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The brain controls our whole body and damage to it would kill us. Therefore, shooting a zombie in the brain is the way to kill it. The best place to shoot a zombie would be the frontal lobe. The frontal lobe is the area of the zombie brain that still has limited function and this would be the best place to shoot the zombie to ensure it is "dead."

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The hypothalamus is the coordinator for the regulation of food intake and is located under the midline of the brain, behind the eyes: Within the hypothalamus are nerve cells that, when activated, produce the sensation of hunger.

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The prefrontal cortex is responsible for stimulus-locked attention. This part of the brain controls most of our cognitive functions and takes control of the brains attention.

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The central amygdala is the part of the brain that is effected by diminished pain perception and plays a central role in physiological and behavioral responses to fearful stimuli, stressful stimuli, and drug-related stimuli.

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The left frontal lobe or the Broca's area, is the part of the brain that is effected by language deficit. It is near the motor cortex and utilized in speech production, located in the inferior frontal gyrus. This area regulates breathing patterns while speaking and vocalizations required for normal speech.

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The part of the brain that long-term memory loss effects is the hippocampus and cortex. The hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. The cerebral cortex, which is the outer surface of the brain, is associated with higher level processes such as consciousness, thought, emotion, reasoning, language, and memory

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The cerebellum is involved in many functions such as language, sensations, memory, learning, etc. The cerebellum is classically described as a motor coordination region.

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The orbitofrontal cortex is known to inhibit the amygdala, which is involved with the fight-or-flight response. Therefore, a damaged orbitofrontal cortex, paired with a strengthened amygdala, might replicate the aggressive behaviors of a zombie.