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Zacharias Janssen invented the first model and idea of the microscope.

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Galileo Galilei developed the first compound microscope.

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Antonie van Leeuwenhoek saw the first cell using a simple microscope he built.

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The first transmission electron microscope was made by Ernst Ruska.

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In 1932 a physicist named Frits Zernike made the first ever Phase Contrast Microscope.

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In 1962, Osamu Shimomura, Frank Johnson and Yo Saiga discovered green fluorescent protein in jellyfish.

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In 1978, Thomas and Christoph Cremer developed the first practical confocal laser scanning microscope.