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Black Plague (1347-1351): 200 million deaths.

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Black Plague (1347-1351): 200 million deaths.

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The most deadly pandemic with the most lasting impact on human history is considered. It is believed that the outbreak began in Central Asia, and from there passed the Silk Road until reaching the Crimean peninsula. Housed in the fleas of black rats, it spread throughout Europe.

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The lack of treatment of human excrement and the absence of clean water are mainly responsible for the spread of cholera. Between 1817 and 1923, the first six pandemics of this disease occurred in different parts of the Asian continent.

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The scientists consider that it originated in Africa, with transmission between primates and humans. The virus and vector, which is the Aedes aegypti, a kind of mosquito, were brought to the Americas by slave trade ships. During the 19th century, major outbreaks occurred in America and Europe.

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HIV/AIDS (1981-present): 25-35 million deaths.

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HIV/AIDS (1981-present): 25-35 million deaths.

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Caused by a human immunodeficiency virus that originated in primates in Central and West Africa in the early 20th century. While several subgroups of the virus acquired the ability to infect humans, the pandemic had its origins in the emergence of a specific strain. There are currently 37.9 million people infected with HIV worldwide, and in 2018 alone 770,000 people died from HIV.

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It was the second pandemic caused by the H1N1 influenza virus, almost a century after the Spanish flu. However, it is a new strain of H1N1, which originated when avian, swine and human influenza viruses were combined with a Eurasian swine flu virus, which is why it is known as swine flu.
The outbreak appeared in pigs in a region of central Mexico, and from there it spread.

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Used Acute Respiratory Syndrome a disease caused by a coronavirus other than the cause of COVID-19, SARS-CoV. Between November 2002 and July 2003, an outbreak in southern China ended with 8,098 infected people in 17 countries, although most cases were recorded in China and Hong Kong.

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It is a viral hemorrhagic fever affecting humans and other primates. The 2014 was the most widespread outbreak of the disease in history. The first cases were recorded in Guinea in December 2013, and from there it spread to Liberia and Sierra Leone, where it caused devastating human and material effects. The fatality rate among hospitalized patients was between 57 and 59 percent.

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COVID-19 is the most recently discovered infectious disease caused by coronavirus. Both this new virus and the disease it causes were unknown before the outbreak erupted in Wuhan, China, in December 2019. COVID-19 is currently a pandemic affecting many countries around the world. The disease is mainly spread from person to person by droplets that come out of the nose or coughing, talking or sneezin.