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-How does his red blood cells hold oxygen?
-How does the hemoglobin's shape matter?

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What do the red and purple spots in the hemoglobin of a healthy person and the patient represent? How essential is the red spots to the function of the hemoglobin?

How important is it for hemoglobin to be clustered together and not scattered as shown in Shawn? Why?

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1: How long does Shawns symptoms last?

2: Is there a treatment for this disorder?

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is this symptom an everlasting one and won’t go away?

Does this symptom lead to any other symptoms?

Can this symptom be detected right after birth or are they hidden?

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What does the different shapes of both his hemoglobin and blood cells have to do with his symptoms?

how are his symptoms related to these different structures?

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is the hemoglobin structure a genetic defect or a cause and effect relationship as it the person did something bad that made the structure this way?
is there a way to help or even cure this condition?

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1.Does the patient's family have a similar shape in red blood cells?

2.Does the abnormality of the structure change with movements? and/or changes within the bodies homeostasis?

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- Can there be any treatments to this disorientated blood cells/Hemoglobin.
- Can environmental factors contribute to the the shape of abnormal red blood cells/Hemoglobin.

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How will the loose structure of the hemoglobin affect the body systems and functions?

What causes the red blood cells to deform and turn into a skinny structure?

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1) How does the shape of blood cells affect the transport of oxygen?
2) Are there other factors to his fatigue and shortage of oxygen?

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1. If shawn’s hemoglobin is scattered, is there a treatment that would allow him to be have a normal hemoglobin again?

2. If shawn’s red blood cells are thin and crescent shapes,  is that what causes his fatigue as well?

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1. Does the crescent-shape of Shawn’s red blood cells hinder the transportation of oxygen throughout his body
2. Does the abnormal shape of Shawn’s hemoglobin cause fatigue because of reduced cellular respiration?
3. What is the purpose of the entangled, complex structure of the hemoglobin?

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1. Why does the hemoglobin of the patient contained the color of pink, yellow, blue, and green. While a normal hemoglobin contained the color of red, yellow, blue, and green.
2. How does the sickle cells contribute to the problem of Hemoglobin abnormality.

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-Does the disorder affect the production of the red blood cells or the cells itself?

-Does this have an affect on the other cells in his body

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1. Is the scattered hemoglobin what causes Shawn’s red blood cells to be a crescent-shape?

2. What is the role of the red spots in the hemoglobin?

3. Do the red spots turn purple when the hemoglobin scattered?

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-What causes Shawn’s Hemoglobin to be a different color?
-How does Shawn’s Hemoglobin affect red blood cell production?

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Why does his sample of hb have small samples of pink?

-How does the sample of hb connect to his situation?

How does the shape of the hb affect the blood cells?

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How does not having the red structure in the hemoglobin affect the whole hemoglobin?

When do the blood cells start to deform into these “sickles”?

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-Does the condition have any other side effects?

-Why is it only present in certain people in Shawn’s family?

-How does the Hemoglobin impact the structure of blood cells?

-How does his body react to intensive exercise?

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How can the structure of the Hb affect a blood cell?

What went wrong in his red blood cells that caused it to be so thin?

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What causes Shawn’s blood cell disorder?
How does the shape of his hemoglobin affect the overall efficiency of transporting oxygen within his body?

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- Does Shawn’s body produce more red blood cells to make up for the inefficiency of his crescent shaped red blood cells?

- Does his crescent shaped red blood cells cause there to be more CO2 in his body.

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-Does sickle cell get worse over time?
-Does Shawn produce more blood cells to make up for his small ones?

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1) What does Shawn do to trigger these attacks? Does he do some strenuous exercise?
2) How does he get rid of the symptoms?
3) How often does he get an attack?

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Does the lack of oxygen cause Shawn's body pain?
Is the pinkish thing in the patient's hb causing the symptons.

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-How did the patient's hemoglobin become open and structured like it was torn apart?

-Does the patient’s red blood cells have the same amount of hemoglobin proteins as a normal person’s hemoglobin in each red blood cell?

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What cause the Hb to become loose?

What is the purple-ish thing in patient Hb?

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-Does the loose hemoglobin structure have a direct connection with the thickness of the red blood cell, or just the ability to transport oxygen?

-Does the HB abnormality affect the transport of carbon dioxide as well?

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Why does a difference in the shape of red blood cells cause a lack of oxygen?
How does hemoglobin contribute to the overall efficiency of the red blood cell being able to transport oxygen?
Have Shawn’s symptoms worsened over the years or are they the same as when he first experienced it?

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Can the abnormal Hemoglobin structure in Shawn’s body be altered to have the normal structure?

What causes the changes in Hemoglobin structures?

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What role does Hemoglobin play in the structure of red blood cells

Is there any treatment to this disorder or way to nullify it

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Directions:  Go to the plus sign in the lower right corner to add your questions to our Wonder Wall.

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Directions:  Go to the plus sign in the lower right corner to add your questions to our Wonder Wall.

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Wonder:  Scientific questions lead to explanations of how the natural world works and can be tested using evidence.  Scientists ask questions to develop or refine an explanation about the natural world.  What scientific questions do you have about what you have observed so far?