# data[].attributes.body
Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

Yes according to the articles I have read I am also convinced that the Philippine Ayta people have the most Denisovan DNA and in fact they are known to have more Denisovan DNA than the Papuan Highlanders. Researchers also found that from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers have discovered that the Ayta Magbukon in the Philippines have the highest level of Denisovan ancestry in the world.

Source:
https://www.sciencedaily.com/releases/2021/08/210812123052.htm

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Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers reporting in the journal Current Biology on August 12 have discovered that the Philippine Negrito ethnic group known as the Ayta Magbukon have the highest level of Denisovan ancestry in the world. In fact, they carry considerably more Denisovan DNA than the Papuan Highlanders, who were previously known as the present-day population with the highest level of Denisovan ancestry.

"We made this observation despite the fact that Philippine Negritos were recently admixed with East Asian-related groups -- who carry little Denisovan ancestry, and which consequently diluted their levels of Denisovan ancestry," said Maximilian Larena (@maxlarena) of Uppsala University. "If we account for and masked away the East Asian-related ancestry in Philippine Negritos, their Denisovan ancestry can be up to 46 percent greater than that of Australians and Papuans."

In the new study, Larena and colleagues, including Mattias Jakobsson, aimed to establish the demographic history of the Philippines. Through a partnership between Uppsala University of Sweden and the National Commission for Culture and the Arts of the Philippines (NCCA), aided by collaboration with indigenous cultural communities, local universities, local government units, non-governmental organizations, and/or regional offices of the National Commission for Indigenous Peoples, they analyzed about 2.3 million genotypes from 118 ethnic groups of the Philippines including diverse self-identified Negrito populations. The sample also included high-coverage genomes of AustraloPapuans and Ayta Magbukon Negritos.

The study shows that Ayta Magbukon possess the highest level of Denisovan ancestry in the world, consistent with an independent admixture event into Negritos from Denisovans. Together with the recent discovery of a small-bodied hominin, called Homo luzonensis, the data suggest that there were multiple archaic species that inhabited the Philippines prior to the arrival of modern humans, and that these archaic groups may have been genetically related.

Altogether, the researchers say that the findings unveil a complex intertwined history of modern and archaic humans in the Asia-Pacific region, where distinct Islander Denisovan populations differentially admixed with incoming Australasians across multiple locations and at various points in time.

"This admixture led to variable levels of Denisovan ancestry in the genomes of Philippine Negritos and Papuans," Jakobsson said. "In Island Southeast Asia, Philippine Negritos later admixed with East Asian migrants who possess little Denisovan ancestry, which subsequently diluted their archaic ancestry. Some groups, though, such as the Ayta Magbukon, minimally admixed with the more recent incoming migrants. For this reason, the Ayta Magbukon retained most of their inherited archaic tracts and were left with the highest level of Denisovan ancestry in the world."

"By sequencing more genomes in the future, we will have better resolution in addressing multiple questions, including how the inherited archaic tracts influenced our biology and how it contributed to our adaptation as a species," Larena said.

This work was supported by the Swedish Research Council and the Knut and Alice Wallenberg Foundation.
Story Source:
Materials provided by Cell Press. Note: Content may be edited for style and length.

Journal Reference:

Maximilian Larena, James McKenna, Federico Sanchez-Quinto, Carolina Bernhardsson, Carlo Ebeo, Rebecca Reyes, Ophelia Casel, Jin-Yuan Huang, Kim Pullupul Hagada, Dennis Guilay, Jennelyn Reyes, Fatima Pir Allian, Virgilio Mori, Lahaina Sue Azarcon, Alma Manera, Celito Terando, Lucio Jamero, Gauden Sireg, Renefe Manginsay-Tremedal, Maria Shiela Labos, Richard Dian Vilar, Acram Latiph, Rodelio Linsahay Saway, Erwin Marte, Pablito Magbanua, Amor Morales, Ismael Java, Rudy Reveche, Becky Barrios, Erlinda Burton, Jesus Christopher Salon, Ma. Junaliah Tuazon Kels, Adrian Albano, Rose Beatrix Cruz-Angeles, Edison Molanida, Lena Granehäll, Mário Vicente, Hanna Edlund, Jun-Hun Loo, Jean Trejaut, Simon Y.W. Ho, Lawrence Reid, Kurt Lambeck, Helena Malmström, Carina Schlebusch, Phillip Endicott, Mattias Jakobsson. Philippine Ayta possess the highest level of Denisovan ancestry in the world. Current Biology, 2021; DOI: 10.1016/j.cub.2021.07.022

Cite This Page:

# data[].attributes.attachment_link.keywords[]
multiple sclerosis research; human biology; genes; health policy; cultures; early humans; human evolution; anthropology

# data[].attributes.attachment_link.title
Philippine Ayta people have the most Denisovan DNA, study finds

# data[].attributes.attachment_link.description
Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers have discovered that the Ayta Magbukon in the Philippines have the highest level of Denisovan ancestry in the world.

# data[].attributes.headline
Do you think the Philippine Ayta people have the most Denisovan DNA? 

# data[].attributes.subject
Do you think the Philippine Ayta people have the most Denisovan DNA? 

# data[].attributes.body
RAMIRO,Ryan Joseph S

Yes, base on the studies I researched and was given to us, the Ayta people have the most Denisovan DNA. It is said that Indigenous people known as the Ayta Magbukon is carrying 5% of Denisovan DNA. (Brower,2021) They also believe that this tribe are carrying more Denisovan DNA that Papuan highlanders. This the result of interbreeding.

An Indigenous people in the Philippines have the most Denisovan DNA | Science Newshttps://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics

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Denisovans are an elusive bunch, known mainly from ancient DNA samples and traces of that DNA that the ancient hominids shared when they interbred with Homo sapiens. They left their biggest genetic imprint on people who now live in Southeast Asian islands, nearby Papua New Guinea and Australia. Genetic evidence now shows that a Philippine Negrito ethnic group has inherited the most Denisovan ancestry of all. Indigenous people known as the Ayta Magbukon get around 5 percent of their DNA from Denisovans, a new study finds.

This finding fits an evolutionary scenario in which two or more Stone Age Denisovan populations independently reached various Southeast Asian islands, including the Philippines and a landmass that consisted of what's now Papua New Guinea, Australia and Tasmania. Exact arrival dates are unknown, but nearly 200,000-year-old stone tools found on the Indonesian island of Sulawesi may have been made by Denisovans ( SN: 1/13/16). H. sapiens groups that started arriving around 50,000 years ago or more then interbred with resident Denisovans.

Evolutionary geneticists Maximilian Larena and Mattias Jakobsson, both at Uppsala University in Sweden, and their team describe the new evidence August 12 in Current Biology.

Even as the complexities of ancient interbreeding in Southeast Asia become clearer, Denisovans remain a mysterious crowd. "It's unclear how the different Denisovan groups on the mainland and on Southeast Asian islands were related [to each other] and how genetically diverse they were," Jakobsson says.

Papua New Guinea highlanders - estimated to carry close to 4 percent Denisovan DNA in the new study - were previously thought to be the modern record holders for Denisovan ancestry. But the Ayta Magbukon display roughly 30 percent to 40 percent more Denisovan ancestry than Papua New Guinea highlanders and Indigenous Australians, Jakobsson says. That calculation accounts for recent mating of East Asians with Philippine Negrito groups, including the Ayta Magbukon, that diluted Denisovan inheritance to varying degrees.

