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http://ghr.nlm.nih.gov/dynamicImages/chromomap/TFR2.jpeg

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- Iron overload disease
- Overload of iron
-Extra iron in your body can lead to damage organ such as liver, heart and pancreas

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- If two carrier have a child then there is 50% chance of the children will be carrier and 25% of the children being normal and 25% the children having both defected HFE gene
- Serum transferrin saturation measures the amount of iron bound to protein that carries iron in your blood system.
- Serum ferritin measure the amount of iron stored in liver.

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http://www.hemochromatosisdna.com/media/images/hemochromatosis-symptoms.jpg

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- The person can live their normal life if they are treated before the organ are damaged.
- If the person is treated before the Serum Ferritin is less than 1,000ng/ml the risk of liver cancer is less than 1%

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-Therapeutic blood removal
- Regular blood donation
- After the person gets back to normal, the person need to donate blood every 2 or 4 month for life

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- HFE gene provides instruction to produce protein.
- Molecular location on Chromosome 6: base pairs 26,687,281 to 26,096,117

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-Diabetes
- Heart failure
- Liver failure

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-Joint pain
-Abdominal pain
-Fatigue
-Weakness

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how you would advise prospective parents on the disorder

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how you would advise prospective parents on the disorder

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Theres ferritin tests that can be done to determine how much blood needs to be removed. They have to do blood donations, eating better, and they can go to therapy

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http://www.epainassist.com/images/Hemochromatosis.jpg

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-Type 1 is one of the most common genetic disorders in the united states.
-About 1 million people are affected.
- usually affects people of northern European decent . -The other three types are considered rare.

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-types q,2, and 3 are in an autosomal recessive pattern meaning that both of the genes have a mutation. The parents carry the copy but they don't show any signs.

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-types 1, 2, and 3 are autosomal recessive where type 4 is autosomal dominant
-x linked recessive

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"Hemochromatosis." Britannica School.Encyclopædia Britannica, Inc., 2016. Web. 24 Feb. 2016
"Hereditary Hemochromatosis." Genetics Home Reference. N.p., May 2015. Web. 26 Feb. 2016.
"Hemochromatosis." Symptoms and Causes. N.p., 22 Dec. 2015. Web. 25 Feb. 2016.
"HFE Gene." Genetics Home Reference. N.p., n.d. Web. 25 Feb. 2016.
"Treatment." Hemochromatosis.org. N.p., n.d. Web. 26 Feb. 2016.
"Hemochromatosis." Diagnosis. N.p., 22 Dec. 2015. Web. 29 Feb. 2016.