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Image: Henrietta Lacks: 31-year-old African American Woman

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Image: Henrietta Lacks: 31-year-old African American Woman

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Not all heroes have clout. Not all who contribute to science are scientists. Today we recognize, celebrate and thank Henrietta Lacks.

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Cells divide to make more cells. This is how we grow and how old or damaged cells get replaced. Cancer is when cells grow uncontrollably.

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We need to understand what was happening in Henrietta Lacks' body that led her to walk into Johns Hopkins Hospital. Click the link to see an interactive module of the cell cycle (both in normal cells and cancerous cells). This will give you a better idea of how cancer develops.

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This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.

Students can toggle between two different views of the cell cycle by pressing the text in the center of the graphic. The “Cell Cycle Phases” view describes the cell cycle phases and checkpoints, and includes illustrations of the cell’s chromosomes. This view is appropriate for all levels of high school biology. The “Cell Cycle Regulators and Cancer” view explains the protein regulators, their roles in cell cycle progression, and how mutated versions can lead to cancer. This view may be more appropriate for AP/IB Biology and introductory college biology.

The accompanying worksheets guide students’ exploration. The “Overview Worksheet” is intended to provide an introduction to the cell cycle as it relates to cancer. For a more comprehensive review of the cell cycle and the molecules that regulate each phase, use the “In-Depth Worksheet.”

The “Resource Google Folder” link directs to a Google Drive folder of resource documents in the Google Docs format. Not all downloadable documents for the resource may be available in this format. The Google Drive folder is set as “View Only”; to save a copy of a document in this folder to your Google Drive, open that document, then select File → “Make a copy.” These documents can be copied, modified, and distributed online following the Terms of Use listed in the “Details” section below, including crediting BioInteractive.

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This interactive module explores the phases, checkpoints, and protein regulators of the cell cycle. The module also shows how mutations in genes that encode cell cycle regulators can lead to the development of cancer.

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HeLa Cells

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SlideShow: Ethics In Scientific Research

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SlideShow: Ethics In Scientific Research

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Essential Question: What do you think is more important? The needs of scientific research or the ethical rights of individuals?

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Henrietta Lacks: Her DNA Fueled Medical Breakthroughs

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Henrietta Lacks: Her DNA fueled medical breakthroughs

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Please use the following rubric to guide you as you consider your evidence and write your CER.

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Scholastic Science World

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HeLa Cells Timeline