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HIV is a very serious disease where a virus infects immune cells and then uses their DNA in order to make copies of itself, and spread the virus. When having this virus it may lay dormant within your cells until one day it activates and causes you a world of pain. The antiretroviral medications can make this virus become dormant, but the second a patient stops taking it then their symptoms will return. However, scientists have been using the Nobel Prize Winning technology known as Crisper in order to remove the HIV gene from within the infected cells. This tool acts like a pair of scissors which can cut out the unwanted section of DNA which has been infected with the HIV virus. The research team for the University of Amsterdam is one of the research teams which discovered this process. However, they only classified this as proof that there is a cure, but it isn’t a reality yet. The other scientists which have attempted this process have experimented with three patients. After 48 weeks they had no long term side effects, and in general it is very complicated to remove this gene from every infected cell in the human body. If there were complications where extra genes were removed then it could end up harming the patient and leaving long term side effects. Throughout many years and trials hopefully one day this cure can help thousands of patients live a happy and healthy life.

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Scientists say they can cut HIV out of cells

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The gene-editing method used might ultimately offer a way to remove HIV, experts say.

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A Paris company named Kering says Gucci sales may drop 20% in the first quarter due to the Asia downturn. The luxury market grew in the last decade, but recent sales weren't so strong. Around 33% of Gucci sales come from China, where economy has struggled. The company will release financial results on April 23. Gucci is known for targeting younger, ambitious customers who can be more impacted by money troubles.

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Gucci sales to fall by 20% due to Asia slowdown

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It is estimated to get more than a third of its sales from China, whose economy has been struggling.

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Alaska Airlines is being sued by Cuong Tran, a Californian who recently boarded a flight with the company and sustained injuries due to a plane malfunction. As the flight made its way over Portland, Oregon, an unused door next to the row in front of Tran's seat came unhinged and flew off the side of the plane, leaving Tran and surrounding passengers exposed to the outer extremities at 16,000 feet above ground. The four bolts that held this door in place had been worked on late last year, however there is no record of the individual who completed this apparently faulty work. Although the exact cause of the door coming dislodged is still being investigated, it appears to be that the bolts were unable to withstand the increasing air pressure that came with the ascension of the plane, and thus came unscrewed, leading to the displacement of the door. No deaths resulted from this incident, although Tran specifically received minor lacerations to his lower leg. This lack of physical trauma, however, does not constitute to a lack of emotional trauma. Tran had his phone, socks, and shoes ripped away from him, and if it hadn't been for his seatbelt, he too would have been ripped out of the plane. All passengers on the plane had to wear the deployed oxygen masks until a safe elevation was reached, and the thirty minutes that it took for the plane to land was a nightmare for all on board. Tran is not the only one taking legal action against the flight company, as several other passengers present on the flight are suing for the emotional distress and anxiety that they have experienced as a result of the incident. Alaska Airlines has declined to comment on the incident at this time, and further investigation will provide more answers regarding the cause of the malfunction, the course of legal action against the company, and more.

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Cuong Tran next to the gaping hole after landing

A Californian man has described "holding on for dear life" as he sat on an Alaska Airlines flight inches away from a gaping hole which appeared when an unused door flew off mid-flight.

Cuong Tran told the BBC his seat belt saved him as his phone, socks and shoes were ripped off by an uncontrolled decompression 16,000ft above Portland.

He is among seven passengers to have filed a lawsuit against Boeing, Alaska Airlines and Spirit AeroSystems.

The companies declined to comment.

Images shared online - and later by the National Transportation Safety Board (NTSB) - showed a wide hole in the side of the Boeing 737-9 Max aircraft, with oxygen masks dangling from the ceiling on 5 January.

In a preliminary investigation US regulators found four critical bolts - meant to hold the so-called door plug in place - were missing from the flight which was bound for Ontario, California.

Watch: 'Trip from hell': On board flight during mid-air blowout

None of the 177 passengers and crew on-board were killed but Mr Tran, who was sitting next to his friend one row behind the section which blew out, suffered injuries including a laceration to his leg.

Speaking to the BBC, Mr Tran, 40, said it happened soon after take-off when he would usually be getting ready to doze off.

