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The study “Semantic Memory Functional MRI and Cognitive Function After Exercise Intervention in Mild Cognitive Impairment” (Journal of Alzheimer’s Disease) was performed to see if exercise would increase memory retrieval in older adults with mild cognitive impairment (associated with early memory loss).

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Semantic Memory fMRI and Cognitive Function After Exercise Intervention in Mild Cognitive Impairment

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Mild cognitive impairment (MCI) is associated with early memory loss, Alzheimer neuropathology, inefficient or ineffective neural processing, and increased risk for Alzheimer’s disease (AD). Unfortunately, treatments aimed at improving clinical ...

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The article “Effects of Bracing in Adolescents with Idiopathic Scoliosis” (New England Journal of Medicine) reports on the role of bracing patients with adolescent idiopathic scoliosis (curvature of the spine) for prevention of back surgery.

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1-800-843-6356 | [email protected]

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In The New England Journal of Medicine, the article “Increased Survival in Pancreatic Cancer with nab-Paclitaxel Plus Gemcitabine” reports on an experiment to test which treatment, nab-paclitaxel plus gemcitabine or gemcitabine alone, is the most effective in treating advanced pancreatic cancer.

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Doctors conducted a randomized trial of hypothermia in infants with a gestational age of at least 36 weeks who were admitted to the hospital at or before six hours of age with either severe acidosis or perinatal complications and resuscitation at birth and who had moderate or severe encephalopathy.  The trial “Whole-Body Hypothermia for Neonates with Hypoxic–Ischemic Encephalopathy” tested two treatments, standard care and whole-body cooling, for 72 hours.

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“Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer (WHS)“

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“Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer (WHS)“

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https://www.clinicaltrials.gov/ct2/show/results/NCT00000479?recrs=e&rslt=With&age=01&draw=3&rank=44561

- random assignment
- 39,876 participants is a sufficient amount
- there was a control group
- groups: 1) vitamin E and aspirin 2) vitamin E and placebo 3) aspirin and placebo 4) placebo and placebo
- doesn’t really show a super clear cause and effect relationship

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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.

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Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer - Study Results - ClinicalTrials.gov

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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.

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Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection

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Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection

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a) The efficacy & safety of orally administered tebipenem pivoxil hydrobromide as compared with intravenous entrapenem in patients with complicated urinary tract infection or acute pyelonphritis.
b) Patients were randomly assigned to a 1:1 ratio to recieve oral tebipenem pivoxil hydrobromide or intravenous ertapenem.
c) Yes, group 1 with tebipenem pivoxil hydrobromide, group 2 with intravenous ertapenem.
d) Yes, 1372 hospitalized adult patients.
e) No, oral tebipenem pivoxil hydrobromide was noninferior to intravous ertapenem in treatment of complicated urinary tract infection or acute pyelonphritis.

-Lucy Grote

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108408/