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GB happens post infection, especially with COVID and Zika

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Antibodies against the myelin sheath in PNS.

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Targets myelin sheath in the periphery. We have M1 and M2. M1 are pro-inflam and M2 is anti-inflam. TNF is M1 and TGF is M2

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GB: induced by virus.

Antibodies to myelin

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It will result in performance of the microglia that releases cytokines IFN-gamma and IL-Ibeta

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acute response immediately M1 - pro inflammatory

later response M2 - Anti inflammatory.

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caused by viruses targeting the myelin. No action potentials problems with muscle contraction.

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IL-6, IL-1B, NO, TNF-a, IL-12, IL-23