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ANS, Part 1 Power Point: Document name found in blackboard "1-DL ANS, Part 1.pptx"
This is what I used as a resource for my entire padlet homework!

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"rest & digest"
cholinergic

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Subdivision of ANS #1: Sympathetic Nervous System

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Subdivision of ANS #1: Sympathetic Nervous System

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"fight, fright, flight"
Adrenergic: stimulated with any type of stress, nervous or illness.

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Subdivision of ANS #2: Autonomic Nervous System (ANS)

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Subdivision of ANS #2: Autonomic Nervous System (ANS)

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Visceral

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ANS Neurotransmitter of Sympathetic Nervous Systems

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ANS Neurotransmitter of Sympathetic Nervous Systems

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Acetylcholine (ACH)-cholinergic neurotransmitter
Norepinephrine (NE)-adrenergic
Epinephrine (EPI)-adrenergic
Dopamine (DA)

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The receptors for each division of the ANS with main locations of each receptor listed

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The receptors for each division of the ANS with main locations of each receptor listed

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Alpha 1: found on glands, smooth muscles, eyes, most arteries & veins
Alpha 2: smooth muscle
Beta 1: located on the heart
Beta 2: located on smooth muscle, lungs, uterus, skeletal muscle arteries, coronary arteries

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Locations of where each neurotransmitter is released in each division

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Locations of where each neurotransmitter is released in each division

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Acetylcholine (ACH)-cholinergic neurotransmitter

---->@  released at ganglia from presynaptic nerve endings (both systems; end PNS & SNS)
Norepinephrine (NE)-adrenergic

---->@ released at postganglionic nerve endings
Epinephrine (EPI)-adrenergic

---->@ produced by adrenal medulla
Dopamine (DA)
----> Prescursor to NE (Norepinephrine), released @ postganglionic nerve endings

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The end organ responses that occur when stimulated.  List the specific organ and state what response is generated in that organ when stimulated by each ANS division

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The end organ responses that occur when stimulated.  List the specific organ and state what response is generated in that organ when stimulated by each ANS division

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Alpha 1: Epinephrine effect: vasoconstriction, contraction-pupillary dilation
Norepinephrine effect: vasoconstriction, contraction-pupillary dilation
Alpha 2: Epinephrine effect: decrease release of NE
Norepinephrine effect: decrease release of NE
Beta 1: Epinephrine effect: greater increase in heart rate, force of contraction,                                          &  atrioventricular conduction
Norepinephrine effect: moderate increase in heart rate, force of contraction & atrioventricular conduction
Beta 2: Epinephrine effect: bronchodilation, relaxation, vasodilation
Norepinephrine effect: norepinephrine does not stimulate beta-2 receptors

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The drug classifications for each division of the ANS. Under each drug classification, identify which receptors are interacted with and include the action that occurs.

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The drug classifications for each division of the ANS. Under each drug classification, identify which receptors are interacted with and include the action that occurs.

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Alpha-1 Adrenergic Agonists
alpha-1 receptor is stimulated
contraction of smooth muscle, blood vessels constrict, increases BP , vasoconstriction of nasal passages à decongestant effect

Adrenergic Agonists
This category works by Stimulates all alpha and beta receptors, an exception *AN EXCEPTION BECAUSE IT STIMULATES ALL*

Vasopressor-vasoconstriction, increases BP, Cardiac stimulant, Bronchodilator

Alpha-1 Adrenergic Blocking Drugs

binds to alpha-1 receptors and blocks them

relaxation of smooth muscle, vasodilation of blood vessels, decreases BP, relaxes smooth muscle of ureters and increases urine flow

Beta Adrenergic Agonists
Beta -1 Adrenergic Agonists
Low dose-stimulates dopaminergic (d-1) receptors in kidneys causing vasodilation and increased renal blood flow

Moderate dose-stimulates  beta 1 receptors-heart, increases force of contraction and cardiac output

High dose- stimulates alpha-1 receptors causing vasoconstriction à increase in blood pressure

Beta Adrenergic Agonists
Beta-2 Adrenergic Agonists
stimulates beta 2 receptors, relaxation of the smooth muscle of the lungs à bronchodilation, relaxation of the smooth muscle of the uterus

Beta-Adrenergic Blocking Drugs
Selective Beta-1 Blockers
beta-1 receptor is blocked (antagonizes beta-1 effects of NE and EPI)  , decreases force of contraction  (negative inotropic), decreases cardiac output, decreases HR  (negative chronotropic) , decreases conduction (negative dromotropic), decrease in cardiac output also decreases BP

Beta-Adrenergic Blocking Drugs
Non-selective Beta Blockers
block beta-1 and beta-2 receptors , decreases force of contraction  (negative inotropic), decreases cardiac output, decreases HR  (negative chronotropic) , decreases conduction (negative dromotropic), decrease in cardiac output also decreases BP, can cause bronchoconstriction

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List specific drug examples found on the Unit 2 drug list under each drug classification;  include the generic (lowercase) and brand (capitalized in parentheses with the trademark symbol at the end- ®)

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List specific drug examples found on the Unit 2 drug list under each drug classification;  include the generic (lowercase) and brand (capitalized in parentheses with the trademark symbol at the end- ®)

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Alpha-1 Adrenergic Agonists
Drugs:

1. ephedrine-increases BP

2. phenylephrine (Neo-Synephrine®)- increases BP, nasal decongestant

Adrenergic Agonists
(mimic sympathetic system)
Drugs:

1. epinephrine (Adrenalin®)

Alpha-1 Adrenergic Blocking Drugs
(Block adrenergic or sympathetic system @ the Alpha 1’s)
Drugs:

1. prazosin (Minipress®)-HTN

2. terazosin (Hytrin®) -HTN, BPH

3. doxazosin (Cardura®)-HTN, BPH

Beta-1 Adrenergic Agonists
Drugs:

1. dobutamine

Beta-2 Adrenergic Agonists
Drugs:

1. albuterol (Proventil®, Ventolin®)-bronchodilator

2. terbutaline (Brethine®)-bronchodilator, uterine relaxant

3. formoterol (Foradil®)-bronchodilator

4. salmeterol (Serevent®)-bronchodilator **LONG ACTING**

Beta-Adrenergic Blocking Drugs- Selective Beta-1 Blockers
Drugs:

1. atenolol (Tenormin®)

2. metoprolol (Lopressor®)

**Beta-1 generic drugs end in –olol**

Non-selective Beta Blockers -Beta-Adrenergic Blocking Drugs
Drugs:

1. nadolol (Corgard®)

2. propanolol(Inderal®)

3. timolol (Blocadren®)