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Global disease burden assesses health loss from disease globally, mortality being a measure of assessment included. As ischemic heart disease is a significant disease contributor, assessing mortality from IHD is a useful tool for approaching interventions and prevention of IHD.

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Risk factors contribute to disease burden and help inform approaches to reducing burden in populations.

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This article illustrates the global burden of disease of CVD in People Living with HIV. The intersection of CVD and HIV serves as an excellent model for the global burden of disease, as they are both major contributors to global disease burden. This article finds that people living with HIV are twice as likely to develop cardiovascular disease, serving as a risk factor for CVD and thus compounding the global disease burden.

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This illustration demonstrates the disparities in causes of death, in which CVD is not as significant as cancer in high-income countries, thus indicating that disease burden has a different meaning across different locations and populations.

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Cardiovascular Disease: World's #1 Killer

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Cardiovascular Disease: World's #1 Killer

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This infographic illustrates the various impacts cardiovascular disease has on health globally, including risk factors. It also shows CVD's rates of death compared to other causes of death, illustrating its significant cause in the global burden of disease.

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The global burden of disease concept allows for public health and global health advocates to conceptualize and quantify health loss in a standardized manner in order to assess the health needs of various populations and how to improve health outcomes.   By utilizing data and creating a method of analysis of illness, injury, and death, global health advocates are able to understand, develop, and evaluate interventions and prevention plans to improve health for all. Diseases such as ischemic heart disease and cardiovascular disease are effective models for understanding the global burden of disease due to their significant contributions to causes for global burden of disease.