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The doctor Javier Balmis y Berenguer is better known for his contribution to humanitarian causes than for the glory of science
This military man who became the personal physician of Carlos IV convinced this King and his ministers to promote an expedition that would spread, altruistically, the smallpox vaccine throughout the globe.

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This civil and military engineer worked for the Kingdom of Spain and the Russian Empire on various projects. Commissioned by Tsar Alexander I, he designed the urban development of several Russian cities
He also designed the first continental steam engine and several hot air balloons. For Spain, he founded the first School of Civil and Canal Engineers in 1802.

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Jaume Ferrán i Clua, a doctor and bacteriologist at the end of the 19th century, developed a vaccine against cholera, with great success in its use in an epidemic in Valencia, and also discovered cures against typhus and tuberculosis.

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Created the most advanced calculator of its time, capable of direct multiplication
This calculator consisted of a metal cylinder with ten sides, each of which had a column of holes with ten other different diameters.
Verea was never interested enough in marketing the calculator.

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He was a Cantabrian civil engineer who ran the Applied Mechanics Laboratory in an outstanding way and developed the first Spanish airship, far above the rest of the European models.
He is also known for designing the first mechanical cable car and the first calculating machine.

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Isaac Peral developed the first torpedo submarine that was propelled by means of electrical energy. His ship passed technical tests, but the authorities scrapped Peral's invention, who after retiring from the Navy set about reestablishing his damaged prestige.

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Mónico Sánchez was an ingenuity that invented in 1907 a portable X-ray machine, approximately ten kilograms, used in many European and American hospitals. His invention saved many lives and placed him among the most in-demand scientists in the United States, where he went on to work as an engineer.

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Rafael Suñén invented synthetic oil from charcoal
His innovation attracted the interest of the French and British governments, but he refused
Determined that it be exploited in Spain. When the Civil War began, he was arrested by the Republican Government in Madrid and entered the Modelo prison.

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The sailor Antonio de Ulloa was the one who made platinum known to Europe, a chemical element with atomic number 78, which he found in Esmeraldas (Ecuador)
He participated in multiple scientific tasks and contributed to the Navy being an enlightened body also under the protection of Ensenada.

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In 1826, he managed to find the mineral "Thenardite", but he himself requested that the name be given to the Frenchman L. J. Thenard, who had been his teacher for three years in Paris. His generosity played against his fame.