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Treatment for syphilis includes IM and/or IV antibiotic medication.

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Congenital syphilis can cause problems for your baby during pregnancy, including: neonatal death, premature birth, fetal growth restriction, anemia, problems with spleen and liver, and/or a rash on the mouth, genitals (also called sex organs) or anus, or on the bottoms of her feet and on her hands and face.

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Cardiovascular effects of late syphilis include aortic aneurysm and coronary arteritis. 

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Late: Gumma are ulcerating granulomas on skin, bone, and internal organs.

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Late Neurosyphilis, including tabes dorsalis, gait impairments, and dementia. Tabes dorsalis damages the dorsal columns and sensory nerve roots, causing a syndrome of pain and sensory deficits similar to B12 deficiency.

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Latent syphilis refers to asymptomatic infection after the period of primary and secondary syphilis has passed.

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Secondary syphilis: Ocular syphilis manifestations including anterior or posterior uveitis.

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Secondary stage: Oral lesions called "mucous patches" resembling snail tracks.

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In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet.

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The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration) though there may be multiple sores. 

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Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum.