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We can then guess that around 110 billion humans have lived over the past 52,000 years, that means that around 50 billion would have needed to have died from Malaria, a rate of very roughly 5 ½ million per year from 800 BC to 1900 AD, for this factoid to be true. We only have reliable data on deaths from 1900 until present.[2]

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How we conquered the deadly smallpox virus - Simona Zompi

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Cost of Disease

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What is the difference between the endemic level of a disease, an epidemic, and a pandemic? Please pardon my amateur narration, an updated version is forthcoming with new narration.