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Syphilis is a bacterial infection that is usually spread by sexual contact. It is a sexually transmitted disease caused by the bacterium Treponema pallidum. This disease starts out as sores usually starting on the genitals, rectum, or the mouth. Syphilis can spread through the skin or through mucous membrane contact with these painless sores.

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Syphilis develops in different stages and the symptoms are also different with each stage. Sometimes the stages overlap, so the symptoms may not always occur in the same order. You could be infected with syphilis and not notice symptoms for years.

Groin: painless ulcers, sores, vaginal discharge, or wart-like growths on genitals

Skin: rashes, small bump, or ulcers

Also common: fatigue, itching, mouth ulcer, rash on the palms and soles, sore throat, swollen lymph nodes, weight loss, or rectal lining inflammation

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https://www.southernnevadahealthdistrict.org/Health-Topics/syphilis/syphilis-quick-facts/

https://www.mayoclinic.org/diseases-conditions/syphilis/symptoms-causes/syc-20351756

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Any sexually-active person can get syphilis. Syphilis can be transmitted during anal sex and oral sex, and vaginal sex. Syphilis is passed from person to person through direct contact with a syphilis sore. P&S syphilis rates in 2000 were highest among women ages 20- to 24-years-old and among men ages 25- to 29-years-old.

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Abstain or be monogamous. The only certain way to avoid syphilis is to not have (abstain from) sex. The next-best option is to have mutually monogamous sex in which both people have sex only with each other and neither partner is infected.

Use a latex condom. Condoms can reduce your risk of contracting syphilis, but only if the condom covers the syphilis sores.

Avoid recreational drugs. Misuse of alcohol or other drugs can inhibit your judgment and lead to unsafe sexual practices.

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If you are diagnosed in early stages, syphilis is easier to cure. The best treatment at all stages is penicillin, an antibiotic medication that can kill the organism that causes syphilis. If you're allergic to penicillin, your doctor may suggest another antibiotic or recommend penicillin desensitization. If you are diagnosed with primary, secondary or early-stage latent syphilis, the recommended treatment is a single injection of penicillin. If you've had syphilis for longer than a year, you may need additional doses.