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Oral and Intravenous
Therapeutic Class: Loop Diuretic
MJ

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Oral and IV: 20mg initial dose, increase to achieve desired effect.
IV usually 1mg/mL or 2mg/mL
- Administer 20-40mg per minute to reduce risk of ototoxicity
Administer orally with or without food
MJ

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Image from: https://www.medgadget.com/2021/07/loop-diuretics-market-growth-opportunities-business-outlook-and-forecast-to-2030.html

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Before:
• Allergies - Sulfonylurea
• Renal function
• Electrolyte abnormalities (esp. Potassium)
• Blood pressure

During:
• Orthostatic hypotension
• Cardiac changes
• Chest pain
• Monitor blood sugar

After:
• Urine output
• Electrolyte abnormalities
MH

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Antihypertensive

Loop Diuretic

Edema

Secondary to Heart Failure

Ascites

Renal disease

MJ

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Oral:
• Begins: 30-60mins
• Peak: 1-2 hrs
• Eliminates: Depends on renal function. 2-9 hrs.

IV:
• Begins: 5 mins
• Peak: 30 mins
• Eliminates: Depends on renal function. ~2hrs.
MJ

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• Acute kidney injury
• Fluid & electrolyte abnormalities
• Hypersensitivity reaction
• Hypotension
• Ototoxicity
• Stevens Johnson Syndrome or Toxic Epidermal Necrolysis
MH

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The nurse is monitoring a patient taking furosemide for heart failure. Which electrolyte imbalance should the nurse be alert for?

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The nurse is monitoring a patient taking furosemide for heart failure. Which electrolyte imbalance should the nurse be alert for?

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A. Hyperkalemia
B. Hypernatremia
C. Hypokalemia
D. Hyponatremia

MH

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- Inhibits reabsorption of sodium and chloride in renal tubules and interferes with the chloride-binding cotransport system
MJ

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Lexicomp. (2022). Furosemide.
https://online-lexi-com.proxygw.wrlc.org/lco/action/home/

MJ MH