"The captain said we had passed 10,000 feet. Then the hole blew out on us and I remember my body getting lifted up. Then my whole lower body got sucked down by the howling wind."

Mr Tran said the decompression lasted around 10 or 20 seconds and he described looking around at other passengers who could not believe what was happening.

"It was probably the first time in my life I had a feeling of no control over everything. I was in disbelief over the whole situation," said Mr Tran.

Flight 1282: The Blowout

Every passenger's worst nightmare: the terrifying moment a plane door rips away mid-air.

Watch now on BBC iPlayer (UK Only)

"That feeling of no control is pretty terrifying. The suction was so strong and I was hanging on for dear life. Both my shoes ended up getting sucked out - I had my shoe on pretty tight too.

"My phone which was in my hand disappeared."

The plane was able to make its emergency landing back to Portland International Airport and passengers were seen to by emergency services.

Mr Tran added: "They said it took 30 minutes, but it felt like a lot longer.

"I had no phone so had no idea of the time, so I was just sat there staring into the hole this whole time and hoped it wouldn't get any more damage.

"That was the scariest moment - the waiting. My body is recovering, but there is a big scar in my leg. I don't know if it going to be gone any time."

Cuong Tran's shoes and socks were pulled off by the force of rapid depressurisation aboard Alaska Airlines Flight 1282

Mr Tran is one of several passengers suing Alaska Airlines, Boeing and manufacturer Spirit Aerosystems, claiming the event left them with physical injuries and "serious emotional distress, fear, and anxiety".

The plaintiffs are seeking punitive, compensatory and general damages, although the lawsuit does not specify an amount.

Spirit Aerosystems, Boeing and Alaska Airlines said it would not comment on pending litigation.

Attorney Timothy A Loranger told the BBC the litigation process could take "a couple of years" as there are a lot of people involved.

"His [Mr Tran] leg was almost sucked out of the airplane if it wasn't for his seatbelt," Mr Loranger said. "It is just terrifying."

This lawsuit was filed in King County Superior Court, Washington, and is separate to another set of passengers who are suing Alaska Airlines and Boeing for $1bn - claiming negligence.

Alaska Airlines initially grounded its 737 MAX 9 fleet of 65 aircraft. This was later followed by an Federal Aviation Administration (FAA) order for all airlines to ground the Boeing model - approximately 171 worldwide.

Aviation giant Boeing has been under heavy regulatory scrutiny with probes into the company's safety and quality standards in its production process.

On Wednesday, the NTSB said it will hold a two-day investigative hearing on the incident at the start of August.

But NTSB chair Jennifer Homendy said Boeing has been unable to produce key information about work performed on the Alaska Airlines plane before the mid-air scare.

In a letter addressed to leaders of the Senate, Homendy said the door plug which failed had been opened so rivet repair work could be done in September last year.

The work took place at Boeing's Renton, Washington, facility before delivery to Alaska Airlines on 31 October 2023.

"To date, we still do not know who performed the work to open, reinstall, and close the door plug on the accident aircraft," Homendy said.

"The absence of those records will complicate the NTSB's investigation moving forward."

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Alaska Airlines blowout: Passenger describes being on Flight 1282

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Cuong Tran says the seatbelt saved his life as a gaping hole suddenly appeared after take-off.

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Archaeologists researching in El Cano Archaeological Park in Panama have uncovered a ninth tomb, dating back to 700, this one belonging to a religious leader of high status. This site is known for its pre-Columbian discoveries and lavish burial tombs of the era. This ninth tomb belongs to a man of high status, placed in the center of the tomb, indicated by his physical position and the artifacts that were found with him. This man was likely 30-40 years old and has been dubbed "the Lord of flutes", due to the abundance of animal bone flutes he was buried with. This burial site further indicates the grand importance that ancestor worship and these sacred sights held in the religious practices of this civilization. This tomb is the only one that has been found of a religious leader instead of a military one. The tomb included the bodies of others as well as many artifacts of wealth like jewelry, pottery and artifacts of religious significance. Researchers still have lots to discover at this site.

