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Two Divisions of ANS & alternate names.

Sympathetic

- Adrenergic= when the body responds to stress or illness with the system
(Fight, Fright, Flight)

Parasympathetic

- Cholinergic= Active during the times when  you rest and digest.

(Rest, Diegest)

Other names

the sympathetic nervous system, the parasympathetic nervous system and the enteric nervous system.

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Neurotransmitter for sympathetic

Norepinephrine (NE)-adrenergic

Epinephrine (EPI)-adrenergic

- made in the adrenal medulla then is synthesized from dopamine and then released as a hormone into the blood. Epinephrine is made from norepinephrine inside the adrenal medulla

https://www.medicalnewstoday.com/articles/325485#:~:text=The%20adrenal%20medulla%2C%20the%20inner,such%20as%20low%20blood%20pressure.

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receptors with main locations

Sympathetic

- alpha 1: located on the glands, smooth muscle, eye most arteries and veins
- alpha 2: relaxes inhibits. parasympathetic response
- beta 1: located o n  the heart
- beta 2: located on the lungs smooth muscles uterus skeletal muscles arteries coronary arteries

Parasympathetic

- muscarinic: located on cardiac, smooth muscle, and glands
- nicotinic 1: located in synapse area
- nicotinic 2 : somatic, neuromuscular junction of skeletal muscle

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neurotransmitters for parasympathetic

Acetylcholine

- stored in vesicles at the ends of cholinergic neurons. In the peripheral nervous system, a nerve impulse arrives at the end of a motor neuron. Acetylcholine is then released into the neuromuscular junction.

https://www.britannica.com/science/acetylcholine

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Organ Responses: Sympathetic

Arteries=  Vasoconstriction

Heart =Increases rate

GI motility and secretions =Decreased

Pupil of the eye= Dilation (mydriasis)

Respiratory passages, lower= Bronchodilation

Urinary Bladder Wall=  Relaxation

Urinary sphincter = Contraction

Uterus (pregnant) body= Relaxation

|Uterus (pregnant) outlet= Contraction

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Organ Response: Parasympathetic

Arteries = none

Heart= decrease

GI motility and secretions= increased

Pupil of the eye= Constriction (miosis

Respiratory passages, lower= Bronchoconstriction

Urinary Bladder Wall=Contraction

Urinary sphincter=Relaxation

Uterus (pregnant) body= none

Uterus (pregnant) outlet= none

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Drug classifications: sympathetic

Arteries= Vasoconstriction (alpha 1) Vasodilation, Coronary arteries (beta 2) ·

Arteries of skeletal m. (beta 2) ·
Cerebral arteries

Heart= Increases rate (beta 1)

GI motility and secretions= Decreased (alpha 1)

Pupil of the eye= Dilation (mydriasis)  (alpha 1) Respiratory passages, lower= Bronchodilation (beta 2)

Urinary Bladder Wall= Relaxation (beta 2)

Urinary sphincter= Contraction (alpha 1)

Uterus (pregnant) body= Relaxation (beta 2)

Uterus (pregnant) outlet= Contraction (alpha 1)

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Drug classification: parasympathetic

Arteries= None

Heart= Decreases rate (muscarinic)

GI motility and secretions= Increased (muscarinic)

Pupil of the eye= Constriction (miosis)   (muscarinic)

Respiratory passages, lower=  | Bronchoconstriction (muscarinic)

Urinary Bladder Wall= Contraction (muscarinic)

Urinary sphincter= Relaxation (muscarinic)

Uterus (pregnant) body= none

Uterus (pregnant) outlet= none

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Sympathathetic

Alpha-1 Adrenergic Agonists

ephedrine, phenylephrine (Neo-Synephrine®)
Adrenergic Agonists
epinephrine (Adrenalin®)
Alpha-1 Adrenergic Blocker

prazosin (Minipress®)

terazosin (Hytrin®)

doxazosin (Cardura®)
Beta-1 Adrenergic Agonist

dobutamine
Beta-2 Adrenergic Agonist
formoterol (Foradil®)
albuterol (Proventil ®/Ventolin®)

terbutaline (Brethine®)

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Parasympathetic

Direct Acting Cholinergic Agonist

acetylcholine

pilocarpine (Pilocar®)

bethanechol (Urecholine®)

Indirect Acting Cholinergic Agents

neostigmine (Prostigmin®)