Genetic analyses suggest that Ayta Magbukon people retain slightly more Denisovan ancestry than other Philippine Negrito groups due to having mated less often with East Asian migrants to the island around 2,281 years ago, the scientists say. Their genetic analyses compared ancient DNA from Denisovans and Neandertals with that of 1,107 individuals from 118 ethnic groups in the Philippines, including 25 Negrito populations. Comparisons were then made to previously collected DNA from present-day Papua New Guinea highlanders and Indigenous Australians.

The new report underscores that "still today there are populations that have not been fully genetically described and that Denisovans were geographically widespread," says paleogeneticist Cosimo Posth of the University of Tübingen in Germany, who was not part of the new research.

But it's too early to say whether Stone Age Homo fossils found on Southeast Asian islands come from Denisovans, populations that interbred with Denisovans or other Homo lineages, Posth says. Only DNA extracted from those fossils can resolve that issue, he adds. Unfortunately, ancient DNA preserves poorly in fossils from tropical climates.

Only a handful of confirmed Denisovan fossils exist. Those consist of a few fragmentary specimens from a Siberian cave where Denisovans lived from around 300,000 to 50,000 years ago ( SN: 1/30/19), and a roughly 160,000-year-old partial jaw found on the Tibetan Plateau ( SN: 5/1/19).

Fossils from the Philippines initially classed as H. luzonensis, dating to 50,000 years ago or more ( SN: 4/10/19), might actually represent Denisovans. But a lack of consensus on what Denisovans looked like leaves the evolutionary identity of those fossils uncertain.

Larena and Jakobsson's findings "further increase my suspicions that Denisovan fossils are hiding in plain sight" among previously excavated discoveries on Southeast Asian islands, says population geneticist João Teixeira of the University of Adelaide in Australia, who did not participate in the new study.

Denisovans may have genetically encompassed H. luzonensis and two other fossil hominids found on different Southeast Asian islands, H. floresiensis on Flores and H. erectus on Java, Teixeira suspects. H. floresiensis, or hobbits, survived from at least 100,000 years ago to around 60,000 years ago ( SN: 6/8/16). H. erectus arrived on Java about 1.6 million years ago and died out between 117,000 and 108,000 years ago ( SN: 12/18/19).

Geographic ancestry patterns on Southeastern Asian islands and in Australia suggest that this region was settled by a genetically distinct Denisovan population from southern parts of mainland East Asia, Teixeira and his colleagues reported in the May Nature Ecology & Evolution.

Questions or comments on this article? E-mail us at feedback@sciencenews.org

Bruce Bower has written about the behavioral sciences for Science News since 1984. He writes about psychology, anthropology, archaeology and mental health issues.

# data[].attributes.attachment_link.title
An Indigenous people in the Philippines have the most Denisovan DNA

# data[].attributes.attachment_link.description
Denisovans are an elusive bunch, known mainly from ancient DNA samples and traces of that DNA that the ancient hominids shared when they interbred with Homo sapiens. They left their biggest genetic imprint on people who now live in Southeast Asian islands, nearby Papua New Guinea and Australia.

# data[].attributes.body
Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

Philippine Ayta people have the most Denisovan DNA, according to Cell Press,  Researchers have known for a long time that ancient hominins known as Denisovans interbred with modern humans, based on multiple lines of evidence. The Ayta Magbukon in the Philippines now have the greatest level of Denisovan heritage in the world, according to researchers. They really have a lot more Denisovan DNA than the Papuan Highlanders, who were previously thought to be the population with the most Denisovan ancestry.

Reference:
science daily, (2021).

Philippine Ayta people have the most Denisovan DNA, study finds. Retrieved from: https://www.sciencedaily.com/releases/2021/08/210812123052.htm

# data[].attributes.attachment_link.readable_text
Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers reporting in the journal Current Biology on August 12 have discovered that the Philippine Negrito ethnic group known as the Ayta Magbukon have the highest level of Denisovan ancestry in the world. In fact, they carry considerably more Denisovan DNA than the Papuan Highlanders, who were previously known as the present-day population with the highest level of Denisovan ancestry.

"We made this observation despite the fact that Philippine Negritos were recently admixed with East Asian-related groups -- who carry little Denisovan ancestry, and which consequently diluted their levels of Denisovan ancestry," said Maximilian Larena (@maxlarena) of Uppsala University. "If we account for and masked away the East Asian-related ancestry in Philippine Negritos, their Denisovan ancestry can be up to 46 percent greater than that of Australians and Papuans."

In the new study, Larena and colleagues, including Mattias Jakobsson, aimed to establish the demographic history of the Philippines. Through a partnership between Uppsala University of Sweden and the National Commission for Culture and the Arts of the Philippines (NCCA), aided by collaboration with indigenous cultural communities, local universities, local government units, non-governmental organizations, and/or regional offices of the National Commission for Indigenous Peoples, they analyzed about 2.3 million genotypes from 118 ethnic groups of the Philippines including diverse self-identified Negrito populations. The sample also included high-coverage genomes of AustraloPapuans and Ayta Magbukon Negritos.

The study shows that Ayta Magbukon possess the highest level of Denisovan ancestry in the world, consistent with an independent admixture event into Negritos from Denisovans. Together with the recent discovery of a small-bodied hominin, called Homo luzonensis, the data suggest that there were multiple archaic species that inhabited the Philippines prior to the arrival of modern humans, and that these archaic groups may have been genetically related.

Altogether, the researchers say that the findings unveil a complex intertwined history of modern and archaic humans in the Asia-Pacific region, where distinct Islander Denisovan populations differentially admixed with incoming Australasians across multiple locations and at various points in time.

"This admixture led to variable levels of Denisovan ancestry in the genomes of Philippine Negritos and Papuans," Jakobsson said. "In Island Southeast Asia, Philippine Negritos later admixed with East Asian migrants who possess little Denisovan ancestry, which subsequently diluted their archaic ancestry. Some groups, though, such as the Ayta Magbukon, minimally admixed with the more recent incoming migrants. For this reason, the Ayta Magbukon retained most of their inherited archaic tracts and were left with the highest level of Denisovan ancestry in the world."

"By sequencing more genomes in the future, we will have better resolution in addressing multiple questions, including how the inherited archaic tracts influenced our biology and how it contributed to our adaptation as a species," Larena said.

This work was supported by the Swedish Research Council and the Knut and Alice Wallenberg Foundation.
Story Source:
Materials provided by Cell Press. Note: Content may be edited for style and length.

Journal Reference:

Maximilian Larena, James McKenna, Federico Sanchez-Quinto, Carolina Bernhardsson, Carlo Ebeo, Rebecca Reyes, Ophelia Casel, Jin-Yuan Huang, Kim Pullupul Hagada, Dennis Guilay, Jennelyn Reyes, Fatima Pir Allian, Virgilio Mori, Lahaina Sue Azarcon, Alma Manera, Celito Terando, Lucio Jamero, Gauden Sireg, Renefe Manginsay-Tremedal, Maria Shiela Labos, Richard Dian Vilar, Acram Latiph, Rodelio Linsahay Saway, Erwin Marte, Pablito Magbanua, Amor Morales, Ismael Java, Rudy Reveche, Becky Barrios, Erlinda Burton, Jesus Christopher Salon, Ma. Junaliah Tuazon Kels, Adrian Albano, Rose Beatrix Cruz-Angeles, Edison Molanida, Lena Granehäll, Mário Vicente, Hanna Edlund, Jun-Hun Loo, Jean Trejaut, Simon Y.W. Ho, Lawrence Reid, Kurt Lambeck, Helena Malmström, Carina Schlebusch, Phillip Endicott, Mattias Jakobsson. Philippine Ayta possess the highest level of Denisovan ancestry in the world. Current Biology, 2021; DOI: 10.1016/j.cub.2021.07.022

Cite This Page:

# data[].attributes.attachment_link.keywords[]
multiple sclerosis research; human biology; genes; health policy; cultures; early humans; human evolution; anthropology

# data[].attributes.attachment_link.title
Philippine Ayta people have the most Denisovan DNA, study finds

# data[].attributes.attachment_link.description
Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers have discovered that the Ayta Magbukon in the Philippines have the highest level of Denisovan ancestry in the world.