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Excavations of an archaeological site in Panama have revealed the grave of a religious leader buried over 1,200 years ago alongside a cache of gold objects - and numerous other human remains.

Researchers found the ancient tomb in El Caño Archaeological Park, a site in Coclé province known as a hotbed for pre-Columbian discoveries, particularly lavish burial chambers. The newfound enclosure, built around 700, is the ninth tomb unearthed from the park since excavation of the site began in 2008, according to a March 1 news release from Panama's Ministry of Culture.

The tombs, including the latest to be uncovered, are resting places for people who had a higher status within their societies, said Dr. Julia Mayo, the excavation's leader and the director of the El Caño Foundation, a group that studies Panama's cultural heritage through research on the archaeological site. The research team believe the person found lying at the center of the grave had higher status, indicated not only by his physical position but also gold and ceramic artifacts that surrounded the body.

The civilization of the region surrounding El Caño at the time treated the site as sacred and worshipped their "ancestors," referring tothose remembered for having done important things. "After the death of these people, (it was believed that) a constant communication was established between the ancestor and his descendants," Mayo said. "Our study (of the tombs) highlights the practice of ritual death in funerary rituals linked to (a higher) status."

The newly uncovered elite leader was likely a 30- or 40-year-old man, dubbed "Lord of the Flutes" by the archaeologists because he was entombed alongside a set of animal bone flutes that were likely used for religious ceremonies , she added.

And as researchers continued to explore the grave, they realized the Lord of the Flutes might have had quite a bit of company on his journey to the afterlife - potentially up to a few dozen companions whose remains were found buried beneath the offerings that surrounded him.

'A representation of social order'

The researchers found similar patterns among the tomb and the eight previously studied tombs that suggested the other bodies belonged to people sacrificed to accompany the dead to the afterlife, Mayo said. It appears the newly discovered remains were all buried at the same time and also had signs of a ritual death, she added.

El Caño is divided into two sectors of burial chambers: a high-status sector that holds burial chambers with multiple bodies, and a low-status sector where graves include only one body per grave, Mayo said. Excavation is not complete, so it's unclear how many bodies are within the newly discovered grave, but the other eight tombs have revealed anywhere from eight to 32 bodies.

While the other tombs held what researchers believe to be military leaders, the Lord of the Flutes was likely more of a religious leader, as the body was "buried with flutes and bells and not, as in the case of other lords found at the same site, with axes, spears and objects made with teeth of large predators. This calls attention to the importance of religion in this society," Mayo said in an email.

The excavation of the ninth tomb is expected to be complete by this time next year.

Ancient burial practices

The archaeologists found the body of the supposed religious leader buried face down and on top of the body of a woman, the release stated. The relationship the man might have had with the woman is unknown, Mayo said.

"The face-down mode of burial was common at this time period in this region, but the positioning of the male over the female individual is not," said Nicole Smith-Guzmán, the archaeology curator with the Smithsonian Tropical Research Institute in Panama City, via email.

However, she added other researchers reported the discovery of human remains dating back more than 1,000 years buried in similar positioning at a nearby site called Sitio Sierra, in the same province as El Caño. The researchers at the time speculated that the pair represented a husband and wife, but the theory remains unconfirmed.

"Nevertheless, it is likely that there was some sort of social relationship between the two individuals during life that was important to maintain in death," said Smith-Guzmán, who was not a part of either discovery.

Gold adornments cemented powerful alliances

Among the artifacts found scattered on top of the burial chamber and surrounding the Lord of the Flutes were five pectorals - a form of breastplate jewelry for the deceased - two belts made of gold beads, several gold bracelets and necklaces, as well as two earrings in the form of human figures, and a few pieces of jewelry made from animal teeth, including earrings made from the teeth of a sperm whale, according to the release.

These "exotic" materials were usually interpreted as the leader's strategies in life for getting more prestige within their territories, said Ana María Navas Méndez, an assistant professor of sociology and anthropology at Illinois State University, in an email. The ancient chiefs of Latin America would often establish political and economic relationships with leaders of nearby communities, allowing precious and artisan goods to be swapped with one another, she added.

