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Hemophilia B: information on support groups (Lesslie)

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Hemophilia B: information on support groups (Lesslie)

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Forest Institute for Regenerative Medicine hope that if their approach isn’t successful at curing the disease, it would at least solve the antibody problem so that current treatment would be effective.

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Hemophilia B: What is the current research status on hemophilia B? (Lesslie)

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Hemophilia B: What is the current research status on hemophilia B? (Lesslie)

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Currently there is no cure for Hemophilia but scientist are working to find better ways on administering cells along with finding ways to treat it.

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Hemophilia B: Long Term Outlook?           (Lesslie)

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Hemophilia B: Long Term Outlook?           (Lesslie)

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Hemophilia B can cause long terms effects like:

seizures

paralysis

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https://www.hemob.org/faq

https://www.wfh.org/en/abd/carriers/carriers-prenatal-diagnosis-en

https://www.hemophilia.ca/what-is-hemophilia/

https://www.cdc.gov/ncbddd/hemophilia/facts.html

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Hemophilia B: Which population is affected?(Briana) 

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Hemophilia B: Which population is affected?(Briana) 

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Hemophilia is the second most common type of Hemophilia. This affects about one of every 30,000 males.

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Hemophilia B: What are the symptoms or effects of Hemophilia B? (Briana)

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Hemophilia B: What are the symptoms or effects of Hemophilia B? (Briana)

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Bleeding into joints with associated pain and swelling.

Blood in the urine or stool.

Bruising.

Gastrointestinal tract and urinary tract bleeding.

Nosebleeds.

Prolonged bleeding from cuts, tooth extraction, and surgery.

Bleeding that starts without cause.

The causes are that when you bleed, multiple reactions take place in the body which cause blood clots. This is called coagulation cascade. Hemophilia B is caused mostly by the missing protein, factor IX.

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Hemophilia B: Are there prenatal tests Hemophilia?(

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Hemophilia B: Are there prenatal tests Hemophilia?(

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The are only to common ways on how to test to see if an expecting mother's child may carry Hemophilia. This can be offered by procedures such as amniocentesis or chorionic villus sampling. However, CVS can be a risk for a miscarriage. Amniocentesis is tested by small amounts of amniotic fluid being removed using a small needle. The needle is inserted in the uterus through the abdomen. This procedure is done under ultrasound guidance. Chorionic villus sampling is tested under anesthesia. "A needle inserted into the abdomen through the vagina to take a sample of chorionic villi cells from the placenta."

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Hemophilia B: What gene or chromosome is affected? (Briana)

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Hemophilia B: What gene or chromosome is affected? (Briana)

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The factor IX gene is located on the X chromosome. As a result, it is commonly only in males. Generally, the disorder is caused because of the loss of the factor IX gene.

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Hemophilia B: What causes the  disorder?(Briana)

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Hemophilia B: What causes the  disorder?(Briana)

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Hemophilia is usually caused by some missing proteins. These proteins are a part of the system that causes the blood to clot. Specifically in Hemophilia B, the missing protein is factor IX. This affects to males exclusively. Factor IX is one of the 13 clotting factors.

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Hemophilia B: What are the different nicknames for this disorder?(Briana)

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Hemophilia B: What are the different nicknames for this disorder?(Briana)

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There are two names for Hemophilia.

Classical Hemophilia because it is the most common case of Hemophilia.

Factor VIII deficiency hemophilia, because it does not have the factor 8 protein in the blood that causes the clotting problem.