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Brief Comparison of Qualitative and Quantitative Research Methods

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A brief overview of the research process for an INTD 100 assignment (Whittier College).

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Title :  Role of bone marrow transplant in leukemia .

Aim :  To assess the role of bone marrow transplant in leukemia.

Objective:
1-To compare between different outcomes of different leukemia therapies and bone marrow transplantation.
2-To assess the effect of bone marrow transplantation in quality of life of the patient.

Research problem :  Many leukemia patient  are preferring chemotherapy ,radiotherapy or other kinds of treatments rather than bone marrow transplant ,although it has less adverse effects , and over years the percentage of successful transplantations has increased noticeably.

Rifga Kamil Ibrahim
1001748260

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Title : Ultra Violet radiation and development of non melanoma skin cancer NMSC

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Title : Ultra Violet radiation and development of non melanoma skin cancer NMSC

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Aim: To assess the risk of NMSC associated with ultra violet radiation.
Objective:
1. To estimate the possibility of NMSC due to stratospheric ozone depletion
2. To study the mechanism of DNA mutation caused by UV radiation
Research questions:
1. How the sun exposure can effect keratocytes mutation?
2. Is the intensity of the UV radiation correlate with degree of NMSC  occurrence?
Dear Ms. Nahib,
Correct the following
1. Title case
2. Refer the instruction provided my me in the bold letters and correct it.

Nahid Abdelwhab Taha
ID 1001747498

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Title: New Therapeutic Agent for Advanced Prostate Cancer

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Title: New Therapeutic Agent for Advanced Prostate Cancer

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Research problem:

Prostate cancer death are usually the result of Metastatic Castration Resistant Prostate Cancer (MCRPC)  and the median survival for men with MCRPC has been less than two years, while the German Society of Nuclear Medicine demonstrates that lutetium-177 labeled with prostate specific membrane antigen-617 (lu-177psma-617) is promising new therapeutic agent for Radioligand Therapy (RLT) of patients with MCRPC, future phase 2 and phase 3 studies are needed to clarify the survival benefits of this new therapy is not FDA-approved .

Research question:

How Radioligand Therapy (lu-177psma-617) increases and improves median survival for men with metastatic castration resistant prostate cancer?

Aim:

To prove that (lu-177psma-617) Radioligand Therapy is safe and more effective than other third-line systemic therapies for MCRPC patients

Objectives:

1-      To identify the effect and the expression of (lu-177 psma-617) Radioligand Therapy on MCRPC patients

2-      To improve this new therapy at earlier stages of disease with even higher response rate and low toxicity

3-      To evaluate the possible therapeutics of this new drug on different types of cancer such as breast cancer and kidney cancer

Name: Khadija Mallouk

Student number :1001748710

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Title: Control the risk of breast cancer induced by combine oral hormonal replacement therapy

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Title: Control the risk of breast cancer induced by combine oral hormonal replacement therapy

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Aim:
Reduce the side effect of combine oral hormonal replacement therapy (HRT) target on breast cancer.

Objective:

1. To identify the therapeutic efficacy and possible side effect of combine oral HRT.

2. To identify the mechanism of action that develops breast cancer for combine oral HRT.

3. To design such combine oral HRT that will be not responsible for breast cancer.

Research Question:

1. How the combine oral hormonal HRT responsible for breast cancer?

2. How to identify the therapeutic efficacy and possible side effect of combine oral HRT?

3. What possible ways reduce the risk factor of breast cancer for combine oral HRT?

Problem of the Statement:

The risk of developing breast cancer is increased for women using any type of HRT, but the risk is greatest for women using the combined type. The users of combined HRT have double the risk of breast cancer compared to non-users. Higher-dose combination HRT increases breast cancer risk more than lower-dose combination HRT. Investigation is needed to determine the appropriate reason of breast cancer caused by combine oral HRT and ensure to reduce the chance of breast cancer in regards to user’s quality life.

