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Also known as the Adrenergic System: "Fight, Flight, Fright"

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Also known as the Cholinergic System: "Rest and Digest"

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Norepinephrine (NE) - released from the Adrenal Medulla

Epinephrine (EPI) - released from the Adrenal Medulla

Dopamine - relaseed from the Hypothalamus

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Alpha-1  - effects the smooth muscle (contraction), the eyes (pupil dilation), and the arteries/veins (vasoconstriction)

Alpha-2 - effects the adrenal gland (releases norepinephrine)

Beta-1 - effects the heart (increasing force contraction, conduction, and heart rate)

Beta-2 - effects the smooth muscle (relaxation), the lungs (bronchodilation), the uterus and skeletal muscles (relaxation), as well as the coronary arteries (vasodilation)

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Acetylcholine (ACH) - released at ganglia from the presynaptic nerve endings

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Muscarinic - effects cardiac muscle (decreased heart rate), smooth muscle (bronchoconstriction, increased digestion), and glands

Nicotinic 1 (Nn) - effects ganglia at the parasympathetic / sympathetic nerves

Nicotinic 1 (Nm) - somatic, neuromuscular junction (if stimulated muscle contracts)

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1. Alpha-1 Adrenergic Agonists = Alpha-1 receptor (muscle contraction, vasoconstriction)

2. Adrenergic Agonists = Alpha and Beta receptors (vasoconstriction and cardiac stimulant)

3. Alpha-1 Adrenergic Blocking Drugs = Alpha-1 receptor (muscle relaxation and vasodilation)

4. Beta-1 Adrenergic Agonists = Dopaminergic receptors (kidneys effected), Beta-1 receptors (heart effected), Alpha-1 receptors (vasoconstriction)

5. Beta-2 Adrenergic Agonists = Beta-2 receptors (bronchodilation and uterine relaxation)

6. Selective Beta-1 Blockers = Beta-1 receptors (decreased heart function)

7. Nonselective Beta Blockers = Beta 1 and 2 receptors (effects cardiac output)

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1. Cholinergics/ Parasympathomimetics (Direct) =
directly binds to receptor; mimics ACH

2. Cholinergics / Parasympathomimetics (Indirect) =
inhibits acetylcholinesterase; destroys ACH

3. Anticholinergics / Parasympatholytics = binds to cholinergic receptors (acts as blocker)

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1. Alpha-1 Adrenergic Agonists =
-ephedrine
-phenylephrine (Neo-Synephrine®)

2. Adrenergic Agonists =
-epinephrine (Adrenalin®)

3. Alpha-1 Adrenergic Blocking Drugs =
-prazosin (Minipress®)
-terazosin (Hytrin®)
-doxazosin (Cardura®)

4. Beta-1 Adrenergic Agonists =
-dobutamine

5. Beta-2 Adrenergic Agonists =
-formoterol (Foradil®)
-albuterol (Proventil®/Ventolin®)
-terbutaline (Brethine®)

6. Selective Beta-1 Blockers =
-atenolol (Tenormin®)
-metoprolol (Lopressor®)

7. Nonselective Beta Blockers =
-nadolol (Corgard®)
-propranolol (Inderol®)
-timolol (Blocadren®)

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1. Cholinergics/ Parasympathomimetics (Direct) =
-acetylcholine
-pilocarpine (Pilocar®)
-bethanechol (Urecholine®)

2. Cholinergics / Parasympathomimetics (Indirect) =
-neostigmine (Prostigmin®)

3. Anticholinergics / Parasympatholytics =
-atropine
-dicyclomine (Bentyl®)

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all information was found in the lecture videos / lecture powerpoints

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all information was found in the lecture videos / lecture powerpoints