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Step 1
Select 3 salts that result in change of pH

What parameters would C6H5COO–Na+.½H2O and C6H5COO–.His  be different compared to C6H5COOH (the parent)?

What kind of tendency do Inorganic salts with high MW have?

What are popular salts formers?

Which type of salts tend to form more soluble anhydrates than hydrates?

What are the favourable properties of hydroxyacids to improve drug solubility?

How erythromycin stearate contribute to improvements in drug formulation?

Which are properties of insoluble salts?

What are the commonly used cations? Why they are used in many formulations?

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Hi dr. Just want to inform that  the videos for slide 17-20 (about cations ) in bit.ly/ladme2  is  somehow unavailable. Thank you.

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What parameters would C6H5COO–Na+.½H2O and C6H5COO–.His  be different compared to C6H5COOH (the parent)?

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There are 4 steps in solving problems in drug solubility and/or permeability.
The task:
1. Each member of the HOME group is responsible for 1 step. Decide among yourself who takes which step.
2. Then, go to the EXPERT group to discuss each step (20 mins).
3. Return to the HOME group to explain to your HOME group members what you've discovered about your own Step. (30 mins)
Mission: To win the toughest QUIZ of the semester😉
Link to resouces: bit.ly/ladme2

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Chong Yung Chin - task 1
Anudiinee A/P Kobu - task 2
Chan Siong Yeow - task 3
Edward Tan Kong Weng - task 4

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Read the given chapter 43
Expert group: Discuss with members;
Home group: Explain to members.
Topic: INN Stem; Pros and Cons
What is a stem? What's the functions?
What is the stem for Kanamycin?
Go through the stems in the given chapter - and see many you can identify with the drug functions.

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Read the given chapter 43
Expert group: Discuss with members;
Home group: Explain to members.
Topic: INN
What is INN?
Why do we need INN?
How is INN being selected?
How is INN being used?

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Watch https://youtu.be/X39W2Oqd35I
Expert group: Discuss with members;
Home group: Explain to members
1. Why do we need to classify drugs?
2. What are the uses of the type of classification mentioned in the video?
3. What are other ways to classify drugs?

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Read the given chapter 43
Expert group: Discuss with members;
Home group: Explain to members
Topic: Tradename; Pros and Cons
What is a tradename? Why tradenames? What are the pros and cons?

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1. Adlina task 4
2. Wanyee task 3
3. Dian task1
4. Nadia task2
5. Tey Yan Teng task 1

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1. Tey Yan Teng
2. Syazlin
3. Yekahshene
4. Siti Kadhijah

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1- Nur Shahira
2- Hoe Khai
3- Sarvheenee
4- Syazlin
5- Siti Khadijah

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Task 1 -   Najihah Adilah
Task 2 - Shantini
Task 3 - Raihan
Task 4 - Nurlisya

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1. Loke Cheow En
2. Goh Gee Seng
3. Wong Zhi Chin
4. Sim Yee Shan
5. Kirtana A/P Supramania.

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Task 1-teh chye teik
Task 2-sheryl
Task 3-najiha
Task 4-salma

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Task 1-Eddy
Task 2-Wei Kit
Task 3-Anis
Task 4-Karyee

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Some questions to guide you in the Steps

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Some questions to guide you in the Steps

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Step 1

Select 3 salts that result in change of pH

What parameters would C₆H₅COO–Na⁺.½H₂O and C₆H₅COO–.His  be different compared to C₆H₅COOH (the parent)?

What kind of tendency do Inorganic salts with high MW have?

What are popular salts formers?

Which type of salts tend to form more soluble anhydrates than hydrates?

What are the favourable properties of hydroxyacids to improve drug solubility?

How erythromycin stearate contribute to improvements in drug formulation?

Which are properties of insoluble salts?

What are the commonly used cations? Why they are used in many formulations?

__________________________________

Step 2 Co-solvents

What are some pharmaceutically acceptable co-solvents and surfactants?

How do they work to help improve drug solubility?

__________________________________

Step 3

Water-soluble complexes with cyclodextrins

What is a cyclodextrin?

What are the types? How each type is being used to improve drug solubility?

Give some examples of cyclodextrin-complexed drug

———————————————

Step 4

What are the benefits?

What are the categories of water-solubilising groups?

What are water-solubilising groups?

Where to attach these groups?

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Task 1-Foo seng
Task 2-Adib
Task 3-Xing Zen
Task 4-yi xin

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Task 1 - Najihah
Task 2 - Sarah Amni
Task 3 - Nabilah
Task 4 - Sorfine

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1. Adlina task 4
2. Wanyee task 3
3. Dian task1
4. Nadia task2

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Task 1 : xiao syuen
Task 2 : cayenne
Task 3 : mun qi
Task 4 : dyllan

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Sherring-task 1
Shafiqah-T2
Wen Rui-T3
Hui Min-task 4

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1.Ahmad Ilman (1)
2.Chan Sze Yan(3)
3.Darlia Syafika (4)
4.Ashvaani Nadarajan(2)

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Huda-1
Aqilah-2
Farahani-3
Arif-4

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Mohammad Ikhwan Hakim Bin Ishak -task 1
Nasiha sufina-task2
Xian Jun- task 3
Aina- task 4

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Amazing 4
Safi- task 1
Brenda-task 2
Angell-task 3
Dina-task 4

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Ng You Chun (T1)
Amir (T2)
Nazirah (T3)
Nur Amirah (T4

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Sapphire- 1.Syuhada, 2.Jia Huey, 3.Shamila, 4.Siti

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Task 1- Faizanah
Task 2 - Hanis
Task 3 - Pei Wern
Task 4 - Guo Jian

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Task 1 - ainul
Task 2 - darren
Task 3 - wei ning
Task 4 - asiah

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hafiz - task 1
zahir - task 2
chai hwai - task 3
dila - task 4

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Task 1 - Tina
Task 2 - Jia Wen
Task 3 - Yusrina
Task 4 - Wan Ting

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Task 1-Jason
Task 2-Khai hang
Task 3-Kaizhah
Task 4-Fatin

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Farah Task 1
Nicole Task 2
Ain Task 3
Rohayu Task 4

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Wan-Task 1
Li wen-Task 2
Thanes-Task 3
Ee Theng-Task 4

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Irshad - Task 1
Pui Yan - Task 2
Jia Yi - Task 3
Saravana - Task 4

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What is the role of chemistry in drug design? Explain to your home group members.

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What is the role of chemistry in pharmacokinetic phase? i.e. in the drug journey. Explain to your home group members.

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What is the role of chemistry in Formulation and Drug Delivery. Explain to your group member. Explain to your home group members.

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What is a drug? Definition of a drug
What are characteristics of a drug? (At least 5 characteristics)
Can a drug be considered a poison? Any similarities and difference?
Explain to your home group members.

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What is the role of chemistry in Formulation and Drug Delivery? Explain to your home group member.