Tahani Islam
ID No.: 1001746194

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Title: Research on benefits of taking turmeric supplement in cancer patient

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Title: Research on benefits of taking turmeric supplement in cancer patient

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Aim:
To assess the improvement of quality of life in term of slowing down the progression of disease in cancer patient by taking turmeric supplement

Objective:
1. To assess if slowing down of progression of cancer at patient who are taking turmeric supplement.
2. To identity the mechanism of action if turmeric slow down the cancer progression.
3. To investigate the percentage of it slow down the progression of cancer by taking the tumeric supplement.
4. To determine the maximum and minimum dosage of turmeric to get a desired effect.

Research Problem:
In the previous studies, it shown that cancer can be prevented by taking turmeric. While there are cancer patients seeking for the supplement to improve their quality of life, in term of less side effects from the therapy and also slow down the progression of cancer. Benefits by taking turmeric to the diagnosed cancer patient is less researched and warrants investigation.

Yoo Keat Jiu

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Dear All,

Well done. I request all the students to write their name or roll number in the bottom of the post.

Note:

Work to do

Refer the below given website and post your research question in the padlet (reflect the title and aim in the questions within 10 days).

https://writingcenter.gmu.edu/guides/how-to-write-a-research-question

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The benefit of complementary medicine to cancer patients on chemotherapy 

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The benefit of complementary medicine to cancer patients on chemotherapy 

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Aim : To reduce the time frame of suffering for cancer patients by complementary medication and improve their survival rate.

Obj : 1. To analyse the no. Of patients on chemotherapy and complementary medicine at a time.
2. To understand the effectiveness and side effect of complementary medicine to a patient.
3. To review the patient`s take on complementary medicine.
Pretha

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Review and development of health warning signs for tobacco packages in lung cancer 

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Review and development of health warning signs for tobacco packages in lung cancer 

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Aim:
to review And evaluation of impact of the existing text and picture warnings, and develop a proposal for warning messages of tobacco in lung cancer
Objectives:
1. To review of scientific knowledge of lung cancer caused by tobacco
2. To evaluate health warning signs in tobacco packages towards tobacco consumers.
3. To develop possible warning messages of tobacco packages in lung cancer based on review.

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Title: Case control study: Comparison between the efficiency of targeted radiotherapy and chemotherapy in limiting side effects of breast cancer treatment 

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Title: Case control study: Comparison between the efficiency of targeted radiotherapy and chemotherapy in limiting side effects of breast cancer treatment 

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Aim:
To assess the efficiency of targeted radiotherapy in limiting side effects of breast cancer treatment when compared with chemotherapy.
Objective:
1. To identify the therapeutic efficacy of targeted radiotherapy and chemotherapy on breast cancer.
2. To determine the percentage of breast cancer patients experiencing from side effects after receiving targeted radiotherapy and chemotherapy.
3. To identify the types and number of side effects experienced by breast cancer patient after receiving targeted radiotherapy and chemotherapy.
4. To establish the quality of life in breast cancer patient after receiving targeted radiotherapy and chemotherapy.
Mooi Xin Yi 1001335246

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A randomized controlled trial comparing the efficacy and toxicity of cisplatin-based chemotherapy to carboplatin-based chemotherapy in NSCLC (Avoid Acronyms in title) 

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A randomized controlled trial comparing the efficacy and toxicity of cisplatin-based chemotherapy to carboplatin-based chemotherapy in NSCLC (Avoid Acronyms in title) 

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Aim:
To assess the efficacy and toxicity of cisplatin-based chemotherapy when compared with carboplatin-based chemotherapy in patient with NSCLC
Objectives:
1. To identify the intensity and frequency of nausea and vomiting between cisplatin-based chemotherapy and carboplatin-based chemotherapy in NSCLC patient
2. To establish the relationship of the efficacy and overall survival rate of cisplatin-based chemotherapy to carboplatin-based chemotherapy in NSCLC patient

Mei Qi

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Please correct the mistakes: To- to be written as To(T capital
Aim:to study the direct relation of gene on producing of cancer.
Object:every one can be a victim of this disease.How we can know the effect of this factor?

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Correct the following mistakes in your proposal writing

1. Write your name or roll number

2. Avoid the acronyms in the title (e.g. NP).

3. Remove the (.) In the aim and objectives started with the word “ To”

4. Use title caption from writing the Title Eg: An Overview of Polyamidoamine Dendrimers

5. Reflect your title with aim, objectives, research question and problem of the statement.

6. Sample Research Questions

a. Can changes in diet and upbringing

compensate for genetic abnormalities?

b. In what ways is brain development

affected by experience?

c. When do children become aware that other people have thought  processes of their own, and what makes this awareness possible?

d. Why is there little pretend play among young children in many societies, and what difference does this make in later development?

e. What causes some children to be bullies?

