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Demirci (1)

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Frangoul (2)

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Germino-Watnick (3)

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Newby (4)

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Park (5)

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(1, 2, 3, 4, 5)

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All articles involve the mentioning of gene therapy

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All articles involve the mentioning of gene therapy

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(1, 2, 3, 4, 5)

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(2, 5)

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Half of the articles mention using different methods with results and the other half just describe the type of gene editing 

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Half of the articles mention using different methods with results and the other half just describe the type of gene editing 

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One article mentioned using CRIPSR Cas-9 gene editing for curing sickle cell anemia 

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One article mentioned using CRIPSR Cas-9 gene editing for curing sickle cell anemia 

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(3 and 5)

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The majority of the articles talk about using primary ways to cure/fix sickle cell using other gene therapies before using CRISPR since it's such a new way to gene edit genetic disorders.

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The majority of the articles talk about using primary ways to cure/fix sickle cell using other gene therapies before using CRISPR since it's such a new way to gene edit genetic disorders.

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(1, 2, 4)

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limited knowledge of the impact of SCD pathology on HSPC viability and engraftment potential

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Some articles mention using alternative therapies but touch on the topic of CRISPR

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Some articles mention using alternative therapies but touch on the topic of CRISPR

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(1, 3, 4)

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Four of the articles have used HbF induction as a form of gene therapy 

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Four of the articles have used HbF induction as a form of gene therapy 

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(1, 3, 4, 5)