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Centers for Disease Control and Prevention

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Centers for Disease Control and Prevention (CDC)

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This video contains information about the causes of Fragile X Syndrome. Comments on this video are allowed in accordance with our comment policy: http://www.cdc.gov/SocialMedia/Tools/CommentPolicy.html This video can also be viewed at http://www.cdc.gov/NCBDDD/video/fxs/index.html

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"A recent study of 6,747 people found that 1 in 151 women and 1 in 468 men had the premutation. People with the premutation might not have any symptoms of Fragile X"

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"Fragile X syndrome is inherited in an X-linked dominant pattern. A condition is considered X-linked if the mutated gene that causes the disorder is located on the X chromosome, one of the two sex chromosomes. (The Y chromosome is the other sex chromosome.) The inheritance is dominant if one copy of the altered gene in each cell is sufficient to cause the condition."

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"FMR1 gene on the X chromosome, known as a gene mutation. The X chromosome is one of two sex determining chromosomes. When the gene lengthens it switches off production of a protein that is involved in brain development and other functions."

"The X chromosome contains between 6 and 50 repeats of a gene (the FMR1 gene) responsible for producing a protein vital for normal brain development."

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"genetic testing"

"condition achieve"

"highest potential in terms of cognition, behavior, and more"

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·        " developmental delays, such as taking longer than normal to sit, walk, or talk compared with other children of the same age"

"stuttering"

·         "intellectual and learning disabilities, like having trouble learning new skills

general or social anxiety"

·         "autism"

·         "impulsiveness"

"attention difficulties"

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https://fragilex.org/learn/treatment-and-intervention/

https://ghr.nlm.nih.gov/condition/fragile-x-syndrome

http://readingroom.mindspec.org/?news-item=drug-therapies-show-success-for-fragile-x-syndrome&gclid=EAIaIQobChMIz_OP1caM2gIVl47ICh1KggYWEAAYAiAAEgK2efD_BwE

https://www.nichd.nih.gov/health/topics/fragilex/conditioninfo/commonsymptoms

https://www.healthline.com/health/fragile-x-syndrome

https://www.sharecare.com/health/genetic-disorders/can-fragilex-syndrome-be-prevented

https://www.whatisepigenetics.com/epigenetics-may-provide-relief-fragile-x-syndrome-intellectual-disorders/

https://youtu.be/auIwEV1SiBQ

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"While there is currently no cure for Fragile X syndrome (FXS), there are many areas of treatment and intervention that can improve the lives of affected individuals and their families. Given the proper education, therapy, and support, all persons with FXS can make progress.Most children with FXS qualify for special education services. Education can be complemented by a variety of therapies that will help your child become more independent in the transitions from childhood through adolescence and into adulthood."

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These problems can range from the mild, such as learning disorders or problems with mathematics, to the severe, such as an intellectual or developmental disability.

The syndrome may affect the ability to think, reason, and learn.

Because many people with Fragile X also have attention disorders, hyperactivity, anxiety, and language-processing problems, a person with Fragile X may have more capabilities than his

·         Most infants and younger children with Fragile X don’t have any specific physical features of this syndrome. When these children start to go through puberty, however, many will begin to develop certain features that are typical of those with Fragile X.

·         These features include a narrow face, large head, large ears, flexible joints, flat feet, and a prominent forehead.

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Fragile X syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females.

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anthony Strom (genetic counselor)