Best Wishes

Dr. Vijay

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Title: Controlled trial in managing menopause symptoms after breast cancer 

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Title: Controlled trial in managing menopause symptoms after breast cancer 

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Aim: To determine the appropriate management for menopause symptoms after breast cancer
Objectives: 1. To assess the evidence based guidelines and expert opinions from professional studies in the management of menopause symptoms after breast cancer.
2. To find out the effect of using SERM and TSEC agent in managing menopause symptoms.
3. To find out the effect of lifestyle intervention instead of hormone replacement therapy in resolving menopause symptoms.

Nithya

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Title: The utilization of Rituximab in addition to CHOP chemotherapy as standard treatment of patients diagnosed with non-hodgkin's lymphoma

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Title: The utilization of Rituximab in addition to CHOP chemotherapy as standard treatment of patients diagnosed with non-hodgkin's lymphoma

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Aim: To determine the first line treatment plan for non-hodgkin's lymphoma patients in Malaysia.

Objective:
1) To explore the effect of rituximab together with CHOP chemotherapy on quality of life, overall survival rate and relapse rate of non-hodgkin's lymphoma patients.
2) To identify the therapeutic efficacy and possible side effects of rituximab in lymphoma patients.
3) To access the cost effectiveness of adding rituximab to chemotherapy for treatment of non- hodgkin's lymphoma patients.

Research question:
1) Should rituximab, a monoclonal antibody be used together with CHOP chemotherapy for treatment of newly diagnosed non-hodgkin lymphoma patients?

Research problem:
The incidence of non-hodgkin's lymphoma is rising worldwide. Statistical records from the National Cancer Registry 2007 of Malaysia show that lymphoma is the sixth most common cancer among Malaysians with a higher occurence among Chinese compared to Malays and Indians. Non-hodgkin's lymphoma has a significant clinical heterogeneity and the pattern and frequency of this disease varies widely requiring treatment strategies to be tailored accordingly to the individual patient condition. Furthermore despite early diagnosis and major therapeutic advances, there are still patients that relapse or remain refractory to treatment provided. Currently, a novel monoclonal antibody rituximab is being employed in treating this disease together with standard chemotherapy. Further investigation is needed to determine the appropriateness of adding rituximab to chemotherapy in regards to patient's quality of life, survival and relapse rate.

Chang Lina
1000819502

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A cohort study: Consumption of Monosodium Glutamate (MSG) on Cancer

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A cohort study: Consumption of Monosodium Glutamate (MSG) on Cancer

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Aim: To assess the effect of monosodium glutamate (MSG) on development of various cancer.

Objectives:
1. To identify the effect of MSG on cancer.
2. To establish the relationship between amount of MSG consumed and development of various cancer
3. To identify types of cancer most likely associated with consumption of MSG.

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A Novel Diagnostic Protocol for Lung Cancer

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A Novel Diagnostic Protocol for Lung Cancer

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Problem Statement:
Lung cancer remains as the leading cause of cancer-related
death worldwide, mainly due to late diagnosis. Up to date, there's no diagnostic kit/device with high sensitivity available for detection of lung cancer at early stages.
Aim:
To get an early diagnosis of lung cancer through blood analysis.
Objectives:
1. To identify the particular compounds which released by lung tumors in blood circulation through blood analysis.
2. To characterize the chemical/genetics properties of these compounds.
3. To design a detection kits with high sensitivity for these compounds based on their chemical/genetics properties.

Marwan Maki

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Dr. Vijay                      Cancer: The failure of treatment

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Dr. Vijay                      Cancer: The failure of treatment

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Aim:
Objects:

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A cohort study: Endometrial cancer results from oral contraceptive pill (OCP) intake in Australia women.

Aim: To investigate the relationship between oral contraceptive pill intake and endometrial cancer.

Objectives: To assess the frequency of OCP intake among women with endometrial cancer vs women using other contraception methods in Australia.

Alice Ew