gene (SCN1A).

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By Ashley
Research Question: How can we find a substitution to chromosome 21

Argument: A lot of people think Alzheimer is only a brain related disease, but it could also be effected by the heart, and other parts of the body.

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By Angela

Research Question: How can we use IPS cells to create a cure for patients that have ALS?

Argument: There are temporary solutions and no cure for people with ALS. The solution given from doctors are pills and only increases the life span by a couple of months. This is not as effective.

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-Dennis

Artificially produce human organs through usage of stem cells (improvements)

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by Evan
Research Question: Can we find more cost efficient technology as a replacement to CRIPSR?

Argument: CRISPR augments genes, but it requires a lot of money (base: 6,500 USD). The tech is very effective and very good in general, but cost is the main problem.

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by Eddie
research Question: how do we increase healing speed for external skin trauma

reasons: save lives

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By Kristen
How can we make the cost cheaper?

Build several clinics with people who have knowledge of IVF and CRISPR. Supply and Demand, when more people do it, it will be cheaper.

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by Ash

Research Question: Can we create a genetically modified cannabis string that will be more medically effective for seizure reduction and parkinson's?

Argument: Cannabis has multiple benefits especially to treat seizures, however there has been no research to prove this. If we were to create a genetically modified cannabis and get it approved by the FDA , we could make this medicine more accessible to people with parkinson's and other seizural diseases.

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by Cher

Gap: cas9 protein always cuts the wrong target

Argument: If Cas9 does not cut target, it causes a mutation. Try to put mutations next the target on each sides so that Cas9 can only cut the target.

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By Vanessa

Different genes and proteins effect depression in different people.

Argument- Dopamine and serotonin make you happier, and everyone has it in their brains. By combining dopamine and serotonin a medicine could be made that will make people happier (and cure depression). The only problem is that dopamine and serotonin are drugs, so people might get addicted

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by Austin

Research Question: Can we find a better modified BT for GM corn?

Argument: Currently, BT is causing GM corn allergies and is supposedly causing corn to be low on nutrition.

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Research Question: How can we clone healthier cows?

Argument: Now, cows that are cloned require three cows. One is to have one of it's nucleus extracted and inserted into another cows egg cell. The egg cell with a different nucleus in it is then injected into another cow but that cow has a chance to reject the egg cell and the baby will die. June has an idea to retrieve the egg cell from the cow giving birth to the clone to make sure that the egg does not get rejected.

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by DK Seo
Research Question: How can we make a more efficient replacement for a cas9 protein, so that we could modify more and specific genes.

Argument: CRISPR might be the cheapest way to modify DNA, however it is not the best at cutting specific genes, or a big chunk of DNA.

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by Siming

Research Question: How can we improve the success rate and cost of producing pluripotent STEM cells?

Argument: Currently, the success rate of creating these STEM cells is around 0.1%, and it is very expensive because the process is very complicated and required many skin cells from the participant.

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by Daniel Lin
Research Question: Will gene therapy work for PKU patients?

Argument: The diet for people with this disease is too expensive and not good for the person.

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By Claire

Research question: How can we move the technology to modify genes with animals to plants.

Argument: the success rate in animals is very low, cloning is a problem for animals, but plants are easier to clone.

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Research Question: How can we make the drugs that treat sickle cell disease cheaper and have less side effects?
Argument: The treatment for sickle cell disease is expensive, and often causes side effects like body pain and dizziness, so a cheaper drug with less side effects needs to be developed to more successfully treat the disease.

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by elsie

How to cure synaptic pruning with anti psychotic drugs?

The C4 gene causes synaptic pruning to be defective by breaking connections between neurons in patients with schizophrenia. By modifying antipsychotic medication, we can improve symptoms linked to problems with synaptic pruning.

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by Richard.
how to make a drug that can improve on expression Neuregulin? to cure schizophrenia.

Neuregulin is a big contributor in the symptoms of schizophrenia, but nobody is researching increasing expression levels in the brain. Scientists are working towards doing the same thing in the heart, so perhaps the same thing can be done in the brain with more research

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By June Cho

TO BE CONTINUED...

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By Stephanie
Research Questions: How can we cure the mutated gene CNTNAP2?

Argument: The medication for Autism has many negative side effects

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By Justin
Research Question: How can we increase the amount of core blood stem cells in the umbilical efficiently to provide a treatment for acute lymphoblastic leukemia?

Argument: Umbilical cords contain core blood stem cells that can provide treatment for acute lymphoblastic leukemia. The usual treatment is very costly to conduct. As a result, core blood stem cells can improve these conditions. A drug called PGE2 can multiply and develop stem cells in the umbilical cord, allowing for a more effective and efficient treatment to be made.

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By Siwoong Lee

Research question: How can i make a cure that is cheaper than in injecting cloning factor

Argument: the current treatment is too expensive and inconvenient.

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UBER's (Justin)  future research By: Harry 

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UBER's (Justin)  future research By: Harry 

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Research question:  How can we create a IPS cell that can cure (Blank) disease effectively . (More info needed)

Argument: IPS cells can cause cancerous Tumors and take a long time to "Make". The treatment of IPS cells also cost a lot of money. (TO BE KIND OF CONTINUED)

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by Maryanne

Research question: How can we create a stimulant that has no side effects to treat ADHD?

Argument: While people are trying to treat ADHD they are struggling with other disorders from the cause of using the stimulant/

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Huntingtons disease is a disease where later on in your life your brain neurons stop working (ﾉ◕ヮ◕)ﾉ*:･ﾟ✧ after long time it will stop you from being able to do normal things such as walk or talk

research question how can we improve antibiotics (mioseline?) to make a drug that will delay the symptoms or even stop them permanently.

there is currently a drug that can delay the symptoms, but how can we make the drug more accessible and effective? this would save them life (ﾉ◕ヮ◕)ﾉ*:･ﾟ✧. and life is important and so are you! SOU GEEV MII YOOR MARNEY! $<('o'<) $<('o'<) $<('o'<)

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by michelle

research question: how can i create a drug to increase serotonin releases in the brain in OCD patients?

argument: people with OCD perform certain rituals to relive their anxiety and get a serotonin release, but with this drug, serotonin will be released naturally and will rid some of their anxiety of having to perform OCD fueled rituals

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By Timothy

How can I make a drug that would permanently cure Albanism.

Argument: There is currently no cure or treatment so victims of the disease have to avoid UV light/ extremely inconvenient.

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By Evelyn

Research Question: How can we identify more genes that cause anti-social personality disorder?

Argument: There has only been 1 gene identified up to today that plays a major factor in anti-social personality disorder. Medication targeting anti-social personality disorder can be more easily manufactured if more specific genes can be identified.