# data[].attributes.body
Population
People with a communication deficit

Intervention
Human-machine interface-based communication system to enable communication independent of vision using just the eye-movement or the brain activity

Comparison
Eye-tracker-based communication devices

Outcome
Patients will be able to communicate independently of their vision using just their eye movement or brain activity when they are unable to move their eyes.

Time
1 month.  Within one month, the patient will be able to use the HMI-based system for communication.

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population: High-risk patients for oral cancer (tobacco users) in 3 South Asian countries i.e., India, Pakistan and Bangladesh.
Intervention: Identification and early detection of suspicious oral precancerous lesions
Comparison: Community Health Workers trained using the oral cancer screening toolkit designed by MindTech solutions vs gold standard i.e., dentists
Outcome: Sensitivity and specificity of oral cancer screening (i.e., how well can the oral cancer toolkit perform compared to the gold standard i.e., the dentists), how many referrals were created in each group, the effect of tobacco cessation advice given in each group.
Time: 1 year

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population
20 - 50 patients with a variety of deceases that effect the functions of fingers and hands.

Intervention
Our software for people with motoric deficits to control a PC.

Comparison
Closest alternative yet.

Outcome
Showing that patients who couldn't use a PC before can do it with our software.

Time
2 - 3 weeks each patient to have chance to get familiar with the way to use it as an input device.

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population
Stroke survivors with physical or cognitive impairments who have recently completed their acute rehabilitation and are currently receiving outpatient physical and speech therapy.

Intervention
Use of the Motus Health mobile app.

Comparison
Standard outpatient physical and speech therapy without the use of the Motus Health app.

Outcome
Relevant endpoints :
- Physical function
- Speech function
- Quality of life
- Adherence to prescribed therapy

Time
The clinical trial will be 12 weeks(~3 months), with assessments conducted at baseline, 6 weeks, and 12 weeks.

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population
-       Medical students;

-       Medical Schools / medical faculties of the University;

-       Medical Teachers;

-       Medical interns / Residents;

-       Hospitals / Private outpatient consultations;

-       Doctors;

-       Pharmaceutical companies.

Intervention
Simulation training platform ClinCaseQuest offer simulators of clinical cases for medical students and doctors that help to receive clinical experience in a safe patients environment and helps for reducing a years for the doctor to gain clinical experience, reducing the number of medical errors in the world and saving patients’ lives.

Comparison
need validation of the methodology

Outcome
-       To reduce a years for the doctor to gain clinical experience;

-       To reduce the number of medical errors in the world;

-       To save patients’ lives;

-       To facilitate decision-making process for doctors in real clinical practice.

Time
1 or 2 years

# data[].attributes.body
Population
Patients eligible for cancer immunotherapies

Intervention
NGS based transcriptional profiling of patients' tumor sample to create patient-specific AHR profiles

Comparison
Existing NGS tests used to determine patient eligibility for specific immunotherapies

Outcome
Patients are stratified to the correct treatment arms where they show response

Time
2 - 3 weeks (this includes time needed for acquiring the sample and performing the NGS data generation and running the prediction software).

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population
People with musculoskeletal pain
Age: 18-70
ICD M0-99
No operations/ orthetic
No neurological disease
No diabetes

Intervention
Measurement
Individuell Insoles

Comparison
Sham Insoles

Outcome
Differences in pain questionnaires (ODI = Oswestry Disability index) and Quality of life (SF-36)

Time
8 weeks duration(wearing the Insoles)
3 Measurements (M1 = pre, M2= After 4 weeks, M3= After 8 weeks)

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population: 20 - 25 people in the range of 35 and 60 years old, healthy with no articular and/or musculoskeletal pain or clinical diagnostic of related pathologies

Intervention: Use the Motiphy+ MDSW to perform a simulated physiotherapy session

Comparison: Optical motion capture system of motion capture with markers

Outcome: Validity (accuracy, precision and sensibility) of Motiphy+ results of range of motion

Time: ~2weeks. 1h introduction to Motiphy+ + 2 1h30 session with an interval of 7 - 10 days (temporal stability)

# data[].attributes.body
Population: 12-17 years old patients with anorexia or bulimia

Intervention: digital psychotherapy administrated via an app on thier smartphone

Comparison: waiting list

Outcome: weight, hospitalisation rate, symptom scale (questionnaire EDI), drop out rates, satisfaction with intervention

Time: 12 weeks for the patients, 1-2h therapy and exercises/week, assessment at beginning and end, follow-up at 6 months

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population:
- 100 Women
- pelvic pain (dysmenorrhea, dyspareunia, dyschezia) or heavy menstrual bleeding
- 15 - 50 years old

Intervention: Endometriosis diagnosis by non-expert physician using ultrasound with Xena product

Comparison: Endometriosis diagnosis by non-expert physician using only ultrasound in the same patient

Outcome: Sensitivity and specificity of diagnosis (ground truth: Ultrasound diagnosis by expert physician/ Laparoscopy)

Time: 1 hour

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time

# data[].attributes.body
Population

Intervention

Comparison

Outcome

Time