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

Yes,  in my understanding, the studies conducted have shown that the Negritos that belong in the Ayta Magbukon had contact with the Denisovans that were already in the land, and because of this, there was crossbreeding between the two ethnicities. Through the years, the breeding between the two ethnicities was bound to their offsprings and because it was a closed group, the Denisovan ancestry was never altered and because of this, the Ayta Magbukon is now believed to have the greatest percentage of the Denisovan Lineage.

Source:
https://www.sciencedaily.com/releases/2021/08/210812123052.htm
https://www.uu.se/en/news/article/?id=17306&typ=artikel

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13 August 2021

The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relatives, the Denisovans, a new study led by Uppsala University shows. Their Denisovan share far exceeds that of ethnic groups in Papua New Guinea, who previously held the record. The study is published in the scientific journal Current Biology.

The Denisovans became known to science in 2010 with the sequencing of DNA from finger bones and teeth found in the Denisova Cave in Siberia. Despite good genetic information, who these people were remains a mystery, since only small bone fragments and teeth from them have been found. Scientists therefore use DNA technology in their quest to find out where the Denisovans lived, what they looked like and what happened to them. Today, thanks to these analyses, we know that they interbred both with our ancestors and with Neanderthals and, accordingly, that Denisovan genes, just like Neanderthal ones, are found in present-day humans. Among the inhabitants of parts of Oceania, in particular, the Denisovan genetic inheritance makes up a higher proportion of the genome than the genetic traces left by the Neanderthals do in modern humans.

The first inhabitants

The new study is part of a project aimed at finding out how the Philippines became populated. Previous interim results from the study have shown that Negritos, the ethnic group to which the Ayta Magbukon belong, were the first modern hominins to settle on the islands. The new findings indicate that the Negritos came into contact with the Denisovans already living there, and that there was interbreeding between the two groups. As a result, the Ayta Magbukon have a high level of Denisovan ancestry in their genome.

"Although, much later, Negritos admixed with the East Asian group that had a small proportion of Denisova DNA, we found that the Negritos had a proportion markedly higher than those of other ethnic groups. Compared with Australians and Papuans, the Negritos' Denisovan ancestry was up to 46 per cent higher," says Maximilian Larena of Uppsala University, the study's first author.

The researchers collaborated with cultural institutions in the Philippines, several local universities and indigenous peoples' organisations in the country. They analysed some 2.3 million genotypes from 118 ethnic groups in the Philippines, including various groups that self-identify as Negritos. Comprehensive genomes from AustraloPapuan and Ayta Magbukon Negritos were also included.

Combined with the discovery in 2019 of a small human relative called Homo luzonensis, the new results indicate that several archaic ethnic groups inhabited the Philippines before the arrival of Homo sapiens, and that the various groups may have been genetically related.

A clue to a mystery

The study also provides another clue to the mystery of the Denisovans, how they interacted with the modern humans and what happened to them subsequently.

In the scientists' view, the combined findings reveal a complex, intertwined history of present-day and archaic hominins in Oceania, where distinct island populations of Denisovans interbred with modern humans in several different places and at various times.

"This admixture resulted in varied levels of Denisovan genes in the genomes of Filipino Negritos and other groups. On Southeast Asian islands, Negritos later admixed with people who arrived from East Asia and had some Denisovan genes, which caused dilution in the share of Denisovan DNA. But some groups, such as Ayta Magbukon, interbred only a little with the people who later migrated to the islands. That's the reason why the Ayta Magbukon retained most of their Denisovan genes and therefore have the highest levels of those genes in the world," Mattias Jakobsson says.

"When we sequence more genomes in the future, we'll get a better insight into several different issues, including how the archaic inheritance has affected our biology and how it's contributed to our adaptation as a species," Maximilian Larena says.

# data[].attributes.attachment_link.title
Philippine ethnic group has most Denisovan DNA

# data[].attributes.attachment_link.description
The Philippine ethnic group Ayta Magbukon has the highest proportion of genes from our extinct relatives, the Denisovans, a new study led by Uppsala University shows. Their Denisovan share far exceeds that of ethnic groups in Papua New Guinea, who previously held the record. The study is published in the scientific journal Current Biology.

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Do you think the Philippine Ayta people have the most Denisovan DNA?

Yes. For this reason, studies show that the Philippine Ayta people have the most Denisovan DNA. To support this claim, a study in Sweden reported they carry more Denisovan DNA than the Papuan Highlanders, who were previously the highest level of Denisovan ancestry (CellPress, 2021). In addition to this, the studies also mentioned the Philippine Negritos. According to Maximilian Larena, they discovered that the Philippine Negritos carry a little Denisovan ancestry having a 46 percent greater than Australians and Papuans.

Source:
Cell Press. "Philippine Ayta people have the most Denisovan DNA, study finds." ScienceDaily. ScienceDaily, 12 August 2021.

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yes i believe there is. because the study shows that Ayta Magbukon possess the highest level of Denisovan ancestry in the world that is consistent with an independent admixture event into Negritos from Denisovans. Together with the recent discovery of a small-bodied hominin which it is called Homo luzonensis, the data suggest that there were multiple archaic species that inhabited the Philippines prior to the arrival of modern humans, and that these archaic groups may have been genetically related.

Sources:
Philippine Ayta people have the most Denisovan DNA, study finds. (2021, August 12). ScienceDaily. https://www.sciencedaily.com/releases/2021/08/210812123052.htm

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

# data[].attributes.body
Yes, I believe that Philippine Ayta people have the most Denisovan DNA, According to a study suggest that Ayta Magbukon people retain slightly more Denisovan ancestry than other Philippine Negrito groups due to having mated less often with East Asian migrants to the island around 2,281 years ago. The new study is part of a project aimed at finding out how the Philippines became populated. Previous interim results from the study have shown that Negritos, the ethnic group to which the Ayta Magbukon belong, were the first modern hominins to settle on the islands. The new findings indicate that the Negritos came into contact with the Denisovans already living there, and that there was interbreeding between the two groups. As a result, the Ayta Magbukon have a high level of Denisovan ancestry in their genome.

References:
Bower, B. (2021, August 23). An indigenous people in the Philippines have the most Denisovan DNA. Science News. https://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics.

Malmberg, Å. (n.d.). Philippine ethnic group has most Denisovan DNA. Philippine ethnic group has most Denisovan DNA - Uppsala University, Sweden. https://www.uu.se/en/news/article/?id=17306&typ=artikel.

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Yes, Filipino Ayta have the most Denisovan DNA according to the researchers in Sweden, Ayta Magbukon people have 5 per cent Denisovan ancestry, the experts say, which is around 30 to 40 per cent greater than that of Papuans and Australians.