Several of the artifacts found within the tomb were "stylistically similar to those produced in the Quimbaya region (of Colombia)," Mayo said, adding that this indicates there was a great deal of interaction and exchange of materials "between the populations that inhabited the central region of Panama and the north of South America."

City of the dead

Experts believe El Caño functioned as a regional ceremonial center or necropolis (city of the dead) for elite members of society, Smith-Gúzman said.

There have been two attempts - the most recent in 2021 - to figure out whom the various tombs found at the El Caño site once belonged to, Mayo said. But each attempt failed to pick up any DNA from the human bones, most likely because the region's hot and humid climate is not ideal for preservation, she added.

"(This discovery) offers new evidence to continue studying the chiefdoms in Panama that could be compared with previous findings," Navas Méndez said. "With this new evidence, archaeologists could ask new questions about the interactions between chiefdoms, about the political economy of pre-Columbian societies, about religious aspects, about gender, and so on."

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Gold and sacrificial victims found in tomb of ancient leader, archaeologists say | CNN

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Researchers at Panama's El Caño Archaeological Park found an ancient tomb filled with gold offerings and sacrificial victims buried to accompany a dead elite leader.

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The US government has filed a significant lawsuit against Apple, accusing the tech giant of monopolizing the smartphone market and stifling competition. The lawsuit alleges that Apple has used its control over the iPhone to limit competitors and consumer choices illegally. Apple has denied these claims and promised to vigorously defend itself. The lawsuit accuses Apple of implementing restrictive rules to hinder innovation and suppress competition. Attorney General Merrick Garland highlighted the potential negative impact on consumers and developers if Apple's actions are not challenged. The complaint lists various anti-competitive actions by Apple, including blocking certain apps, limiting third-party digital wallets, and reducing the functionality of non-Apple smartwatches. Apple has strongly opposed the lawsuit, stating that it threatens the company's core principles and ability to innovate in competitive markets.

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Watch: Apple accused of 'creating barriers' to protect iPhone
The US has filed a landmark lawsuit against Apple, accusing the tech giant of monopolising the smartphone market and crushing competition.
In the legal action, the justice department alleges the company abused its control of the iPhone app store to "lock in" customers and developers.

It accuses the firm of taking illegal steps to thwart apps seen as a threat and make rival products less appealing.

Apple has vowed to "vigorously" fight the lawsuit and denies the claims.

The sprawling complaint, filed at a federal court in New Jersey along with the attorneys general of 16 states, marks one of the biggest challenges to date for Apple, which has been fending off mounting complaints about its practices in recent years.

It alleges that Apple used "a series of shapeshifting rules" and restricted access to its hardware and software, in a bid to boost its own profits while raising costs for customers and stifling innovation.

"Apple has maintained monopoly power in the smartphone market not simply by staying ahead of the competition on the merits but by violating federal anti-trust law," Attorney General Merrick Garland said at a press conference announcing the suit.

"Customers should not have to pay higher prices because companies break the law."

The 88-page complaint focuses on five areas where Apple allegedly abused its power.

For example, the US alleges that Apple used its app review process to thwart development of so-called super apps and streaming apps, because it was worried such apps would provide less incentive for customers to stick with iPhones.

It also says Apple has made it difficult to connect iPhones to smart watches made by rivals and blocked banks and other financial firms from accessing its tap-to-pay technology, allowing Apple to earn billions in fees from processing Apple Pay transactions.

The complaint also focuses on the way Apple treats messages sent from rival phones, distinguishing them with green bubbles and limiting videos and other features. It says Apple's moves have created "social stigma" that has helped the tech giant maintain its grip on the market.

Apple said customers were loyal because they were happy and that under US law it was free to choose its business partners. It has pointed to privacy and security concerns to justify its rules.

The company said it would ask the court to dismiss the lawsuit, which it predicted would fail.

"We believe this lawsuit is wrong on the facts and the law, and we will vigorously defend against it," the company said.

The case will hinge on the question of motivation, said Bill Baer, a visiting fellow at Brookings who was an anti-trust official under the Obama administration.

"Anti-trust laws and the courts' interpretation of them suggest that once you're a monopolist," he said, "if you do engage in behaviours that have no legitimate business justification other than to limit competition and cement your monopoly, then that is problematic."

