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Include carbon monoxide and nitric oxide.
They exist for a short period of time because they are rapidly broken down and produce other chemicals or second messengers.

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Examples: Adenosine and adenosine triphosphate (ATP).
Adenosine acts to inhibit the release of several neurotransmitters such as acetylcholine and serotonin.
ATP is a neurotransmitter that is used to deliver energy to various parts of the body.

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Only neurotransmitter in its class. Found at numerous synapses within the nervous system, including those in the central nervous system and autonomic nervous system. It is the most important chemical messenger for motor neurons in the peripheral nervous system. It excites skeletal muscle and inhibits cardiac muscle. Involved in learning and memory.

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Multiple functions and they include modulation of psychomotor function, cardiovascular, respiratory and gastrointestinal control, sleep mechanisms, hormone secretion, body temperature, and pain. Four examples: dopamine, serotonin, adrenaline, noradrenaline.

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Two of the most commonly found amino acids in the central nervous systems of mammals are gamma-aminobutyric acid (GABA) and glutamate. GABA is the main inhibitory neurotransmitter in the central nervous system, whereas glutamate is the main excitatory neurotransmitter.

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Large-molecule transmitters. They affect the sensitivity of neurons to signals but do not themselves send signals to other neurons. Example: endorphins.