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Arthur Newman Official US Release Trailer

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Meeting Obama Made John Krasinski & Emily Blunt Lose Their Minds

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Jimmy Kimmel Auditions for Every Matt Damon Role

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Please donate at http://www.end7.org/ENDthis We asked celebrities including Emily Blunt, Eddie Redmayne and Priyanka Chopra to watch a powerful new video. See how they reacted to people suffering from neglected tropical diseases (NTDs)...Can you make it through to the end? Visit http://www.end7.org to join the fight.

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Manchester Science Festival is proudly produced by MOSI

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Manchester Science Festival is proudly produced by MOSI

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Check out other Manchester Science Festival Events

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Check out other Manchester Science Festival Events

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@mancimmunogroup

@immunojo

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The latest Tweets from MancImmunoGroup (@MancImmunoGroup). Manchester Immunology Group (MIG) Our research addresses key questions such as how our immune system responds to infection and regulates inflammation. University of Manchester

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Read about our recent research with local school children here

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Pupils from inner-city Manchester have been working with scientists at The University of Manchester to carry out research into a condition which affects around one billion people worldwide.

The 29 youngsters from Trinity Church of England High School in Hulme, conducted an eight-week experiment with scientists from the University's Institute of Inflammation and Repair looking at the development of eggs from worms that infect your gut.

The pupils learnt how worm eggs infect children around the world, hatching inside the gut and causing malnutrition and sickness. Infections can make children so ill that they miss out on important education.

In their experiment, the pupils treated worm eggs with different substances to try and stop eggs developing into worms, to stop the spread of disease.

They found for the first time that clove oil, a natural product which grows in many areas where worm infections are common, stopped egg development by 50%. This means that clove oil has the potential to be a natural therapy and reduce the spread of worm infection. Pupils then created posters showcasing their results, and took part in a presentation day with parents, staff and students from the University, 24 large pizzas and 150 pieces of cake!

Dr Jo Pennock, from the Institute of Inflammation and Repair, said: "Most of the children and their parents had never been to the University before and didn't know very much about what scientists did. We hope that by working more closely with local children, we'll inspire and encourage them to take up science, both as a subject choice but also as a career.

"Actually by the end of the project a quarter of them had changed their mind about scientists in general, which is always a plus!''

All pupils received a certificate for participation and prizes were awarded, presented by Professor Richard Grencis from the University's Faculty of Life Sciences. The project was funded by a Royal Society Partnership grant between Dr Catherine Alnuamaani from Trinity Church of England High School, and Dr Pennock.

Ann Flatman, Deputy Headteacher at Trinity Church of England High School, said: "The Trinity Community are extremely proud of our pupils and the work they have carried out during the Royal Society Research Project. It is a joy to see pupils engaged and learning practical scientific skills. As a church school it is extremely important to us that our pupils gain a real understanding of the hardships faced by others within our global community. The fact that they have stumbled across a potential solution to a condition that affects millions of other children world wide is an added bonus, to say the least".

Parent Alison Steadman, from Hulme, said: "I've lived in Manchester all my life but I've never been inside the University. This has been a fantastic day."
The University team now hopes to secure additional funding from the Gates Foundation to further this research and understand how clove oil could potentially treat these infections.

ENDS

Notes for editors

For further information, please contact: Alison Barbuti | Media Relations Officer | Faculty of Medical and Human Sciences |The University of Manchester
Tel. +44 (0)161 275 8383 Mobile 07887 561 318 |Email: alison.barbuti@manchester.ac.uk

Images of pupils:
Microscope1: Maryam Nikdel Mazinan
Microscope2: Maren Fulton and Rebecca Cowtan
Microscope 3: Jordan Black, Henry Lam, Ryiad Mustafa

The Royal Society is a self-governing Fellowship of many of the world's most distinguished scientists drawn from all areas of science, engineering, and medicine. The Society's fundamental purpose, as it has been since its foundation in 1660, is to recognise, promote, and support excellence in science and to encourage the development and use of science for the benefit of humanity.
The Society's strategic priorities emphasise its commitment to the highest quality science, to curiosity-driven research, and to the development and use of science for the benefit of society. These priorities are:
Promoting science and its benefits
Recognising excellence in science
Supporting outstanding science
Providing scientific advice for policy
Fostering international and global cooperation
Education and public engagement

The Royal Society provides strategic and independent advice to the Government, its agencies and key opinion-formers, with the aim of improving science and mathematics education in schools and colleges across the UK. Our key goals are to ensure that we have a science literate public and to inspire as many young people as possible to study science and mathematics post-16.

The Partnership Grants scheme offers up to £3000 of funding for schools who, through working in partnership with scientists or engineers, develop and deliver exciting and creative projects to engage young people with science. They allow teachers to increase their scientific knowledge and give scientists and engineers the opportunity to develop their communication skills, and engage with enquiring young minds. Most importantly, these projects give school students a taste of science and engineering today, and their relevance for society.

Pupils from inner-city Manchester have been working with scientists at The University of Manchester to carry out research into a condition which affects around one billion people worldwide.

The 29 youngsters from Trinity Church of England High School in Hulme, conducted an eight-week experiment with scientists from the University's Institute of Inflammation and Repair looking at the development of eggs from worms that infect your gut.

The pupils learnt how worm eggs infect children around the world, hatching inside the gut and causing malnutrition and sickness. Infections can make children so ill that they miss out on important education.

In their experiment, the pupils treated worm eggs with different substances to try and stop eggs developing into worms, to stop the spread of disease.

They found for the first time that clove oil, a natural product which grows in many areas where worm infections are common, stopped egg development by 50%. This means that clove oil has the potential to be a natural therapy and reduce the spread of worm infection. Pupils then created posters showcasing their results, and took part in a presentation day with parents, staff and students from the University, 24 large pizzas and 150 pieces of cake!

Dr Jo Pennock, from the Institute of Inflammation and Repair, said: "Most of the children and their parents had never been to the University before and didn't know very much about what scientists did. We hope that by working more closely with local children, we'll inspire and encourage them to take up science, both as a subject choice but also as a career.

"Actually by the end of the project a quarter of them had changed their mind about scientists in general, which is always a plus!''

All pupils received a certificate for participation and prizes were awarded, presented by Professor Richard Grencis from the University's Faculty of Life Sciences. The project was funded by a Royal Society Partnership grant between Dr Catherine Alnuamaani from Trinity Church of England High School, and Dr Pennock.

Ann Flatman, Deputy Headteacher at Trinity Church of England High School, said: "The Trinity Community are extremely proud of our pupils and the work they have carried out during the Royal Society Research Project. It is a joy to see pupils engaged and learning practical scientific skills. As a church school it is extremely important to us that our pupils gain a real understanding of the hardships faced by others within our global community. The fact that they have stumbled across a potential solution to a condition that affects millions of other children world wide is an added bonus, to say the least".

Parent Alison Steadman, from Hulme, said: "I've lived in Manchester all my life but I've never been inside the University. This has been a fantastic day."
The University team now hopes to secure additional funding from the Gates Foundation to further this research and understand how clove oil could potentially treat these infections.

ENDS

Notes for editors

For further information, please contact: Alison Barbuti | Media Relations Officer | Faculty of Medical and Human Sciences |The University of Manchester
Tel. +44 (0)161 275 8383 Mobile 07887 561 318 |Email: alison.barbuti@manchester.ac.uk

Images of pupils:
Microscope1: Maryam Nikdel Mazinan
Microscope2: Maren Fulton and Rebecca Cowtan
Microscope 3: Jordan Black, Henry Lam, Ryiad Mustafa

The Royal Society is a self-governing Fellowship of many of the world's most distinguished scientists drawn from all areas of science, engineering, and medicine. The Society's fundamental purpose, as it has been since its foundation in 1660, is to recognise, promote, and support excellence in science and to encourage the development and use of science for the benefit of humanity.
The Society's strategic priorities emphasise its commitment to the highest quality science, to curiosity-driven research, and to the development and use of science for the benefit of society. These priorities are:
Promoting science and its benefits
Recognising excellence in science
Supporting outstanding science
Providing scientific advice for policy
Fostering international and global cooperation
Education and public engagement

The Royal Society provides strategic and independent advice to the Government, its agencies and key opinion-formers, with the aim of improving science and mathematics education in schools and colleges across the UK. Our key goals are to ensure that we have a science literate public and to inspire as many young people as possible to study science and mathematics post-16.

The Partnership Grants scheme offers up to £3000 of funding for schools who, through working in partnership with scientists or engineers, develop and deliver exciting and creative projects to engage young people with science. They allow teachers to increase their scientific knowledge and give scientists and engineers the opportunity to develop their communication skills, and engage with enquiring young minds. Most importantly, these projects give school students a taste of science and engineering today, and their relevance for society.