It is the third legal action Apple has faced from the US government since 2009 and the first anti-trust challenge filed against the company under President Joe Biden's administration.

If the government wins its case, it could force Apple to overhaul its current contracts and practices - or even lead to a break-up of the company.

Shares in Apple fell more than 4% as investors digested the implications of the legal battle.

Any potential changes would take years to materialise as the case makes its way through the courts.

Vanderbilt University professor Rebecca Allensworth called the case "a blockbuster", following other lawsuits the justice department has brought against the major tech giants. Google, Meta and Amazon all face similar lawsuits.

She said at its core, it was about increasing functionality between smartphones and making the technology and software more accessible to consumers and other businesses.

"It's not about breaking up Apple into small units or spinning off divisions," she said.

Apple has faced a growing legal backlash over its iOS ecosystem and business practices.

It is engaged in a lengthy legal battle with Epic Games, which makes Fortnite.

The firm had prevented streaming services from informing users of payment options outside the Apple app store, the European Commission said.

Competition commissioner Margrethe Vestager said Apple had abused its dominant position in the market for a decade, and ordered the tech giant to remove all of the restrictions. Apple said it would appeal against the decision.

Anat Alon-Beck, a business law professor at Case Western Reserve University in Ohio, said the justice department's new lawsuit was "far more extensive" than its previous legal challenges in the EU.

"It's not just about the 30% app store fee, but about the core unfair practices of Apple," she said, adding that it was "about time" that the DOJ took action.

"Apple systematically excludes rivals from the Apple ecosystem. By doing that, Apple is hurting so many startup businesses, stakeholders, customers and, in my opinion, its shareholders," she said.

According to the justice department, Apple's share of the US smartphone market exceeds 70%, and its share of the broader smartphone market exceeds 65%.

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Apple lawsuit: US accuses tech giant of monopolising smartphone market

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In a landmark lawsuit, the justice department alleges the company uses its power to limit competition.

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Research in India is proving that the extreme, increasing temperatures are having very negative effects on pregnant women. A study conducted in 2017, with 8 hundred expectant mothers showed that women working in extreme heat while pregnant are almost twice as likely to suffer stillbirth or miscarriage. In India a large amount of the job's women do involve working in extreme heat and also can be very physically demanding. Even jobs indoors can expose these women to extreme heat and be problematic. According to the study, women exposed to a great amount of heat had a 6.1% stillbirth at full term or premature birth rate and a 3% higher risk of miscarriage compared to unexposed women who had a 2.6% stillbirth at full term or premature birth rate. While temperatures are increasing all around the world, India's women are experiencing the tough reality first. It has been proven in places such as the US and Australia, that during heat waves there is a 15% rise in the risk of premature or stillbirths. Heat can clearly be a detrimental risk to soon-to-be mothers regardless of their location. This is a topic that should not be taken lightly.

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Extreme heat at work can double stillbirth risk, India study finds

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Women in India are found to be twice as likely to lose babies if they are working in hot conditions.

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Long-term sickness in the UK has reached its highest level since the 1990s, with the number of people leaving the workforce due to ill-health rising from 2.1 million in July 2019 to 2.8 million in October 2023, according to the Resolution Foundation. This is the longest sustained rise since 1994-1998. The UK is the only G7 economy not to have returned to its pre-pandemic employment rate, with inactivity figures slightly falling to 2.7 million in December 2023. The rise in long-term sickness has lasted for 54 months, with the longest previous period of increasing economic inactivity due to ill health being between 1994 and 1998. The Department of Work and Pension (DWP) has reported a 68% rise in claims for disability benefits from 2020 to 2024. The Foundation warns that failure to improve the nation's health and reduce economic inactivity could lead to wider strains on the NHS and welfare spending. The government plans to reform the Work Capability Assessment and spend £1.3bn over the next five years to help nearly 700,000 people with health conditions find jobs.

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Sick people leaving workforce at record highs

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The number of people opting out of the workforce due to long term illness is at its highest since the 90s.

