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Lea Michele has PCOS. Polycystic ovary syndrome (PCOS) is a common hormonal disorder that may be characterized by an abnormal menstrual cycle, excessive facial or body hair, and numerous tiny cysts in the ovaries. The cause of polycystic ovary syndrome isn't well understood, but may involve a combination of genetic and environmental factors.

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Larry King has diabetes mellitus type II. Diabetes Mellitus Type II is diabetes mellitus in which insulin production may be normal, but the body cannot use the insulin efficiently nor can it increase insulin production sufficiently to compensate. With type 2 diabetes, the body either doesn't produce enough insulin, or it resists insulin.

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Jay Cutler has diabetes mellitus type I. Diabetes Mellitus Type I is diabetes mellitus in which insulin is deficient due to abnormalities in the islets of Langerhans, causing hyperglycemia. It typically appears in adolescence.

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Zoe Saldana has hyperthyroidism. Hyperthyroidism is the overproduction of a hormone by the butterfly-shaped gland in the neck (thyroid). Hyperthyroidism is the production of too much thyroxine hormone. It can increase metabolism.

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Hillary Clinton has hypothyroidism. Hypothyroidism is a condition in which the thyroid gland doesn't produce enough thyroid hormone. Hypothyroidism's deficiency of thyroid hormones can disrupt such things as heart rate, body temperature, and all aspects of metabolism. Hypothyroidism is most prevalent in older women.

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Goiter is an enlargement of the thyroid gland. A goiter commonly develops as a result of iodine deficiency or inflammation of the thyroid gland. Not all goiters cause symptoms. Symptoms that do occur might include swelling, and cough. Rarely, symptoms may include throat tightness or trouble breathing.

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Sofia Vergara has thyroid cancer. Thyroid Cancer is a cancer of the thyroid, the butterfly-shaped gland at the base of the neck.

The cause of thyroid cancer is poorly understood, but may involve a combination of genetic and environmental factors.

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Tara Palmer-Tomkinson has prolactinoma. Prolactinoma is a non-benign tumor of the pituitary gland. The hormone-producing gland in the brain (pituitary gland) overproduces prolactin, decreasing the levels of some sex hormones. It's caused by a noncancerous tumor on the gland.

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Peter Dinklage has dwarfism. Dwarfism is a genetic or medical condition of being abnormally small or short, usually defined as an adult height of 4’10” (1.47 meters) or less. Dwarfism has many causes, one of which is endocrine dysfunction resulting from a lack of GH. Dwarfism can be either genetic or the result of an endocrine disorder that causes undersecretion of GH.

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André René Roussimoff has gigantism. Gigantism is an excessive growth of body parts, often due to hypersecretion of GH. It causes excessive growth in height, muscles, and organs, making the child extremely large for his or her age.

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Gina Rodriguez has Hashimoto Disease. Hashimoto Disease is a chronic autoimmune form of thyroiditis. It results in hyposecretion of thyroid hormones. Initially, inflammation of the thyroid causes a leak resulting in excess thyroid hormones (hyperthyroidism). Over time, the inflammation prevents the thyroid from producing enough hormones (hypothyroidism).

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Missy Elliott has Grave’s Disease. Grave’s Disease is an autoimmune condition that results in hyperthyroidism. The thyroid overproduces hormones. The condition is more common in women under age 40. It is characterized by blushing eyeballs and an enlarged thyroid gland.

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King Henry VIII has Cushing’s Disease. Cushing’s Disease is a condition resulting from the hyper secretion of cortisol. It may be cause by a tumor or prolonged use of steroids. Cushing’s syndrome is characterized by weakness; thin, easily bruised skin; hypertension; and weight gain. Cushing’s syndrome can cause severe edema and weight gain, as well as hypertension.

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John F Kennedy has Addison's Disease. Addison’s Disease is a disease resulting from insufficient secretion of cortisol and sometimes aldosterone. It is characterized by progressive anemia, hypotension, hypoglycemia, fatigue, increased skin pigmentation, join pain, and loss of appetite. Addison’s disease affects several different body systems.