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Neisseria gonnorrhoeae

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Nesseria gonorrhoeae

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This human pathogen is a gram-negative, flattened cocci, arranged as diplococci. It is identified by the gram-negative diplococci in the neutrophils. Gonoccoccus tends to remain alive after being engulfed by neutrophils, their appearance in urethral, vaginal, cervical, or eye exudates is presumptive evidence of infection. The disease can be confirmed by biochemical and DNA testing. This pathogen is also very rarely motile and non-spore-forming.

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Genital gonorrhea

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This is a strictly human infection, N. gonorrhoeae is an obligate parasite and may be found in the mucosal cells of the genitourinary tract, eye, rectum, and throat.

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In males, this infection can lead to urethritis and painful urination. While in females, the infection can cause pelvic inflammatory disease and ectopic pregnancy.

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Females: increased vaginal discharge, painful urrination, painful intercourse, abdominal or pelvic pain.
Male: greater urge to urinate, a pus-like discharge from end of the penis, swelling or pain in testicles, and a persistent sore throat.

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Because of widespread resistance to a growing list of antimicrobial, the only recommended treatment for N. gonorrhoeae infection is dual therapy with ceftriaxone and azithromycin. A large proportion of gonorrhea infections are complicated by infections with another sexually transmitted disease, and multi-drug treatment has the added benefit of generally resolving these infections as well.

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Controlling the disease depends on the emphasis of safe sexual practices such as the use of condoms.