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It not clear who invented the first microscope, but the Dutch spectacle maker is credited with making one of the earliest compound microscopes (ones that used two lenses) around 1600. The earliest microscopes could magnify an object up to 20 or 30 times it’s normal size !

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Researchers invented a new type of microscope called reflective matrix microscope, which uses adaptive optics techniques. Non-invasive microscopic techniques such as optical coherence microscopy and two-photon microscopy are commonly used for in vivo imaging of living tissues

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Divini's Vase Microscope - This Italian-style vase microscope was made by Eustachio Divini in the late 1600s and was used in pioneering biological studies by Marcello Malpighi.

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https://www.youtube.com/watch?v=c_BiLl2v6OE

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The 19th century brought major improvements to microscopes, including achromatic lenses, which allowed viewers to see color accurately for the first time. There were also new ways to illuminate specimens and control light, and the bases of compound microscopesbecame more stable