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Epigenetics is the study of changes in gene function that are heritable and cannot be attributed to alterations in the DNA sequence. The term epi means above. It is a Greek prefix. It is also defined as above the DNA base sequence. In general terms it can be compared to the accents of the words where the DNA is the language and the modifications are the accents.

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Epigenetics, also epigenome, is the study of the mechanisms that regulate the expression of genes without a modification in the DNA sequence that composes them.

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Epigenetics (also sometimes called epigenomics) is a field of study focused on changes in DNA that do not involve alterations to the underlying sequence. The DNA letters and the proteins that interact with DNA can have chemical modifications that change the degrees to which genes are turned on and off.

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Certain epigenetic modifications may be passed on from parent cell to daughter cell during cell division or from one generation to the next. The collection of all epigenetic changes in a genome is called an epigenome.

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The DNA letters in a gene, as well as the proteins that interact with the established gene, are not empty. Both are decorated with chemical modifications that regulate how, where, and when the gene is turned on and off.