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More severe infections occur in people who are already hospitalized with another illness or condition, or people who have a weak immune system. Infections can occur in any part of the body. Symptoms depend on which part of the body is infected. Antibiotics are used to treat the infections. Pseudomonas infection could be fatal in people who are already very ill. Pseudomonas aeruginosa causes urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections and a variety of systemic infections, particularly in patients with severe burns and in cancer and AIDS patients who are immunosuppressed. Symptoms include: Chills, fever, fatigue, redness of skin. Thoroughly washing hands and cleaning equipment in hospitals can help prevent infection. Outside a hospital, avoiding hot tubs and swimming pools that are poorly cared for can help prevent infections.

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Pseudomonas aeruginosa is a Gram-negative pathogen that causes severe acute and chronic infections at different sites within the body such as urinary tract, skin (burn or surgical wounds), and the respiratory tract.