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A man from Brighton by the name, Luke Young, has been off of the internet and social media for six years and claims that it would be difficult for children, teens and young adults to do the same. Young believes that there are benefits to getting the younger generation off of their phones, but can also result in some serious withdrawal effects in the minors. Many people from the younger generations turn to social media for comfort and a way to block out the world, however this cannot be healthy for them. In addition, if people could get their children away from social media, Young believes it would also keep children safer, as there are suspicious people on social media who are spying on our children and waiting for the right moment to take advantage of them. With all being said, many areas and social media sites have put restrictions on time and the content that is allowed on these sites. Many schools are banning phone usage during school hours, while some social media sites are putting the Online Safety Act to use as well. All this is being implemented, not to prevent kids entirely from having access to social media, but to increase the safety of our children and their privacy.

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Brighton offline man says smartphone ban would be difficult

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Luke Young left social media completely at 18 and says a smartphone ban would be difficult.

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In the early hours of March 25th, a peaceful and calm night turned into a horrific scene in Bailtmore, Maryland when a container ship crashed into the Francis Scott Key bridge, causing most of that famous bridge to collapse and be submerged underwater. Several vehicles, with plenty of people inside of them, were quickly plummeted into the water at freezing cold tempatures. Rescuers are currently searching for the missing people, which could be between 7 to 20 people still fighting in that frigid water.

This bridge, which was orignially built in 1977 to honor Francis Scott Key, a famous poet from Maryland, who wrote the words for the National Anthem. The bridge was 8,636ft long and spanned over the Patapsco River to the Baltimore harbour. It was the 3rd largest bridge of its type in the world.

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Baltimore Francis Scott Key Bridge collapse: What we know about ship and bridge

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How events unfolded when a cargo ship crashed into and destroyed the Francis Scott Key Bridge.

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A popular media trope is a main character that is either leading a heist themselves or trying to prevent one. In popular films such as Mission Impossible these main characters fight through security and have dramatic face offs with guards. Currently there has been accusations of damages to the British Museum but the reality is much less glamorous that media. Former Curater Dr. Peter Higgs has been accused of damaging and/or stealing $1800 of gems and other goods from the British Museum. He claims to have been unwell the day of the hearing and was not there but he has said he is fully aware of the accussations and intends to dispute them. Higgs has been accused of selling items on ebay, using psuedonyms, and falsifying documents while serving as curator of the museum. According the the writers of the linked document, "The court has also ordered Dr Higgs to share any information he has on what was sold from the collection and the items' whereabouts." The court has also requested his email and paypal records for investigation. This, if followed through, has the potential to clear up any misunderstanding. However, if it is not a misunderstanding and Higgs really did steal and damage merchandise it is unlikely that he will be very willing to share this information. In the near future Higgs' silence or honesty will be volumes to both the court and the public.

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Thief sold stolen gems to at least 45 buyers on eBay, British Museum says

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The museum launches proceedings against a former member of staff who they believe stole items.

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The royal family is facing a significant level of turmoil, as Kate Middleton speaks about her recent diagnoses with cancer. King Charles isn't out of the woods in terms of his health either, and with all the fear of health issues significantly affecting the crown, eyes are turning rapidly to Harry and Meghan. Prince Harry and Prince William have seemed to form a rift between themselves after drama with their wives became too much to deal with. Harry and Meghan stepped away from royal responsibilities but are being urged to return in light of the family health issues. Harry said that he would not return until he is met with an apology from brother Harry. During a conversation between the two brothers it was said there was very little forgiving and much more disagreement than what was originally hoped. King Charles is expected to return to duties on Easter Sunday, but he is in fact undergoing cancer treatment at this time. The British population has showed a lack of remorse for Charles however, many beyond ready for William and Kate to take to the throne, and others still upset about the life of Princess Diana.

