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This video helps visualize the hereditary aspects of gene expressions in breast cancer patients and how the mutant gene is expressed in offspring.

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Hereditary Testing - By BioTechnologies MD, Inc.

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Reasons to choose BioTech for your hereditary testing: 1 - We provide simple, clear and easy medical reports; 2 - We offer customization of care by offering geneticist advising before and after the genetic analysis; 3 - Our results and reports are given quickly; 4 - We cover analysis of more genes associated with the diseases, increasing the accuracy of the diagnosis and treatment; 5 - Our analysis are more affordable when compared to conventional techniques; 6 - Streamlined health insurance reimbursement process; 7 - We provide an easy and fast method for collection and remittance of samples.

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Visualization of SNPs in the genome.

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SNPs (Single Nucleotide Polymorphism)0 (Better Explained)

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This video should help understand the process of Polymerase Chain Reactions in creating billions of DNA amplifications. This automated process bypasses the need to use bacteria for amplifying DNA.

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This video helps list some ways DNA Technology can work to diagnose and treat diseases.

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integrated dna technologies (business operation)

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Applications of DNA technologies | Biomolecules | MCAT | Khan Academy

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Visit us (http://www.khanacademy.org/science/healthcare-and-medicine) for health and medicine content or (http://www.khanacademy.org/test-prep/mcat) for MCAT related content. These videos do not provide medical advice and are for informational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment.

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A genetic profile is currently taken to mean a set of genetic markers such as SNPs. In the future, however, it will likely mean the complete DNA sequence of an individual (once sequencing becomes inexpensive enough). The ability to sequence a person's genome rapidly and inexpensively is advancing faster than the development of appropriate treatments for the conditions we are characterizing. Still, the identification of genes involved in these conditions provides us with good targets for therapeutic interventions.

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Many doctors and researchers envision a future of "personalized medicine" where each person's genetic profile can inform them about diseases or conditions for which they are especially at risk and help them make treatment choices.

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Various medical techniques have prompted the improvements in disease treatments. For example, by analyzing the expression of genes in breast cancer patients, researchers have been able to refine their understanding of the different subtypes of breast cancer. Knowing the expression levels of particular genes can help physicians determine the likelihood that the cancer will recur, thus helping them design an appropriate treatment. Given that some low-risk patients have a 96% survival rate over a ten-year period with no treatment, gene expression analysis allows doctors and patients access to valuable information while considering treatment options.

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Identifying and Testing for Disease-Causing Alleles

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Identifying and Testing for Disease-Causing Alleles

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Genome-wide association studies have pinpointed single nucleotide polymorphisms (SNPs) that are linked to disease-causing alleles. Individuals can be tested by PCR and sequencing for a SNP that is correlated with the abnormal allele. The presence of particular SNPs is correlated with increased risk for conditions such as heart disease, Alzheimer's, and some types of cancer. Companies that offer individual genetic testing for risk factors such as these are looking for previously identified, linked SNPs. It may be helpful for individuals to learn about their health risks, with the understanding that such genetic tests merely reflect correlations and do not make predictions.

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Diagnosis and Treatment Diseases cont...

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Diagnosis and Treatment Diseases cont...

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Individuals afflicted with such diseases can often be identified before the onset symptoms, even before birth. PCR can also be used to identify symptomless carriers of potentially harmful recessive alles.

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Diagnosis and Treatment Diseases cont...

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Diagnosis and Treatment Diseases cont...

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Medical scientists can now diagnose hundreds of human genetic disorders by using PCR with primers that target the genes associated with these disorders. The amplified DNA product is then sequenced to reveal the presence or absence of the disease-causing mutation. Among the genes for human diseases that have been identifiied are those for sickle-cell disease, hemophilia, cystic fibrosis, Huntington's disease, and Duchenne muscular dystrophy.

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DNA technology has opened new doors for the diagnosis infectious diseases. More specifically, the use of PCR and labeled nucleic acid probes to track down pathogens. For example, because the sequence of the RNA genome of HIV is known, RT-PCR can be used to amplify, and thus detect HIV RNA in blood or tissue samples. RT-PCR is often the best way to detect an otherwise elusive infective agent.

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The practical applications of DNA-based biotechnology affect our lives in many ways

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The practical applications of DNA-based biotechnology affect our lives in many ways

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DNA technology is in the news almost everyday. Most often, the topic is a new and promising application in medicine, but this is just one of numerous fields benefiting from DNA technology and genetic engineering.

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One important use of DNA technology is the identification of human genes whose mutation plays a role in genetic diseases. These discoveries may lead to ways of diagnosing, treating, and even preventing such conditions.

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by Olivia Terrazas, Camila Risueno, and Sami Gutierrez