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Duchenne's Muscular Dystrophy (DMD)

sex-linked recessive disease

found on the X chromosome

shows complete dominance

Interesting Fact - It was recently (late Oct. 2019) reported that a new gene therapy is able to safely prevent muscle deterioration in mice and dogs with the DMD mutation.

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Achromatopsia (Color Blindness)
Sex-linked recessive disease
-Found on X chromosomes
-Complete dominance

Interesting Fact: It's estimated that there are 300 million color blind people in the world!

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Hemophilia
- sex-linked recessive disease
- found on the X chromosome
- shows complete dominance
Interesting Fact- There are 3 types of Hemophilia, Hemophilia A, Hemophilia B, and Hemophilia C. Each are caused by a different deficiency factor.

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Sickle Cell Disease

Sickle Cell Disease is carried on an autosomal chromosome.

The trait can be used to demonstrate the concepts of co-dominance and incomplete dominance.

Interesting Fact:
Sickle cell disease is curable by bone marrow transplants.

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Hereditary Hemochromatosis

It is where there is an excess amount of iron in the body.
-Autosomal recessive
-Complete dominance
Fun fact: Most people with hemochromatosis are diagnosed between the ages of 30 and 50. About 75% of them have no symptoms.

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1. Osteogenesis Imperfecta has an  autosomal dominant pattern of inheritance.
2.  Found on X chromosome.
3.  Incomplete dominance
Interesting Fact; There are 8 types of OI recognized by the medical community ranging from undetectable to fatal.

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Cystic Fibrosis
-Sex linked recessive
-autosomal-found on chromosome 7
-complete dominance
Fact-cystic fibrosis is the most common genetic disease in north america

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Sickle Cell Anemia
-Autosomal recessive
-Chromosome 11
-incomplete dominance
-fun fact: celebrity Paul Williams died from sickle cell anemea.

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Ryan S                                            Albinism

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Ryan S                                            Albinism

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-Autosomal  recessive or Sex linked on the X chromosome
-Complete dominance
-Fun fact: There are two types of Albinism, OCA and OA. One type of OA is sex linked.

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Huntington's Disease
- Autosomal dominant
- Chromosome 4
- Incomplete dominance
Interesting Fact: Everyone has the gene for HD, but only those who inherit the expansion of the gene will develop it.

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Cancer
-Autosomal Dominant
-Incomplete dominance
-Interesting Fact: The most frequent types of cancer differ between men and women.

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Down syndrome
- Autosomal recessive
- Chromosome 21
- Multiple alleles, incomplete dominance, and codominance are what make up down syndrome.
- A person with down syndrome has many copy's of the same chromosome (chromosome 21) this is why there are many makeups of this  disorder.

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polymelia
- occurs in humans and other animals
- Is a birth affect that the affected organism has more than the usual number of limbs
-with reports in buffalo, chickens, frogs, and even people
- Fun facts

There are different types of polymelia

You cannot move the extra limbs.

Ounce the extra limbs are amputated you can move your limbs normally.

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-Eye color is an inherited trait on the X chromosome (number 15)
-Example of complete dominance (Brown eyes)
-Interesting fact: Humans can have violet eyes.

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Heterochromia
- Autosomal Dominant
- Complete dominance
- It does not affect visual acuity

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Diabetes
Autosomal Dominant
Complete dominance
Diabetes is the 7th leading cause of death in the US

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Autosomal
Codominance
Almost never causes problems

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-Charcot-Marie-Tooth disorder
-Autosomal Dominant
-Complete dominance
-One of the most commonly inherited disorders

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Sickle Cell Anemia

- It is autosomal
- It can be found on Chromosome 11
- It is incomplete dominance
Fun Fact: For some patients this disease can be cured. It is through bone marrow transplant which can be super risky.

(the picture wont load so here is the link)
https://www.google.com/url?sa=i&url=https%3A%2F%2Fwww.gethealthystayhealthy.com%2Farticles%2Fsickle-cell-trait-vs-sickle-cell-disease&psig=AOvVaw2jCQ-kKcorWpEv7XiGDCPw&ust=1616883404359000&source=images&cd=vfe&ved=0CAIQjRxqFwoTCJjx-5r-zu8CFQAAAAAdAAAAABAD

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1. OI has a pattern of being autosomal dominant
2. It is found on the x chromosome
3. Incomplete dominance
4. OI is a connective tissue disorder that affects between 20,000 and 50,000 Americans.