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It is a type of disorder that affect the nerve cells that control voluntary muscle movements such as walking and talking. This causes the motor neuron to deteriorate and later on die.

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The type of effect that happens to you when you get ALS is you start to lose control of moving your body this is because the motor neuron is deteriorating and dying.

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You lose almost all control of your body and start dying because your lung muscles don't work so you are not getting oxygen, this leads to death which is the final stage of ALS.

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It affect as many as 30000 people, this could have been bigger but the people who had ALS just dies. For every year 5000 more people get ALS.

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It say to kill 5 people for every 100000 death at the age of 20 or older. ALS is the most common at people who are 60 and above.

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ALS gets inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations.

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Electromyogram (EMG).

Nerve conduction study.

MRI.

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Can they be directly test and can you use amniotic fluid?

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Can they be directly test and can you use amniotic fluid?

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No they can not check directly usually they review the tests before giving a diagnosis and they can't use amniotic fluid because ALS does nothing to amniotic fluid.

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There are two type of therapies and both are drug. Riluzole which is a drug that can increase life expectancy to 3 to 6 months. Edaravone another type of drug allow the person with ALS to reduce the decline in daily functioning.

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ALS was discovered in 1869 by French neurologist Jean-Martin Charcot. It started to get more attention internationally in 1939 after killing a famous baseball player his name was Lou Gehrig.

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ALS Association is a support organization that makes no profit and helps people who have ALS. A nearby chapter is the Orange County Chapter which supports people with ALS.

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A celebrity that is promoting ALS is a baseball player. This helps show that ALS is a problem and this allows more people to know about it. Sadly this baseball player had ALS and sadly died later on but it shows what the people needed to do with ALS. The baseball player's name was San Francisco 49ers player Dwight Clark.

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The Walk to Defeat ALS is a day where people raise money for ALS. The day that it happens is different for each state so I only say our Walk to Defeat ALS day which is May 14, 2022.

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The gene that causes ALS is when C9orf72 starts mutations, this affects 30% to 40% of ALS people. Another gene is SOD1. This affects 15% to 20% of ALS people. The last genes only affect 5% of ALS people which are TARDBP and FUS.

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Stephen Hawking, he had ALS for 55 years which is the longest time to live with ALS. He died at the age of 76 in 2018.

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It is 100% fatal so there are no chances of survival and there is no cure for ALS.

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By average the life expectancy is 2 to 5 years. So to compare to the longest living person he live with ALS for 55 years.

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Diagnosis is very hard to do because in order to diagnose someone you have to rule out all the other diseases first before you can say they have ALS.

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Mayo Clinic
Link:Amyotrophic lateral sclerosis (ALS) - Symptoms and causes - Mayo Clinic

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MedlinePlus
Link:Look at the Causes, place them at the bottom of the page

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Mayo Clinic
Link:Amyotrophic lateral sclerosis (ALS) - Symptoms and causes

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Johns Hopkins Medicine
Link: ALS, Amyotrophic Lateral Sclerosis, Lou Gehrig's disease

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MedlinePlus
Link:Amyotrophic lateral sclerosis: MedlinePlus Genetics

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Mayo Clinic and the ALS Association
Link:Amyotrophic lateral sclerosis (ALS) - Diagnosis and treatment - Mayo Clinic

Genetics Testing - The ALS Association

Genetic Testing for ALS | The ALS Association

Obtaining an ALS Diagnosis | The ALS Association

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Mayo Clinic and BioPharma Dive
Link:Amyotrophic lateral sclerosis (ALS) - Diagnosis and treatment - Mayo Clinic

On the hunt for new ALS drugs, researchers see progress, and a long road ahead | BioPharma Dive.

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The ALS Association and National Institute of Neurological Disorders and Stroke
Link:Helping You Understand ALS | The ALS Association. Amyotrophic Lateral Sclerosis (ALS) Fact Sheet | National Institute of Neurological Disorders and Stroke

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CDC and ALS Association
Link: Organizations that Support ALS Patients and Caregivers

http://weboc.alsa.org/site/PageServer?pagename=OC_homepage&_ga=2.59620901.969902862.1651506620-1924520794.1651506620

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Alstreatment
Link:Famous People Who Have or Have Had ALS - Alstreatment.com

Chapter Highlights

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Wikipedia and VA Health Care
Link:https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwjRg7v79sj3AhUYC0QIHSqOCgcQFnoECAkQAw&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FList_of_people_with_motor_neuron_disease&usg=AOvVaw2bO8ZdmbMKW4jY_WTjxNT3

sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwiQxqu198j3AhWFIUQIHelXANoQFnoECAYQAQ&url=https%3A%2F%2Fwww.research.va.gov%2Fprograms%2Ftissue_banking%2Fals_caregivers%2FALSFactSheet_NAR.pdf&usg=AOvVaw1ZfxeB39WCj3RQgk4wuoZF