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Pupils discover new treatment to stop the spread of worm infection | The University of Manchester

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Pupils from inner-city Manchester have been working with scientists at The University of Manchester to carry out research into a condition which affects around one billion people worldwide. The 29 youngsters from Trinity Church of England High School in Hulme, conducted an eight-week experiment with scientists from the University's Institute of Inflammation and Repair looking at the development of eggs from worms that infect your gut.

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2.5 billion do not have access to a clean toilet! Think of all the worm eggs!

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Page not found | Manchester Immunology Group

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Rangoli at Manchester Science Festival 2010

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Rangoli at Manchester Science Festival 2010

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Trichuris spp are one of the most successful helminths on the planet. Watch this video animation of fascinating electron microscope images of the gut to see how these worms survive in the large intestine. This video was made by the Manchester Immunology Research Group, University of Manchester, Uk.

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Richard III suffered from a roundworm infection, a team says.

A soil sample from the region where his infected intestines would have been during life, revealed multiple roundworm eggs.

Prevalent both in medieval times and in tropical countries today, the roundworm parasite spreads from faecal contamination and can grow up to one foot long.

The work is published in the Lancet journal.

In addition to soil from the pelvis, scientists tested soil from other areas of the grave to see whether the eggs were equally distributed.

"What we found was plenty of roundworm eggs in the sacral soil, where his intestines would have been. There were no parasite eggs of any kind in the skull soil and only very low levels around the grave," said Piers Mitchell, a medical consultant and researcher at Cambridge University.

"This shows that the significant number of eggs inside the soil must have genuinely been from his intestines and could not have been contamination from soil in the grave."

Who was Richard III?

Richard III was the last Yorkist king of England, whose death at the age of 32 in the Battle of Bosworth effectively ended the Wars of the Roses.

His nephews Edward V and Richard of York, the "Princes in the Tower", disappeared in 1483 and are said by many historians to have been murdered on Richard III's orders.

Shakespeare's version of events in his play Richard III added to the king's infamy, but some historians reject the heinous crimes attributed to Richard.
Find out more about Richard's reign Mad murderer or a man of his times?
Discarded human waste

Most soil from medieval times is likely to show some contamination as human waste was often discarded from windows onto the ground below.

Medieval farmers also used faeces as a crop fertiliser which could also have quickly spread the unwelcome guest.

The eggs were identified by powerful microscopes after they had been separated from the soil using sieves. In the right conditions, the dead eggs can be preserved for hundreds of years due to the robust nature of their cell walls.

Roundworms infest the human digestive tract and use the body as a host to stay alive and reproduce. As they steal their host's food, an infection could have resulted in malnutrition or death among people who had extremely poor diets.

Today it is thought a quarter of the population still suffer from roundworm, especially in tropical countries with poor sanitation.

The "king under the car park" was likely to have had an extremely nutritious diet so he may not have noticed many symptoms, apart from a dry cough.

Common parasites

Many medieval people would have suffered from other intestinal parasites present in meat and fish, but there was no evidence of these in the king's remains.

This suggests that his chefs would have cooked his food very well explained Dr Mitchell.

"Parasites are killed by the thorough cooking of meat, so medieval chefs were perhaps more conscientious than you might otherwise have guessed."

Jo Appleby, at the University of Leicester who helped uncover Richard III's skeleton, said that roundworms were very common at the time.

"It might seem surprising that Richard - who had a very noble background - was infected with roundworm, but this is something that you can pick up very easily through faecal contamination," she told BBC News.

Simon Brooker, at the London School of Hygiene and Tropical Medicine said it was very plausible Richard III had roundworm. He explained that eggs in the pelvic abdominal regions had also been found in other historic sites.

"Where you've got a large number of worms combined with poor nutritional intake, the consequences can be quite severe.

"I expect Richard III's exposure would have been low compared to the people he ruled over. It would have been somewhat of a nuisance rather than having had any severe consequences," Prof Brooker told BBC News.

In February 2013 a team from the University of Leicester said DNA from the bones matched that of descendants of the monarch's family. Since then his distant relatives have been granted a review over the decision to bury his remains in Leicester.

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Richard III suffered from a roundworm infection, a team says. A soil sample from the region where his infected intestines would have been during life, revealed multiple roundworm eggs. Prevalent both in medieval times and in tropical countries today, the roundworm parasite spreads from faecal contamination and can grow up to one foot long.

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Over 1.5 billion people are infected with intestinal worms

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Over 1.5 billion people are infected with intestinal worms

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That's 24% of the world's population!

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