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He started behind the camera as a production assistant in the movie Analyze This. His acting debut came a year later in a short film called Tag in 1999
He wrote and directed a short film, Highs and Lows, which was presented at the South by Southwest Film Festival in 2003. In addition, for MTV he wrote, produced and starred in a pilot called The Dustin and Justin Show. He has stated that he would like to continue working behind the camera in the future. He played an important role in Gigli and Carnival Sun, before co-starring National Treasure, in the role of Riley Poole.
In 2006, Bartha had a supporting role in Failure to Launch and starred in the television series Teachers, which premiered on March 28, 2006 on NBC and was canceled May 15, 2006 due to low ratings.
In November 2007, Bartha accepted a role in High Rollers. His character attracts a young Jew to become a distributor of ecstasy. Shooting is scheduled to begin in New York in the spring of 2008. He currently lives in New York City.
In 2009 he stars in the hit comedy The Hangover as the fourth protagonist.
He currently plays David Murray on the NBC television series The New Normal.

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Edward Helms (24 January 1974, Atlanta, Georgia), better known as Ed Helms, is an American actor best known for his role as Stu Price in The Hangover and Andy Bernard in The Office (NBC). Its beginnings, however, were like correspondent of the program The Daily Show next to Jon Stewart.

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Zacharius Knight "Zach" Galifianakis (Wilkesboro, October 1, 1969) is an American actor and comedian, known for numerous roles in movies and television appearances, including his own Comedy Central Presents Special program. Initially he was not considered more than an underground comedian, but in 2009 gained considerable popularity thanks to his performance in the hit comedy The Hangover.

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Bradley Charles Cooper (Philadelphia, Pennsylvania, January 5, 1975) is an American actor and ex-model. He has appeared in films such as Failure to Launch (2006), Yes Man (2008), He's Just Not That Into You (2009), The Hangover (2009) Hangover Part III (2013), Silver Linings Playbook (2012) and American Sniper (2015). His work at Silver Linings Playbook earned him his first Oscar nomination in the Best Actor category. Cooper was nominated again in the next two years for his work on American Hustle and American Sniper.

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The Hangover is a film directed by Todd Phillips and starring Bradley Cooper, Ed Helms, Zach Galifianakis and Justin Bartha. It premiered on June 5, 2009 in the United States and its sequel is The Hangover: Part II (2011) and The Hangover: Part III (2013).