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Around 1600, the microscope was invented, possibly by Hans and Zacharias Jansen. Due to poor lens quality, the early compound microscopes (ones that used two lenses) could only magnify an object up to 20 or 30 times its normal size.

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1830: Joseph Jackson Lister discovers that using weak lenses together at various distances provided clear magnification.

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1903: Richard Zsigmondy invents the ultramicroscope, which allows for observation of specimens below the wavelength of light.

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1590: Two Dutch spectacle-makers and father-and-son team, Hans and Zacharias Janssen, create the first microscope

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While some older microscopes had only one lens, modern microscopes make use of multiple lenses to enlarge an image. There are two sets of lenses in both the compound microscope and the dissecting microscope (also called the stereo microscope).