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Fragile X- syndrome is an inherited condition characterized by an X chromosome that is abnormally very susceptible to damage, especially by folic acid deficiency. Affected individuals tend to be mentally handicapped and have intellectual disabilities.

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In 1943, Martin and Bell showed that a particular form of mental retardation was X-linked. In 1969, Herbert Lubs developed the chromosomal test for Fragile X. The test was not used extensively until the late 1970's. In 1991 the FMR1 gene that causes Fragile X was identified.

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Fragile X syndrome is inherited in an X-linked dominant pattern. A condition is considered X-linked if the mutated gene that causes the disorder is located on the X chromosome, one of the two sex chromosomes.

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Behavioral aggression, hyperactivity, impulsivity, nonsense word repetition, repetitive movements, self-harm, or persistent repetition of words or actions

Developmental- learning disability or speech delay in a child

Muscular- flaccid muscles or problems with coordination

Also common- large ears, speech impairment, anxiety, double jointed, enlarged head, flat feet, lazy eye, long- thin face, prominent jaw, scoliosis,, sleep disorder, sunken chest, or tremor

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Treatments for Fragile X syndrome depends on the level on severity. For the behavior aspect you can seek help through medications that will help the possible mood disorders and anxiety as well as behavior therapies. To assist their likely speech impairment you can look into speech therapists. Other medications that would lessen the other common symptoms are sedatives to keep them calm, muscle relaxant which helpes

reduces muscle tension and relieve muscle pain and discomfort, antipsychotic to

reduce or improve the symptoms of certain psychiatric conditions,cognition-enhancing medication to improve mental function, and lastly vitamins to help promote normal body function, growth, and development.

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Finding Treatments for Fragile X Syndrome -    IDDB-supported researchers are currently studying the "mGluR Theory" of Fragile X syndrome: that exaggerated signaling in mGluR (metabotropic glutamate receptor) pathways because of missing Fragile X Mental Retardation Protein (FMRP) leads to the condition's various symptoms.

Better Diagnostics and Screening Tools for Fragile X and Premutations- Several NICHD-supported research groups are seeking ways to better diagnose and screen newborns for Fragile X mutations and premutations. Early physical recognition of the characteristics of Fragile X syndrome is difficult, and new technology is being designed to detect all categories of Fragile X alleles, including full mutation expansions.
Brain Development in Fragile X Syndrome--  By the time infants with Fragile X syndrome reach 2 years old, they have a distinct pattern of brain abnormalities.A long-term study is set to discover how these patterns develop and how they are related to the signs and symptoms of Fragile X. Supported by the NICHD's IDDB, the study's researchers are examining early brain development and behavior in infants with Fragile X syndrome. The study will ultimately include 334 infants, some with Fragile X, some with ASD, and some at risk for ASD, as well as a set of control infants. The researchers will perform magnetic resonance imaging (MRI) scans at 6, 12, and 24 months of age and will collect behavioral information as well.

ECT ECT....

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If the diagnosis of the affected relative was based on previous cytogenetic testing for fragile X syndrome, at least one affected relative should have DNA testing. Prenatal testing of a fetus should be offered when the mother is a known carrier to determine whether the fetus inherited the normal or mutant FMR1 gene.

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https://fragilex.org/community/
This support system will answer any of your questions regarding Fragile X Syndrome. They also help provide quality clinics and doctors as well as helping you get involved in the Fragile X syndrome community. (contact info in link.

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http://www.friendsforfragilex.org/research/history.php
https://www.medicinenet.com/fragile_x_syndrome/article.htm
https://ghr.nlm.nih.gov/condition/fragile-x-syndrome
https://www.nichd.nih.gov/health/topics/fragilex/researchinfo/activities

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https://reachmd.com/programs/clinicians-roundtable/understanding-fragile-x-syndrome-and-related-conditions/3472/