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The invention of the printing press.

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King Henry the VIIIth excommunicated.

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The birth of Christopher Columbus.

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The Sistine Chapel opens.

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Publication of Martin Luther's "Theses".

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Separation of the Roman Catholic Chruch.

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Galileo Galilei discovers the principle of inertia, building the stage for a rational view of motion.

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Kepler publishes his third law of planetary motion relating the time taken for a planet to orbit the sun with its distance from the sun.

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Isaac Newton publishes one of the most important scientific books ever: Philosophiae Naturalis Principia Mathematica, revolutionizing physics and our understanding of gravity and motion.

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The study of Biology and birth was in a major process during that time.

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The Declaration of Independence was signed.

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The French Revolution started and ended in 1974.

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Here's my sources:

https://www.britannica.com/summary/The-Enlightenment-Timeline

https://www.famousscientists.org/timeline-scientific-revolution/

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Galileo SCALA/Art Resource, New York
Galileo's Sidereus Nuncius ( The Sidereal Messenger) is published. In the book Galileo describes his discoveries of four moons revolving around the planet Jupiter. These discoveries support the Copernican heliocentric theory, which proposed that Earth and the other planets revolve around the Sun. (For centuries astronomy had been based on Ptolemy's theory that Earth was the center of the universe and motionless.) The book is one of the scientific texts considered foundational to the Enlightenment.

John Locke completes a major work in political philosophy, Two Treatises of Government. In this work he defends a doctrine of natural rights and a conception of political authority as limited and conditional on the ruler's fulfillment of his obligation to serve the public good. A classic formulation of the principles of political liberalism, this work will later influence the American and French revolutions.

The Deistic philosopher John Toland publishes Christianity Not Mysterious. In this work he seeks to show that "there is nothing in the Gospels contrary to reason, nor above it." Any doctrine that is really above reason, he argues, would be meaningless to humans.

Montesquieu© Everett Historical/Shutterstock.com
Montesquieu publishes his first book, Lettres persanes ( Persian Letters). The book gives a brilliant satirical portrait of French and, particularly, Parisian civilization, supposedly seen through the eyes of two Persian travelers. The work mocks the reign of Louis XIV, which had recently ended; pokes fun at all social classes; and discusses the theories of Thomas Hobbes relating to the state of nature. It also satirizes Roman Catholic doctrine and is infused throughout with a new spirit of vigorous, disrespectful, and iconoclastic criticism.

Voltaire publishes Lettres philosophiques, in which he speaks out against established religious and political systems. The work creates an uproar, and he is forced to flee Paris.

In Systema Naturae ("The System of Nature") Swedish naturalist Carolus Linnaeus presents a classification of three kingdoms of nature: stones, plants, and animals. Each kingdom is subdivided into classes, orders, genera, species, and varieties. This system is still used in biology, though it has been revised over the years.

Discover the Enlightenment's influence on biologic categorization, encyclopedias, and literature

Encyclopædia Britannica, Inc.

The first volume of the French Encyclopédie appears. This encyclopedia, created by the philosophes, is one of the principal works of the Enlightenment. Its compilation of available human knowledge reflects an optimism toward scientific and human progress. The encyclopedia will eventually total 35 volumes.

Voltaire publishes his best-known work, the satirical novel , an undisputed masterpiece of the 18th century.

Jean-Jacques Rousseau Courtesy of the Musée d'Art et d'Histoire, Geneva; photograph, Jean Arlaud
Jean-Jacques Rousseau publishes Du Contrat social ( The Social Contract) in France. In his work Rousseau challenges the traditional order of society based on binding laws handed down by rulers or the church. He argues instead that laws are binding only if the general will of the people supports them within a type of social contract.

Declaration of Independence Yale University Art Gallery

The Declaration of Independence is approved by the Continental Congress meeting in Philadelphia. The document announces the separation of 13 North American British colonies from Great Britain. Thomas Jefferson was largely responsible for the writing of the document. It begins with a declaration of individual rights and then lists the alleged acts of tyranny by George III that form the colonies' justification for seeking independence. The document reflects many Enlightenment ideals. These include government by consent of the governed, unalienable human rights, and the promotion of life, liberty, and the pursuit of happiness.

The efforts of the French regime to increase taxes on the privileged classes initiates a crises, which marks the beginning of the French Revolution.

In his essay Sur l'admission des femmes au droits de la cité ( On the Admission of Women to the Rights of Citizenship), the marquis de Condorcet argues that the widely shared assumption that the natural rights of men are based on their capacities for reason and moral action logically implies that women possess the very same rights. He is one of the few men during the Enlightenment to advocate that women be granted full equality and citizenship in society.

Thomas Paine publishes The Rights of Man in support of the French Revolution and republicanism.

Encyclopædia Britannica, Inc.

During the period of the French Revolution known as the Reign of Terror, harsh measures are taken against those suspected of being enemies of the revolution. A wave of executions takes place in Paris. In the provinces representatives on mission and surveillance committees institute local terrors. At least 300,000 suspects are arrested during the Reign of Terror. About 17,000 are officially executed, and perhaps 10,000 die in prison or without trial.

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Timeline of significant events related to the Enlightenment. The main goal of this wide-ranging intellectual movement was to understand the natural world and humankind's place in it solely on the basis of reason. The movement claimed the allegiance of many thinkers in Europe during the 17th and 18th centuries.