Chadwick, J. (2021, August 12). Indigenous people in the Philippines have the highest level of DNA from our ancient ancestors the Denisovans

https://www.dailymail.co.uk/sciencetech/article-9886821/Filipino-ethnic-group-Denisovan-DNA-world-study-finds.html

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Yes. I do believe that Philippine Ayta people have the most Denisovan DNA. According to researches, Up to this point, researchers thought the advanced people with the most elevated extent of Denisovan lineage lived in Papua New Guinea and Australia. As indicated by another examination distributed yesterday (August 12) in Current Biology, be that as it may, an Indigenous gathering in the Philippines called the Ayta Magbukon to have 30 to 40 percent more Denisovan DNA than these other leaders, for a sum of almost 5% of their genomes. The researchers examined the genomes of 1,107 people having a place with 118 particular ethnic gatherings in the Philippines—including 25 gatherings self-recognizing as "Negritos," who are viewed as the most punctual present day human occupants of the Philippines, as indicated by The study creators. By contrasting these genomes with Denisovan and Neanderthal genomes, they found that while the level of Neanderthal family was genuinely uniform in their investigation populace (and tantamount to current people in different pieces of the world), the level of Denisovan parentage was exceptionally factor, and generously higher among Negritos than in different gatherings.

The study shows that Ayta Magbukon have the most elevated level of line in the world, reliable with a free admixture occasion into Negritos from Denisovans. Along with the new disclosure of a little bodied hominin, called Homo luzonensis, the information propose that there were different bygone species that occupied the Philippines before the appearance of current people, and that these antiquated gatherings might have been hereditarily related.

SOURCES:

https://www.the-scientist.com/news-opinion/indigenous-filipino-group-has-highest-known-denisovan-ancestry-69089

https://www.sciencedaily.com/releases/2021/08/210812123052.htm

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Until recently, scientists thought the modern humans with the highest proportion of Denisovan ancestry lived in Papua New Guinea and Australia. According to a new study published yesterday (August 12) in Current Biology, however, an Indigenous group in the Philippines called the Ayta Magbukon have 30 to 40 percent more Denisovan DNA than these other frontrunners, for a total of nearly 5 percent of their genomes.

Denisovans were a group of archaic humans first identified from a single pinkie bone in a Siberian cave. They coexisted with modern humans and other archaic human species, such as Neanderthals, for hundreds of thousands of years, until they went extinct an estimated 30,000 to 50,000 years ago. According to ,only Pacific Islanders and Southeast Asians have substantial Denisovan ancestry. By comparison, most people in other parts of mainland Asia have less than 0.05 percent Denisovan ancestry, and people of African and European descent don't have any.

"[The Ayta Magbukon] possess more Denisovan ancestry than anybody else on the planet today," Uppsala University biologist and study coauthor Mattias Jakobsson tells . "So that was a surprise to us."

According to Gizmodo, the researchers were originally interested in studying the human history of the Philippines as part of a massive collaborative effort with Indigenous communities, local governments, the National Commission for Culture and the Arts of the Philippines, and researchers at Uppsala University.

As a follow-up study to an earlier one studying human migrations to the Philippines, "we intended to look at the distant past by assessing the levels of archaic ancestry among the populations, especially that some populations in these regions were previously shown to have elevated levels of Denisovan ancestry and that Island Southeast Asia is known to be inhabited by various archaic species of Homo," population geneticist and study coauthor Maximilian Larena tells Gizmodo.

To do this, the researchers analyzed the genomes of 1,107 individuals belonging to 118 distinct ethnic groups in the Philippines-including 25 groups self-identifying as "Negritos," who are regarded as the earliest modern human inhabitants of the Philippines, according to the study's authors. By comparing these genomes to Denisovan and Neanderthal genomes, they found that while the degree of Neanderthal ancestry was fairly uniform in their study population (and comparable to modern humans in other parts of the world), the degree of Denisovan ancestry was highly variable, and substantially higher among Negritos than in other groups.

These findings "are consistent with a model of an independent interbreeding event between Negritos and Denisovans within the Philippines, suggesting that Denisovans may have been in the islands long before the presence of any modern human ethnic group," Larena tells Gizmodo.

University of Tübingen paleogeneticist Cosimo Posth, who was not involved in the study, tells Science Newsthe new report suggests that "still today there are populations that have not been fully genetically described and that Denisovans were geographically widespread."

Currently, the Denisovan fossil record is sparse, and according to Science News, Denisovan fossils can't be identified by morphology alone. They have to be genetically sequenced, which can be difficult when extracting fossils from tropical climates where the ancient DNA degrades more quickly.

The findings "further increase my suspicions that Denisovan fossils are hiding in plain sight," among previously excavated discoveries on Southeast Asian islands, University of Adelaide population geneticist João Teixeira tells Science News. Teixeira was not involved with the current study.

"When it comes to Southeast Asia and the Southeast Asian Islands, we have more questions than answers as we don't have a good archaeological record," University of Colorado Boulder population geneticist Fernando Villanea tells Inverse. Villanea, who was not involved with the study, adds, "Now we have these incredible genetic findings and we're having a hard time putting together a cohesive story."

"By sequencing more genomes in the future, we will have better resolution in addressing multiple questions, including how the inherited archaic tracts influenced our biology and how it contributed to our adaptation as a species," Larena says in the press release.

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Indigenous Filipino Group Has Highest Known Denisovan Ancestry

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Researchers found the relatively high proportion of DNA from a hominin cousin-nearly 5 percent-when they scanned more than 1,000 genomes from 118 distinct ethnic groups.

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According to a new study published last August 12, 2021, researchers in Sweden have observed that the Philippine Negrito Ethnic organization called the Ayta Magbukon, has the highest known Denisovan ancestry. With the genetic results suggesting that Denisovans also used to roam as far south as Indonesia, along with the fact that the Philippines was known to be first populated by ancient human beings, it is probable that indigenous tribes and modern humans came into contact with them. As a result of the interbreeding of these groups, this led to variable levels of Denisovan ancestry among Philippine Negritos. As to the concern regarding how they managed to possess 30%-40% greater Denisovan ancestry than their Australian and Papuan counterparts, I suppose it was because the Ayta people secluded themselves from the Spaniards in mountainous areas during colonization. For this reason, it led them to be able to preserve their cultural traditions and retain more of Denisovan DNA.

References:

Valdeavilla, R. (2018, May 15). The Aeta: The First Philippine People. Culture Trip. Retrieved from https://theculturetrip.com/asia/philippines/articles/the-aeta-the-first-philippine-people/

Dvorsky, G. (2021, August 12). Scientists Have Discovered a Hotspot of Denisovan Ancestor. Gizmodo. Retrieved from https://gizmodo.com/scientists-have-discovered-a-hotspot-of-denisovan-ances-1847473018

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

# data[].attributes.subject
Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

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Denisovans were a population of early humans who lived in Asia for a thousand of years before and even co-existed with modern humans in New Guinea. They were distantly related to the Neanderthals, another population of early humans in Europe and Western Asia. The Denisovans were first revealed by genes so they did not have proper classification and description until the pinky bone was found in the Denisova cave in Siberia. The Denisovan genes are also found in modern humans as based from the analysis of the scientists that the spread of Denisovans. From this, we can say that they have reached the Philippines which is part of South East Asia and interbred with the ancestors of modern Asian descent.

Negritos were the first inhabitants of our country and the analyses suggests that they have interbred with the Denisovans who settled in the islands of the Philippines. Mattias Jakobsson, Professor at the Department of Organismal Biology, said that the early group of Ayta did not interbred with the East Asian migrants as much as other Negritos which then preserved/retained a higher percentage of the Denisovan DNA.

