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Drugs can alter important brain areas that are necessary for life-sustaining functions and can drive the compulsive drug abuse that marks addiction. Drugs are chemicals that affect the brain by tapping into its communication system and interfering with the way neurons normally send, receive, and process information. Some drugs, such as marijuana and heroin, can activate neurons because their chemical structure mimics that of a natural neurotransmitter. The feelings that drug abusers get can cause them to be addicted, as they want to feel that sensation over and over.

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CNS depressants is a sedative that slows the activity of the central nervous system. It is used to slow nerve activity, relax muscle tension, lower alertness, and cause drowsiness. The feeling of everything being "slowed" down could cause people to become addicted to the sensation.
CNS depressants are essentially sedatives or tranquilizers that slow down the brain activity.
Common street names:Reds, Red Devils, RD's, Fender Benders, Yellows, Yellow Jackets, Blues, Blue Heavens
CNS depressants are pills, so they are swallowed.
Short-term effects: Slows normal brain functions, gives a drowsy feeling, but over time the effects fade as body builds tolerance.
Long-term effects: Addiction can result, withdrawal can be painful, and the drug may cause seizures and death.

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Methamphetamine produces a "high" or rush that often makes users addicted to it. However, when the rush wears off, users become confused, shaky, anxious, irritable, and violent.
Some street names are meth, crank, crystal, or ice
Methamphetamine comes in several forms and can be smoked, inhaled (snorted), injected, or orally ingested
Short term effects include: increased respiration, elevated body temperature, convulsions, and stroke
Long term effects include: Psychotic behavior, memory loss, aggression, brain damage, heart damage, severe tooth and gum disease, and stroke

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Lysergic acid diethylamide, or LSD, is a hallucinogen that can either stimulate or depress the central nervous system. Abusers experience hallucinations in which they may see colorful visions and mistakenly feel they have superhuman powers
Some street names are acid, blaze, blotter
LSD is usually taken orally
The most common short-term effects of LSD use include, but are not limited to:

High-blood pressure

Hallucinations; an individual may taste, smell or see things that are not there

Becoming out of touch with reality

Dilated pupils

Some of the long-term LSD effects are:

Drug tolerance

Flashbacks

Delusional behaviors

Vision problems

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Marijuana is the leaves from the hemp plant cannabis sativa that changes the way information reaches and is acted upon by the brain.
Street names of Marijuana are pot, dope, weed, or grass
Marijuana can be smoked in a pipe, blunt ,, or mixed with food
Short term effects: distorted perceptions, difficulties with thinking, increased heart rate
Long term effects: short term memory, loss motivation, certain cancers

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Inhalants are breathable chemical vapor that produces mind-altering effects. Abusing inhalants may produce brief feelings of excitement or giddiness.
Street names: Laughing gas (nitrous oxide), Snappers (amyl nitrite), Poppers (amyl nitrite and butyl nitrite), Whippets (fluorinated hydrocarbons), Bold (nitrites), and Rush (nitrites)
People who use inhalants breathe in the fumes through their nose or mouth, usually by: “sniffing” or “snorting” fumes from container.
Common symptoms of inhalant intoxication include the following:

Euphoria

Slurred speech

Lack of coordination

Common signs of addiction to inhalants include the following:

An unusual smell of chemicals on the breath or clothing

Household chemical stains on clothing, face or hands

Slurred speech

Apparent intoxication or disorientation