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Cambridge Antibody Technology group, Knoll AG and BASF Pharma test a method to replicate human antibodies

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The monoclonal antibody D2E7 (a TNFa inhibitor which targets inflammation by suppressing the physiologic response to TNF), shows positive results in clinical trials for the treatment of rheumatoid arthritis.

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Abbott Laboratories buys BASF Pharma.

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The Humira prefilled syringe enters the market. This development enables Humira patients to experience the freedom of self-administration while using a prefilled device.

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The Humira pen hits the market, which makes it easier for patients to self-administer compared to the prefilled syringe.

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Abbott split into 2 companies, one of which was AbbVie, which has current control of Humira.

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With the introduction of HUMIRA complete, patients could stay on track with treatment plans. The HUMIRA pen was also modified in 2014 to hold a two week room temperature storage capacity. This allowed patients the flexibility to take HUMIRA while away from their home.

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HUMIRA pen is redesigned to be free of citrate buffers and other enhancements. This minimizes pain immediately following injection and leads to a better injection experience.