Conde, Angela Nicole
BSA-2A

References:

Wei-Haas, M. (2021, May 3). Multiple lines of mysterious ancient humans interbred with us. Science. https://www.nationalgeographic.com/science/article/enigmatic-human-relative-outlived-neanderthals.

Malmberg, Å. (2021, August 13). Philippine ethnic group has most Denisovan DNA. Philippine ethnic group has most Denisovan DNA - Uppsala University, Sweden. https://www.uu.se/en/news/article/?id=17306&typ=artikel.

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

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Yes. Denisovans are an elusive bunch, known mainly from ancient DNA samples and traces of that DNA that the ancient hominids shared when they interbred with Homo sapiens. They left their biggest genetic imprint on people who now live in Southeast Asian islands, nearby Papua New Guinea and Australia. Genetic evidence now shows that a Philippine Negrito ethnic group has inherited the most Denisovan ancestry of all. Researchers from the Philippines and Sweden stumbled on the new findings as part of a wider study on human history in the Philippines that involved studying the genetic makeup of 118 different groups in the country. The study found that the Ayta Magbukon had around 5% Denisovan ancestry, more than Aboriginal Australians and Papuans, whom previous research found to have around 4%, said Mattias Jakobsson, a geneticist at Uppsala University in Sweden and an author of the study.  Denisovan ancestory is also present in many East Asian people although at a much lower level, other studies have found. The findings are further evidence that Denisovans once lived all throughout Asia and were likely living in the Philippines long before any Homo sapiens arrived. It also suggests that different Denisovan populations mixed and intermingled with Homo sapiens in multiple locations and various points in time.

De Leon, Genevi A.
BSA - 2A

Reference:

Hunt, K. (2021, August 16). New clue to human evolution's biggest mystery emerges in Philippines. CNN. https://edition.cnn.com/2021/08/16/world/denisovan-dna-philippines-scn/index.html

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Denisovans are an extinct group of early humans who lived in Asia. They were identified from a pinky finger bone and big molar teeth found in Denisova Cave in Siberia. They are the first hominin species to be revealed not by fossil classification but by genes alone— since none of the fossils found were enough to reconstruct their anatomical details. But through chemical modifications to the DNA they extracted from the bone, the computational biologists were able to map out a Denisovan’s skeletal features.

Yes, the Philippine group Ayta Magbukonon have the most Denisovan DNA. In a recent study, scientists found that the Philippine Ayta has the highest level of Denisovan ancestry and 46% higher proportion of Denisovan genes than those of Australians and Papuans ethnic groups who previously held the record. The researchers examined the genomes of 1,107 people from 118 different ethnic groups in the Philippines, which include "Negritos," who are believed to be the Philippines' first modern human inhabitants. They found that the Negrito’s Neanderthal ancestry are fairly uniform with the other groups and their Denisovan ancestry was substantially higher among other groups. Denisovans are regarded as a mystery in human evolution since their disappearance resembles a mass extinction and with the new discovery, it expands the diversity of our specie and also indicates that early modern humans coexisted in Asia and interbred with other hominin species.

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Do you think the Philippine Ayta People have the most Denisovan DNA?

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Do you think the Philippine Ayta People have the most Denisovan DNA?

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Dayno, Jovel Mari M. | BSA-2A

Yes. Denisovans are extinct species that have only been discovered about 10 years ago from a finger bone found in the Denisova cave where the name was derived from.  This Denisovan DNA found in some ethnic groups like the Aytas was due to the interbreeding that happened between Denisovans and modern humans a long time ago. From Siberia, they track down possible groups of people with archaic ancestry and relating to Denisovan DNA. This is where they come across to the southeast Asian part of the world and our country with a long history of inhabitants composing of both mixes of modern and archaic ancestry. In one of the studies, a thousand individuals from various ethnic groups in our country have been examined for their genetic composition. This analysis allowed the researchers to discover that the Ayta Magbukon Negritos has the highest percentage of Denisovan DNA than any other prior researches. There were also other Negrito groups who had been found with these Denisovan DNA but lesser. Having up to 46% Denisovan ancestry, even much greater than the Australians and Papuans, the Ayta Magbukon has the highest Denisovan Ancestry in the world. They retained this high inherited archaic ancestry as they have bred less with others outside their tribe.

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Do you think the Philippine Ayta people have the most Denisovan DNA?

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Do you think the Philippine Ayta people have the most Denisovan DNA?

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When ancient hominids interbred with Homo Sapiens, it would result in Denisovan DNA. Denisovans are believed to have inhabited the Siberian Cave because researchers found their finger bones and teeth. Moreover, their DNA left many questions unanswered. The researchers believed that Denisovans migrated to Southeast Asian islands such as Papua New Guinea and Australia as they found fossils and witnessed the genetic imprint of the Denisovan DNA to the indigenous people of the said country/ island. In the further study of the researchers, they have found that the Ayta Magbukon of the Philippines has a higher percentage of Denisovan DNA in their genetics compared to Indigenous people of Papua New Guinea and of Australia. Growing up in a place where there are Aytas and seeing pictures of Denisovans during my research, I agree that Ayta Magbukon has the Denisovans DNA. It is not impossible for Ayta to preserve or still have the DNA even though the Denisovans are long gone because they have been isolated in the mountains. When Spaniards and Americans colonized our country, the Aytas were isolated and remained in the mountains. Therefore, they can preserve the Denisovan DNA and never interbred with the colonizers.

References:

Bower, B. (2021, August 23). An indigenous people in the Philippines have the most Denisovan DNA. Retrieved September 06, 2021, from https://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics

Malmberg, Å. (n.d.). Philippine ethnic group has most Denisovan DNA. Retrieved September 06, 2021, from https://www.uu.se/en/news/article/?id=17306&typ=artikel

Abejero, Maria Rosalyn Joyce S.
BSA-2A

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Do you think the Philippine Ayta People have the most Denisovan DNA? 

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Do you think the Philippine Ayta People have the most Denisovan DNA? 

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Herrera, Simon Anthony V.
BSA-2A

Yes. To prove that the Aytas have the most Denisovan DNA, we must first try to piece out if such possibility is highly probable to occur. The Denisovans are a subspecies of humans that are closely similar to a Neanderthal. Before Homo sapiens dominated much of the human population, this particular subspecies of human intermingled with them. They were scattered through parts of Europe and western Asia. The proof of this can be found by how much traces of Denisovan DNAs have been found near parts of Papua New Guinea and Asia. Drawing from our first point, we can posit that it is possible that Denisovans have reached the parts of now modern day Philippines and intermingled with our early ancestors. They produced offspring that contained Denisovan DNAs but at the same time was repressed due to the Denisovan subspecies not being suitable towards the current conditions of the world.

Given that, we can conclude that it is possible for the Aytas to carry a Denisovan DNA, but why is it that they had the most? The previous record holder of the highest Denisovan DNA was a group of people from the Papua New Guinea. The remoteness that the jungles of New Guinea provides enabled the Denisovan DNA to remain at 4 percent. The Aytas, however, live in a much more secluded manner. Ever since the dawn of Spain, and perhaps even years before that (as the play of genetics in human evolution takes centuries), the Aytas lived in seclusion. They barred themselves from the lowland folks and the lowland folks did so vice versa. The remote mountains prevented a large volume of outsiders but also rendered the Aytas cut off from the rest of the Philippines. This is the reason why it should come as no shock that the Ayta people contained 5 percent of a Denisovan DNA. The circumstances around their lifestyle and how they built their culture allowed for the Denisovan DNA to remain strong in them.

References:
Wikipedia contributors. (2021, September 6). Denisovan. In Wikipedia, The Free Encyclopedia. Retrieved 13:46, September 6, 2021, from https://en.wikipedia.org/w/index.php?title=Denisovan&oldid=1042667075
Pääbo S. The diverse origins of the human gene pool. Nat Rev Genet. 2015 Jun;16(6):313-4. doi: 10.1038/nrg3954. PubMed: 25982166.
Bower, B. (2021, August 12). An Indigenous people in the Philippines have the most Denisovan DNA. Science News. https://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics?fbclid=IwAR3R2rOKuD5LvnnsnoolLkfOLtIUmeXnZUZk6IxvA1BtAryL-qzeeGAEjNY.
Cell Press. (2021, August 12). Philippine Ayta people have the most Denisovan DNA, study finds. ScienceDaily. Retrieved September 6, 2021 from www.sciencedaily.com/releases/2021/08/210812123052.htm

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Do you think the Philippine Ayta people have the most Denisovan DNA?

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Do you think the Philippine Ayta people have the most Denisovan DNA?

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Researchers have known for a long time that ancient hominins known as Denisovans interbred with modern humans, based on multiple lines of evidence. Researchers have revealed that the Philippine Negrito ethnic group known as the Ayta Magbukon has the greatest level of Denisovan ancestry in the world, according to a study published in the journal Current Biology on August 12. They really have a lot more Denisovan DNA than the Papuan Highlanders, who were previously thought to be the population with the most Denisovan ancestry.

Larena and colleagues, including Mattias Jakobsson, set out to demonstrate the Philippines' demographic history in their new study. They analyzed about 2.3 million genotypes from 11 indigenous peoples through a collaboration between Uppsala University in Sweden and the National Commission for Culture and the Arts of the Philippines (NCCA), aided by collaboration with indigenous cultural communities, local universities, local government units, non-governmental organizations, and/or regional offices of the National Commission for Indigenous Peoples.

According to the findings, Ayta Magbukon have the highest level of Denisovan ancestry in the globe, implying an independent mixing event between Negritos and Denisovans. The findings, together with the recent discovery of a small-bodied hominid known as Homo luzonensis, show that the Philippines was home to many archaic species prior to the arrival of modern humans, and that these archaic populations may have been genetically connected.

Shadelle Mickaela Alegria

Source: https://www.sciencedaily.com/releases/2021/08/210812123052.htm

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Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers reporting in the journal Current Biology on August 12 have discovered that the Philippine Negrito ethnic group known as the Ayta Magbukon have the highest level of Denisovan ancestry in the world. In fact, they carry considerably more Denisovan DNA than the Papuan Highlanders, who were previously known as the present-day population with the highest level of Denisovan ancestry.

"We made this observation despite the fact that Philippine Negritos were recently admixed with East Asian-related groups -- who carry little Denisovan ancestry, and which consequently diluted their levels of Denisovan ancestry," said Maximilian Larena (@maxlarena) of Uppsala University. "If we account for and masked away the East Asian-related ancestry in Philippine Negritos, their Denisovan ancestry can be up to 46 percent greater than that of Australians and Papuans."

In the new study, Larena and colleagues, including Mattias Jakobsson, aimed to establish the demographic history of the Philippines. Through a partnership between Uppsala University of Sweden and the National Commission for Culture and the Arts of the Philippines (NCCA), aided by collaboration with indigenous cultural communities, local universities, local government units, non-governmental organizations, and/or regional offices of the National Commission for Indigenous Peoples, they analyzed about 2.3 million genotypes from 118 ethnic groups of the Philippines including diverse self-identified Negrito populations. The sample also included high-coverage genomes of AustraloPapuans and Ayta Magbukon Negritos.

The study shows that Ayta Magbukon possess the highest level of Denisovan ancestry in the world, consistent with an independent admixture event into Negritos from Denisovans. Together with the recent discovery of a small-bodied hominin, called Homo luzonensis, the data suggest that there were multiple archaic species that inhabited the Philippines prior to the arrival of modern humans, and that these archaic groups may have been genetically related.

Altogether, the researchers say that the findings unveil a complex intertwined history of modern and archaic humans in the Asia-Pacific region, where distinct Islander Denisovan populations differentially admixed with incoming Australasians across multiple locations and at various points in time.

"This admixture led to variable levels of Denisovan ancestry in the genomes of Philippine Negritos and Papuans," Jakobsson said. "In Island Southeast Asia, Philippine Negritos later admixed with East Asian migrants who possess little Denisovan ancestry, which subsequently diluted their archaic ancestry. Some groups, though, such as the Ayta Magbukon, minimally admixed with the more recent incoming migrants. For this reason, the Ayta Magbukon retained most of their inherited archaic tracts and were left with the highest level of Denisovan ancestry in the world."

"By sequencing more genomes in the future, we will have better resolution in addressing multiple questions, including how the inherited archaic tracts influenced our biology and how it contributed to our adaptation as a species," Larena said.

This work was supported by the Swedish Research Council and the Knut and Alice Wallenberg Foundation.
Story Source:
Materials provided by Cell Press. Note: Content may be edited for style and length.

Journal Reference:

Maximilian Larena, James McKenna, Federico Sanchez-Quinto, Carolina Bernhardsson, Carlo Ebeo, Rebecca Reyes, Ophelia Casel, Jin-Yuan Huang, Kim Pullupul Hagada, Dennis Guilay, Jennelyn Reyes, Fatima Pir Allian, Virgilio Mori, Lahaina Sue Azarcon, Alma Manera, Celito Terando, Lucio Jamero, Gauden Sireg, Renefe Manginsay-Tremedal, Maria Shiela Labos, Richard Dian Vilar, Acram Latiph, Rodelio Linsahay Saway, Erwin Marte, Pablito Magbanua, Amor Morales, Ismael Java, Rudy Reveche, Becky Barrios, Erlinda Burton, Jesus Christopher Salon, Ma. Junaliah Tuazon Kels, Adrian Albano, Rose Beatrix Cruz-Angeles, Edison Molanida, Lena Granehäll, Mário Vicente, Hanna Edlund, Jun-Hun Loo, Jean Trejaut, Simon Y.W. Ho, Lawrence Reid, Kurt Lambeck, Helena Malmström, Carina Schlebusch, Phillip Endicott, Mattias Jakobsson. Philippine Ayta possess the highest level of Denisovan ancestry in the world. Current Biology, 2021; DOI: 10.1016/j.cub.2021.07.022

Cite This Page:

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multiple sclerosis research; human biology; genes; health policy; cultures; early humans; human evolution; anthropology

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Philippine Ayta people have the most Denisovan DNA, study finds

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Researchers have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers have discovered that the Ayta Magbukon in the Philippines have the highest level of Denisovan ancestry in the world.

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Denisovan is a population of early humans. According to studies the Denisovan population is closely related to another race which is the Neanderthal, they shared a common ancestor which is the Homo Sapiens. These two groups were believed to reside around Eurasia.  On the other hand, the Denisovan fossils were found at the Denisovan cave in Siberia (A region in Russia, and historically Siberia includes all Russian territories in North Asia), the potential traces of Denisovans were not just bound at Siberia, there are also fossils from China, although these fossils were proven that it is not from Denisovans. With further studies, it is found that there were two distinct groups of Denisovans, those genes that were found in Mainland Asia and genes that were found in Melanesians.

