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Induced fit hypothesis is a model ... it’s  when the shape of the enzyme’s active site is not complementary to the substrate binding to it... in this process the active site will change shape to become complementary to a specific substrate forming an enzyme substrate complex ... when the product is formed the active site will return back to its original shape

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kyrillos Induced fit model

Description:

induced-fit hypothysis, states that the binding of a substrate or some other molecule to an enzyme causes a change in the shape of the enzyme so as to enhance or inhibit its activity.

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The induced fit hypothesis states that the shape of active sites are not exactly complementary but changes shape in the presence of a specific substrate to become complementary. When a substrate molecule collide with an enzyme, if its composition is specifically correct, the shape of the enzyme’s active site will change so that the substrate fits into it and an enzyme substrate complex can from. The reaction is catalyzed and an enzyme product complex forms. the shape changes back to normal once the product leaves.

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its the idea that the substrate fitting into the active site is not enough for the enzyme to catalyze the reaction. along with that the enzymes active site shape is changed in order for the reaction to occur . the substrate and enzyme are not 100percent complementary

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Induced fit hypothesis is a modification of the key and lock hypothesis. When an enzyme and substrate combine, the enzyme's active site is flexible so it changes its shape to become complementary to the part of the substrate so it could be attached. The amino acids in the enzyme control the flexibility of the active site.

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it is considered to be the enzyme in which the substrate will fit into

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it is considered to be the substrate in which it fits into its complimentary shape in the enzyme's active sit

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leen musleh
the binding of the substrate induces the active site to slightly change its shape to perfectly fir around the substrate and hug it tightly.
it is reshaped by interactions with the substrate.
the amino acids of the the active site are molded

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Lock and Key hypothesis
— Leena Mazin
Emil Fischer proposed this hypothesis that refers to the specificity of the enzyme.
Similar to a key into a lock, only the correct size and shape of the substrate would fit into the active site of an enzyme

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it is a hypothesis in which the lock and key model are considered to display how an enzymatic reaction forms from a key(substrate) fitting into its specific complimentary shaped active site in a lock (enzyme)  forming temporary bonds between R groups of amino acid and substrate in active site.

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In the lock and key hypothesis the lock represents the enzyme whereas the key is used to represent the substrate, in which only the correctly shaped and sized key {substrate) fits into  the key hole (active site) of the Lock {enzyme}.
When binding takes place neither the shape of the enzyme {Lock] nor the shape of the substrate {Key} actually change.

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Lock and key

The lock and key hypothesis states that the substrate fits perfectly into the enzyme, like a lock and a key would, so theyre shapes are complimentary together and the substrate is specific to the enzyme(unlike induced lock and key, the enzyme and the substrate dont need to change their shape)

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states that the substrate fits perfectly into the enzyme, like a lock and a key would.

It also states that both substrate and enzyme will deform a little to succefully bind to each other

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this specific tertiary shape is very important  for the function of the enzyme. The active is there the substrate react with the enzyme forming a a key-lock complex. The shape of the active site differs from one enzyme to another due to different folding of amino acid chains.The enzyme reacts with a specific substrate, which fits the active site

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energy required to start chemical reaction.
Enzymes lower this activation energy and in turn speed up the chemical reaction. this increases the rate of the reaction. The specific action of an enzyme with a single substrate can be explained using a Lock and Key. the shape of the active site matches the shape of its substrate molecules. This makes enzymes highly specific. Each type of enzyme can usually catalyze only one type of reaction (some may catalyze a few types of reactions). Temporary bonds are formed b/n enzyme and substrate

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In the lock and key hypothesis, the substrate must be of a complementary shape so it can fit into the specific shape of the active site. The substrate diffuses into the active site and binds to it. The substrate form temporary bonds with the amino acids in the enzyme to produce an enzyme-substrate complex. A reaction takes place where the temporary bonds are broken down. The enzyme-substrate complex (large molecule) will be broken down into an enzyme-product complex (smaller molecules). The products unbind from the active site and diffuse out. The enzyme can be used again

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energy required to start a reaction . the higher the Ea the slower the chemical reaction will be
measured in joules per mole
it is needed so reactants can move together  and overcome forces
you must add activation energy to initially break the chemical bonds. Catalysts simply lower the activation energy needed to do the chemical reaction going. reactions to occur without themselves being used up in the reaction. Energy is usually needed to break the bonds and get the reaction going.Energy is produced when these bonds are formed. The difference between these two energies is the enthalpy change. The energy required to break the bonds and start the reaction is called the Activation energy

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mena saher
Activation energy: is the energy required for a reaction to occur and it determines its rate.
The higher the Activation energy, the slower the chemical reaction will be.
Enzymes lower the Activation energy, when an enzyme binds to it's substrate, it'll lower the Activation energy of the reaction. Allowing it to happen and occur faster.
An enzyme is a catalyst, it increases the rate of reaction by lowering the Activation energy while not being used up or consumed in the process.
Example of reaction: lactase produces lactose breaking it into smaller parts.
Example of enzymes: 1) lipase giving lipids, 2)protease giving proteins, 3) amylase giving starch.
Enzyme substrate complex can also lower the Activation energy by bending substrate molecules in a way that smoothes bond breaking helping it to reach transition state.
Transition state is when the substrate is no longer a substrate but a product.

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Activation energy is defined as the minimum amount of extra energy required by a reacting molecule to get converted into product. It can also be described as the minimum amount of energy needed to activate or energize molecules or atoms so that they can undergo a chemical reaction or transformation.

Factors Affecting Activation Energy
1. Nature of Reactants
2. Effect of Catalyst
Positive catalyst provides such an alternate path in which the value of Ea will be low, while the negative catalyst provides such an alternate path in which the value of Ea will be high.

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Chemical rxn require a certain amount of energy, it is needed to break the bonds of the reactants this is called activation energy..in the body the energy req is usually in form of heat, the reactants absorb this energy until it becomes unstable and it s bonds broke (also due to vibration and collision)... enzymes lowers this amount of energy, so the reaction will be quicker and at lower temp (speeding up rxn)

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activation energy is the minimum amount of energy needed to start the reaction. enzymes lower the energy needed by forming temporary bonds and modifying the substrates. by lowering the activation energy they will higher the reaction rate.

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Activation energy is the energy needed for a reaction to take place , this energy is measured in Jules/Mol and can be shown using a reaction coordinate diagram. The reactant A and the product B will have different energy levels depending on the reaction , whether its exo thermic or endo thermic . Enzymes are used to reduce the activation energy needed and thus reduce the reeaction time

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Rawdah: I liked what you did Rawdah..Bravo

Activation energy is the minimum amount of energy that reactants must possess in order for a chemical reaction to start. Enzymes lower the activation energy speeding up th  chemical reaction without being used up themselves.

Enzymes dont affect the energy absorbed or released but affect the 'transition state'