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Exposition
Charlie Gordon, a 32-year-old man with a low I.Q. and developmental disabilities, has been selected to undergo an experimental surgery to boost his intelligence. He should start maintaining a notebook to document his ideas and development, according to the physicians.

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Charlie spends his entire life trying to become intelligent.

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After Dr. Strauss conducts an experimental surgery on Charlie, his IQ soars to genius levels. Charlie then falls in love with Alice but is unable to marry her due of unresolved childhood guilt over his sexuality.

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By fleeing the researchers who are monitoring him, Charlie declares his independence.

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Charlie finds his mother and sister and is able to forgive them for how they abused him as a youngster; Charlie finds the error in Nemur's hypothesis that demonstrates he would soon lose his IQ; Charlie and Alice have a fleeting but meaningful relationship; Charlie goes back to being Charlie.

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Charlie choosing to reside at Warren State Home.