Tracing back the History of the Philippine Ayta People, they had an Australo-Melanesian race or also called as Australoid race. These races have dark skin, wavy, straight, kinky, or silky hair, that is colored light brown. Unlike other Australo-Melanesians in other countries, the Philippine Ayta people retained their culture and preserve the genes that they acquire from their ancestors. The Ayta tribe is one of the tribes that resisted being penetrated by the colonizers, so we can assume that the Denisovan DNA is still embedded in their blood.   With the studies that were conducted in the Aeta tribe, yes, they have the most Denisovan DNA, more than the other tribes that are similar to theirs. According to a study about Philippine Aeta people, the Ayta people have nearly five percent of the Denisovan DNA which was not found even in the place where the researchers believed that Denisovans reside.

Source:

Dvorsky, G. (2021) Denisovan Ancestors

Retrieved From:
Scientists Have Discovered a Hotspot of Denisovan Ancestors (gizmodo.com)

Melchor, A. (2021) Indigenous Filipino group has the highest Denisovan Ancestry

Retrieved from:

Indigenous Filipino Group Has Highest Known Denisovan Ancestry | The Scientist Magazine® (the-scientist.com)

Unknown (2021) Denisovan History
Retrieved From:
https://www.newscientist.com/definition/denisovans/

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Do you think the Philippine Ayta People have the most Denisovan DNA? (Acorda)

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Do you think the Philippine Ayta People have the most Denisovan DNA? (Acorda)

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To answer this particular question, One must first understand what and who were the Denisovan people.  The denisovan people are the last known humans to have walked the earth before we did. The discovery of their remains in Siberia rewrote Human history as we know it (Wei-Haas,2021). Yes, I do believe that the Ayta people have the most "Denisovan DNA" in the world. To prove, Melchor (2021) stated that the ones that were considered most denisovan were the natives from Papua New Guinea, but through scientific testing it has been determined that our very own Ayta people have the most Denisovan genome. Particuarly, the Ayta Magbukon whose located primarily in Bataan has 30-40 percent similarity with the Denisovans making these people some of the most pure born descendants or relatives of our distant archaic relatives (Llemit,2021). Now, these wouldn't have been possible if these people have intermixed with others. However, these people have been isolated from common filipinos for hundreds of years starting from the landing of the spanish all the way to present time thus preserving their denisovan relativity which is absolutely fascinating.

Sources:
Llemit, K. A. (2021, August 20). Philippines’ Ayta found to have world’s highest percentage of Denisovan ancestry. Philstar.Com. https://www.philstar.com/lifestyle/arts-and-culture/2021/08/20/2121429/philippines-ayta-found-have-worlds-highest-percentage-denisovan-ancestry

Melchor, A. (2021, August 13). Indigenous Filipino Group Has Highest Known Denisovan Ancestry. The Scientist Magazine®. https://www.the-scientist.com/news-opinion/indigenous-filipino-group-has-highest-known-denisovan-ancestry-69089

Wei-Haas, M. (2021, May 3). Multiple lines of mysterious ancient humans interbred with us. Science. https://www.nationalgeographic.com/science/article/enigmatic-human-relative-outlived-neanderthals

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According to researches, the Ayta The Ayta Magbukon is said to have Denisovan DNA 30-40% greater than other humans around the globe. It was when mysterious remains was found in a cave in Siberia, but Philippine Negritos are thought to be the earliest human population to have migrated to the Philippines. There was evidence that many of the Negrito populations had previously mixed with East Asian populations, who have much less genetic contribution from Denisovans in their genome.  The information was proven with the aid of population genetic data and computational analyses that confirmed the Ayta Magbukon has the highest of Denisovan DNA in the world. Some believed they had lesser interbreeding with foreigners as for their traditions. Which caused them to maintain most of their inherited traits and having the highest Denisovan blood in them.

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According to researches, the Ayta The Ayta Magbukon is said to have Denisovan DNA 30-40% greater than other humans around the globe. It was when mysterious remains was found in a cave in Siberia, but Philippine Negritos are thought to be the earliest human population to have migrated to the Philippines. There was evidence that many of the Negrito populations had previously mixed with East Asian populations, who have much less genetic contribution from Denisovans in their genome.  The information was proven with the aid of population genetic data and computational analyses that confirmed the Ayta Magbukon has the highest of Denisovan DNA in the world. Some believed they had lesser interbreeding with foreigners as for their traditions. Which caused them to maintain most of their inherited traits and having the highest Denisovan blood in them.

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References:

Llemit, K. A. (2021, August 20). Philippines’ Ayta found to have world’s highest percentage of Denisovan ancestry. Philstar.Com. https://www.philstar.com/lifestyle/arts-and-culture/2021/08/20/2121429/philippines-ayta-found-have-worlds-highest-percentage-denisovan-ancestry#:%7E:text=The%20Ayta%20Magbukon%2C%20mostly%20found,their%20Australian%20and%20Papuan%20counterparts.

Mackenzie, R. J. (2021, August 12). Ethnic Group in the Philippines Have Highest Level of Denisovan DNA in the World. Genomics Research from Technology Networks. https://www.technologynetworks.com/genomics/news/ethnic-group-in-the-philippines-have-highest-level-of-denisovan-dna-in-the-world-351974

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Genomics Research from Technology Networks

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A study analyzing the genomes of nearly 120 ethnic groups in the Philippines has identified that one population, the Ayta Magbukon, have the highest level of DNA derived from Denisovans, an extinct human subspecies, recorded to date.

Denisovans, unlike the better-studied Neanderthals, were only discovered by modern science around a decade ago, when mysterious remains found in a cave in Siberia turned out to be from the previously unidentified subspecies.

From Siberia to Southeast Asia

Since that finding, scientists have only found Denisovan DNA in one other location, the Baishiya Karst Cave site of the Tibetan Plateau. Computational analysis using the genome found in Siberia has enabled researchers to quantify the contribution of Denisovan DNA to the genomes of modern-day humans. Previous research had identified that Australasians have the highest level of Denisovan DNA relative to any other population.

But the Australasian population covers a vast area of Island Southeast Asia (ISEA), including the complex ethnic melting pot of the Philippines. Here, well over 100 distinct ethnic groups occupy 2,000 inhabited islands. In the new study, a team of Filipino and international researchers examined DNA from 1,107 individuals across 118 ethnic groups with 2.3 million different genetic point variations.

Who are the Philippine Negritos?
Philippine Negritos are thought to be the earliest human population to have migrated to the Philippines. At least 30 self-identified Negrito groups speak different Malayo-Polynesian languages. The researchers noted that the 25 groups who were contacted in this study were spread across hunting and gathering, subsistence and urbanized lifestyles, with many of their languages regarded as severely endangered.

The in-depth analysis highlighted that the Ayta Magbukon Negrito genome contains the highest proportion of Denisovan DNA. The Ayta Magbukon population, who the authors believe have not previously been investigated in any genomic study, occupy the Central Luzon province of Bataan. There was evidence that many of the Negrito populations had previously mixed with East Asian populations, who have much less genetic contribution from Denisovans in their genome. Using a genomic tool called masking, the researchers, including Uppsala University's Maximilian Larena, were able to pinpoint the significant differences in genomic contribution. "If we account for and masked away the East Asian-related ancestry in Philippine Negritos, their Denisovan ancestry can be up to 46% greater than that of Australians and Papuans," said Larena, in a press release.

