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There are several differences between what one used to classify as a vampire versus how they are classified now. Ultimately, there is one thing that is corresponding: illness.
There are thousands of different stories and movies in relation to vampires. Nearly half of them respond to vampires being the leading cause of illnesses such as the Tuberculosis, The Black-Plague, The Flu Pandemic, and many more.

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In 2021, Netflix fans went wild over a new TV show. Midnight Mass was extremely popular when first released. It was based on a new priest in town that brings an evil entity with him. This entity can later be identified as a vampire-like creature. Zinoman added a key scene from the show. He stated, "The violence in the show is brutal, beginning with hundreds of dead cats washing up on the beach, assumed to be the result of illness."

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A famous book series, Twilight: The Twilight Saga written by Stephenie Meyer, is based around a family of vampires and an angsty teen searching for love. This is a great example of how vampires have evolved throughout time. Stephenie Meyer does a great job catching her reader's attention by making you fall in love with the characters. What was once portrayed to be evil, has been proven otherwise. "Bloodsuckers were no longer monstrous others. Now they were romantic outsiders and even heros fighting their own natures for the love of others." (3)

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In 1954 Richard Mathenson's published a book titled, " I Am Legend" In this novel, it is based on the last man on Earth after a world-wide plague completely wipes out all most of humanity. With the twist of replacing some of the remaining life, with vampires. The cause of this was not immunizations more or less due to an attempt to cure cancer.

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During this century, vampires had become exceptionally sexualized. There were still books and movies that traced vampires and deadly diseases together but, during this time the main focus was romanticism.

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In 1920 as the Flu Pandemic came to an end, the German expressionist classic known as "Nosferatu" was created. Zinoman included, "With his rodent-like teeth, elongated fingers and skeletal silhouette, the terrifying vampire not only looks like a rat, widely known as the deliver of the Black Plauge" (3)
Relating back to the 11th and 12th-century vampires, Nosferatu has been compared to a deadly virus.

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In 1897, Bram Stoker had written a novel about a nobleman from Transylvania who had left his castle to travel to London in the hopes of finding fresh blood.
Zinoman stated, "Along with giving Dracula the ability to shape-shift into a bat, he expanded the range of anxieties associated with the vampire, turning it form a symbol of sickness into one of repressed desire." (3)
This has provided the readers to understand the beginning stages of the evolution of vampires.

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During the 19th century, there was an emergent fixation on vaccinations. This ordeal had been a touchy subject and received mass amounts of backlash. Zinoman included, "The first compulsory vaccination laws were enacted in England, sparking a backlash movement that used the vampire as a metaphor for bodily violation, with fangs representing surgical instruments." (2) Nadja Durbach, a historian and author of the book Bodily Matters: The Anti-Vaccination Movement in England, 1853-1907, insisted that the anti-vaccination movement was an important context for Dracula.

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Throughout time between the 11th century and the 19th century, Vampires went through a transitional phase in pop culture. They went from being associated with disease in the 11th-and 12th-century to being characterized as "wealthy creeps in formal wear" in the 19th-century.

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Starting in the early 11th-and 12th- century, when the outbreak of Tuberculosis had happened, Vampires were partially to blame. According to Zinoman, "Rooted in folklore, they were symbols of epidemics..." (1)