Article Link: https://www.independent.co.uk/news/uk/home-news/kate-middleton-cancer-william-king-charles-harry-b2519352.html

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Carlos Suazo, the brother of missing Honduran soccer player Maynor Suazo, expressed hope for a miracle in finding his brother's body. The family's priority is to locate Maynor's body and then address financial concerns and informing their elderly mother in Honduras. They plan to repatriate Maynor's body to Honduras if found.

https://www.cnn.com/2024/03/27/us/baltimore-key-bridge-collapse-victims/index.html

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Holly Yan, Maria Santana, Melissa Alonso, Allison Gordon

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An international tragedy: A father of 3 and a budding entrepreneur are among 6 victims of the Baltimore bridge collapse | CNN

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They worked the overnight shift repairing potholes on a famed bridge that 30,000 Marylanders relied on every day. But early Thursday morning, a 212-million-pound cargo vessel crashed into a pillar, destroying the bridge and plunging the construction workers into the frigid water below.

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Harvard University has removed the binding of human skin from a 19th Century book kept in its library.

Des Destinées de l'Ame (Destinies of the Soul) has been preserved in Houghton Library since the 1930s. In 2014, scientists discovered that the material it was bound with was actually human skin. However, the institution has recently announced that the binding has been removed "due to the ethically fraught nature of the book's origins and subsequent history". Harvard University clarified its decision by saying: "After careful study, stakeholder engagement, and consideration, Harvard Library and the Harvard Museum Collections Returns Committee concluded that the human remains used in the book's binding no longer belong in the Harvard Library collections, due to the ethically fraught nature of the book's origins and subsequent history." Simon Chaplin, the head of the Wellcome Library, which houses books on medical history, told the BBC in 2014: "There aren't many of these books out there; it's been an occasional practice done more for generating a sense of vicarious excitement than for a practical reason." Harvard stated that its treatment of the book did not meet the "ethical standards" of care, and that in publicizing it, it utilized a "sensationalistic, morbid, and humorous tone" that was inappropriate. It apologized and stated that it had "further objectified and compromised the dignity of the human being whose remains were used for its binding".

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Harvard University removes human skin binding from book

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The book, from the mid-1880s, was reportedly bound with the skin from the body of a female patient.

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In 2016, a public health emergency was proclaimed due to the lethal opioid crisis, which led British Columbia to legalize the use of hard narcotics. In 2016, there were over 2,500 recorded overdose deaths in the province, and it is believed that 225,000 people use illegal drugs. Except in areas near schools and airports, adults are permitted to possess up to 2.5 grams of heroin, fentanyl, cocaine, or methamphetamine without being arrested, charged, or subject to a seizure under the BC program, which is in place until 2026. But locals and political opponents have been putting more and more pressure on the program, arguing that it hasn't succeeded in lowering the number of drug overdose deaths. The BC Supreme Court has halted a law that BC tabled to restrict drug use in playgrounds, residences, and places of commerce. Supporters of decriminalisation fear that public buy-in for the policy is eroding, with debates felt not only in larger cities like Vancouver but also in smaller suburbs like Port Coquitlam. Proponents of drug harm reduction say that decriminalization can save lives by lowering the risk of overdose and keeping individuals from accessing more deadly substances. In 2020, decriminalization was legalized in Oregon, although there has been opposition in Brazil, Canada, and other countries. Decriminalization proponents counter that there is no proof that drug usage in public poses a threat to the broader population. During the first year of the strategy, drug possession charges in Vancouver decreased by 76%, yet the fatality rate increased still. The departing head coroner for the province has ruled out any connection between the spike in opioid-related poisoning deaths and the decriminalization of narcotics. https://www.bbc.com/news/world-us-canada-68621012

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Success or failure? Canada's drug decriminalisation test faces scrutiny

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The test policy to help address a deadly drug crisis in British Columbia faces public backlash and political challenges.

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Germany has partially decriminalized marijuana use as of April 1st, allowing individuals over 18 to possess up to 25g in public and grow up to three plants per household. Marcel Ritschel, a supporter of the law change, plans to establish a cannabis social club. However, police unions express concerns about increased black market activity and difficulties in enforcement. Critics also worry about potential health risks and underage usage. Despite these challenges, the move reflects ongoing debates over drug policy and marks a significant shift in Germany's approach, although its longevity remains uncertain given potential political reversals.

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Cannabis decriminalised in Germany from 1 April

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Campaigners hail the law shift, which comes into force on 1 April - though police are less thrilled.