The findings were surprising to the team. Previous studies suggested that a relatively simple, one-off mixing event had occurred between Australasians and Denisovans, but these new findings imply multiple mixing events have occurred across different locations and timepoints. "In [ISEA], Philippine Negritos later admixed with East Asian migrants who possess little Denisovan ancestry, which subsequently diluted their archaic ancestry. Some groups, though, such as the Ayta Magbukon, minimally admixed with the more recent incoming migrants. For this reason, the Ayta Magbukon retained most of their inherited archaic tracts and were left with the highest level of Denisovan ancestry in the world," the authors explain in the publication.

The new findings pair with the recent discovery of the remains of another previously unidentified extinct human species, Homo luzonensis, in Luzon, the Philippines' largest island. Together, the authors suggest that there is a rich tapestry of ancient human interaction waiting to be discovered in ISEA. Piecing that picture together could reveal secrets of the entire human race. "By sequencing more genomes in the future, we will have better resolution in addressing multiple questions, including how the inherited archaic tracts influenced our biology and how it contributed to our adaptation as a species," Larena concluded.

Reference:

Larena M, McKenna J, Sanchez-Quinto F, et al. Philippine Ayta possess the highest level of Denisovan ancestry in the world. Current Biology. 2021;31:1-12. doi: 10.1016/j.cub.2021.07.022

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Ethnic Group in the Philippines Have Highest Level of Denisovan DNA in the World

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A study analyzing the genomes of nearly 120 ethnic groups in the Philippines has identified that one population, the Ayta Magbukon, have the highest level of DNA derived from Denisovans, an extinct human subspecies, recorded to date.

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Denisovan DNA was the way to know who are the people that got the ancient hominids heredity. Research says that the people in the Southeast Asian islands got the genes, and the Philippines is included in these countries. With that, the study says that most population of Denisovans passed through the islands of Southeast Asia, especially the Philippine Negrito Ethnic group.
In addition, Ayta Magbukon from the Philippines, who are commonly known as the Indigenous people, arrived at the information that 5 percent of their DNA are Denisovans. To compare with Papua New Guinea highlanders and Indigenous Australians, Ayta Magbukon evinced to have 30% to 40% of Denisovan Ancestry than the two. However, there will still be further studies to end the confusion between the genetic difference of Denisovan groups on the mainland and the islands of Southeast Asia. To conclude, according to my research, the Philippine Ayta group has the most Denisovan DNA.

Reference:

Bower, B. (2021, August 21). An Indigenous people in the Philippines have the most Denisovan DNA. Retrieved 4 September 2021, from https://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics

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Yes, according to researchers, they have known from several lines of evidence that the ancient hominins known as the Denisovans interbred with modern humans in the distant past. Now researchers reporting in the journal Current Biology on August 12 have discovered that the Philippine Negrito ethnic group known as the Ayta Magbukon have the highest level of Denisovan ancestry in the world. In fact, they carry considerably more Denisovan DNA than the Papuan Highlanders, who were previously known as the present-day population with the highest level of Denisovan ancestry.

Reference:
ScienceDaily. (2021, August 12). Philippine Ayta people have the most Denisovan dna, study finds. ScienceDaily. https://www.sciencedaily.com/releases/2021/08/210812123052.htm.

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According to a study, Denisovan genes were abundant among ISEA (Island Southeast Asia) populations and going back in our human history, the Philippines Negritos was the first group of people who migrated in the Philippines that carry the most Denisovan DNA. As our original ancestors encountered and interacted with these immigrants, it is given that interbreeding was inevitable and often pervasive. Hence, I believe that Ayta people having the most Denisovan DNA is not far from being a fact.

Further, with the aid of population genetic data and computational analyses, a new paper investigating the ancient ancestry across several Philippine ethnic groups claims that Ayta Magbukon have the highest level of Denisovan ancestry in the world. This is owing to the Ayta magbukon people's lesser admixing with more recent incoming immigrants compared to those who migrated earlier (Genomeweb, 2021), causing them to maintain most of their inherited archaic tracts and leave them with the highest level of Denisovan ancestry.

References:

Luntz, S. (2021, August 15). Indigenous Group In The Philippines Has Most Denisovan DNA in the World. IFLScience. https://www.iflscience.com/editors-blog/indigenous-group-in-the-philippines-has-most-denisovan-dna-in-the-world/

Teixeira, J. C. (2021, March 22). Widespread Denisovan ancestry in Island. . . Nature Ecology & Evolution. https://www.nature.com/articles/s41559-021-01408-0?error=cookies_not_supported&code=35d38117-b0d2-43ec-845b-55b1ce9e7dbe

Genomeweb. (2021, August 12). Population Study Points to Pronounced Denisovan Ancestry in Philippine Population. https://www.genomeweb.com/sequencing/population-study-points-pronounced-denisovan-ancestry-philippine-population#.YTL0GZ0zZPY

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Yes, I think that Philippine Ayta people have the most Denisovan DNA. According to research, Ayta Magbukon is found to be the most modern Denisovan DNA in the world because most of the ancestors of the Ayta are Denisovan. Ayta Magbukon has a 5% percent Denisovan ancestry which is higher than other peninsulas. I believe that their traditions are well-connected to the Denisovan and stayed in that single place to preserve their bloodline. Since their bloodline doesn't mix with lowland people which means to say that their DNA around them would never be mixed with others instead it would still connect to the Denisovan DNA.  

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Yes, I think that Philippine Ayta people have the most Denisovan DNA. According to research, Ayta Magbukon is found to be the most modern Denisovan DNA in the world because most of the ancestors of the Ayta are Denisovan. Ayta Magbukon has a 5% percent Denisovan ancestry which is higher than other peninsulas. I believe that their traditions are well-connected to the Denisovan and stayed in that single place to preserve their bloodline. Since their bloodline doesn't mix with lowland people which means to say that their DNA around them would never be mixed with others instead it would still connect to the Denisovan DNA.  

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citation: Report, S. (2021, August 18). Philippines' Ayta group found to have 'highest level' of Denisovans DNA. Retrieved September 04, 2021, from https://filipinotimes.net/latest-news/2021/08/18/philippines-ayta-group-found-to-have-highest-level-of-denisovans-dna/

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer.

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer. (Camacho, Abegail)

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Do you think the Philippine Ayta people have the most Denisovan DNA? Explain your answer. (Camacho, Abegail)

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Yes, I believe that they do. I have noticed before that their culture and physical attributes are different from us and just recently, Maximilian Larena and Mattias Jakobsson, have conducted a study that proves that the Philippine Ayta does indeed have Denisovan DNA. According to their study, they have about 5% of this DNA. This is relatively high compared to other pre-existing groups that they were also gathering data from. It was discovered that the early hominids that bred with Homo sapiens left genetic imprints on Southeast Asian Islands, Papua New Guinea, and Australia. The data that they have gathered paved a way to connect the evolutionary scenarios that were gathered by previous evolutionary geneticists. The highlanders from Papua New Guinea was believed to hold the record of having the highest percentage of Denisovan DNA but due to the recent discovery, it is actually the Ayta Magbukan who was said to have about 30 to 40 percent ancestry more than tribes from Papua New Guinea — this is due to the fact that the Ayta has bred less, therefore, they were able to retain more of the Denisovan DNA than other highlanders or tribes who were believed to also carry this kind of gene.

Reference:

Bower, B. (2021, August 12). An Indigenous people in the Philippines have the most Denisovan DNA. Science News. https://www.sciencenews.org/article/indigenous-people-philippines-denisovan-dna-genetics?fbclid=IwAR3R2rOKuD5LvnnsnoolLkfOLtIUmeXnZUZk6IxvA1BtAryL-qzeeGAEjNY.