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morphine was expanded into an array of morphine-like medications known collectively as the opioids.

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German pharmacist, Friedrich Serturner isolated morphine from opium

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Benefit of Morphine without the negative effect of Beta Arrestin.

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Opium was used after surgery to ease pain

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In a new trial 330 bunionectomy patients received Oliceridine, morphine or a placebo after their surgery.

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In a new trial 330 bunionectomy patients received Oliceridine, morphine or a placebo after their surgery.

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It is urgent as we need to find an alternative to morphine

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It is urgent as we need to find an alternative to morphine

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Black Marketing of new compounds which may lead to backslashing of regulations

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Black Marketing of new compounds which may lead to backslashing of regulations

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The opioid could be harmful or addictive 

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The opioid could be harmful or addictive 

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Roman physicians mixed opium with wine as an anaesthesia before limb amputation

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Oliceridine is the only opioid compound of its kind to be tested on humans.

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Oliceridine is the only opioid compound of its kind to be tested on humans.

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-ease pain
-treat disease
-generate euphoria

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Safety should be questioned when new drugs are created

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Safety should be questioned when new drugs are created

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New drugs should be assumed to have some risk of addiction

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New drugs should be assumed to have some risk of addiction

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For more than 200 yrs, doctors have been using morphine as a pain killer, a drug isolated from opium poppy.

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For more than 200 yrs, doctors have been using morphine as a pain killer, a drug isolated from opium poppy.

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Problem can occur during clinical trials

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Problem can occur during clinical trials