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Section of epididymis. Connective tissue (blue) is seen supporting the epithelium (purple)

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Section of epididymis. Connective tissue (blue) is seen supporting the epithelium (purple)

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Clinical significance of connective tissue

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Clinical significance of connective tissue

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It is estimated that 1 in 10 people have a connective tissue disorder. Diseases of connective tissue include:

Connective tissue neoplasms including sarcomas such as hemangiopericytoma and malignant peripheral nerve sheath tumor in nervous tissue.

Congenital diseases include Marfan syndrome and Ehlers-Danlos Syndrome.

Myxomatous degeneration – a pathological weakening of connective tissue.

Mixed connective tissue disease – a disease of the autoimmune system, also undifferentiated connective tissue disease.

Systemic lupus erythematosus (SLE) – a major autoimmune disease of connective tissue

Scurvy, caused by a deficiency of vitamin C which is necessary for the synthesis of collagen.

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Cells are spread through an extracellular fluid.

Ground substance - A clear, colorless, and viscous fluid containing glycosaminoglycans and proteoglycans to fix the body water and the collagen fibers in the intercellular spaces. Ground substance slows the spread of pathogens.

Fibers. Not all types of CT are fibrous. Examples of non-fibrous CT include adipose tissue and blood. Adipose tissue gives "mechanical cushioning" to the body, among other functions. Although there is no dense collagen network in adipose tissue, groups of adipose cells are kept together by collagen fibers and collagen sheets in order to keep fat tissue under compression in place (for example, the sole of the foot). The matrix of blood is plasma.

Both the ground substance and proteins (fibers) create the matrix for CT.

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Bone

Location: bones.

Function: bones supports and protects.

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Blood

Location: contained within blood vessels.

Function: transport of respiratory gases, nutrients, wastes, and other substances.

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3.The graph of Fibrous connective tissue

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3.The graph of Fibrous connective tissue

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Fibrous connective tissue

Location: tendons and ligaments.

Function: attach muscles to bones and connect bones at joints.

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Cartilage Tissue

Location: the nose ,ears and several of the body's joints.

Function: protects bones, supports the shape(such as ears and noses).

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1.(3).The graph of Reticular Connective Tissue

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1.(3).The graph of Reticular Connective Tissue

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Reticular Connective Tissue

Location: Around organs such as the liver, kidney, spleen, and lymph organs.

Function: To support and hold together organs and adipose tissue (fat).

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1.(2).The graph of Adipose Connective Tissue 

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1.(2).The graph of Adipose Connective Tissue 

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Adipose Connective Tissue (Fat)

Location: Around organs, subcutaneous layer (between skin and muscle)

Function: Store energy, provide protection, and insulate.

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1.(1).The graph of areolar connective tissue

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1.(1).The graph of areolar connective tissue

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Areolar Connective Tissue

Location: Around blood vessels, nerves, and organs.

Function: Provides strength, elasticity, support and immune system protection.

( three types of fibres collagen ,elastic and reticular )

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The types of connective tissues formed by combining the fibres and foundation(in vertebrates).

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The types of connective tissues formed by combining the fibres and foundation(in vertebrates).

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1.Loose connective tissue.
Loose connective tissue binds epithelia to underlying tissues and holds organs in place
（1）Areolar Connective Tissue

（2）Adipose Connective Tissue (Fat)

（3）Reticular Connective Tissue

2.Cartilage
Cartilage is a strong and flexible support material.

3.Fibrous connective tissue
Fibrous connective tissue is dense with collagenous fibers.

4.Blood
Blood  is composed of blood cells and cell fragments in blood plasma.

5.Bone
Bone is a mineralized connective tissue and forms the skeleton.

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Types of fibres of the connective Tissue:

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Types of fibres of the connective Tissue:

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Reticular Fibre tends to form a network or mas that supports most of soft tissues.

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Macrophages are large, specialized cells that recognize, engulf and destroy target cells. They are formed through differentiation of monocytes, one of the major groups of white blood cells of the immune system.
A fibroblast is a type of cell that is responsible for making the extracellular matrix and collagen.

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Connective Tissue:

It is the responsible for holding and providing the shape of the body.

Let`s think about a house. It is built up with bricks and cement. Furthermore, in order to make it more resistant the structure need to be reinforced with rods.

This analogy applies for the connective tissue because it is composed by cells(bricks), supported by abundant intercellular substance (cement) and it also contains tissue fibres(rods).