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Nursing implications and nursing diagnoses

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Nursing implications and nursing diagnoses

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Assess for penicillin allergy in each patient who will be receiving
-If history of mild reaction, consult provider to consider cephalosporin
-If history of anaphylaxis, AVOID administration of penicillin or cephalosporins
-Observe patients at least 30 minutes after any PCN injection

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- Patients should take the full treatment of this drug.
- Patients should not stop the drug once they feel better.

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-Penicillin G: not stable in stomach acid and must be given parenterally
-Penicillin V: stable in stomach acid and may be given orally and taken with meals

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Aminoglycosides
-increases bactericidal effects
-PCN weaken cell wall so aminoglycosides can enter
-PCN can inactivate aminoglycosides, never mix in the same IV solution! Must space administration of the two antibiotics

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-Allergy (PCN are the most common cause of drug allergy)
-Pain at injection site (prolonged but reversible)
-Sensory and motor dysfunction (if injected into a peripheral nerve)
-Neurotoxicity (if blood levels are too high)

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- excreted through the renal system (Urine)

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-Most non-penicillinase-producing gram positive bacteria (Streptococcus species)
-Gram negative cocci (Neisseria species)
-Anaerobic bacteria
-Spirochetes (Treponema pallidum - Syphilis)

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Pharmacologic actions and therapeutic effect 

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Pharmacologic actions and therapeutic effect 

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-Weakens the cell wall of bacteria undergoing growth and division, causing the bacteria to take up excessive water and rupture
-Bactericidal --> kills bacteria

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Antibiotic