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Revisit this site to read through your classmates' posts. As you review these, consider:
1. What do you agree on?
2. Are there divergent views, and if so, what does that mean for the science?
3. What is a new insight that you hadn't considered?

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Translational science is  looking at and studying the implications of the application of EBP. 

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Translational science is  looking at and studying the implications of the application of EBP. 

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Translational methods are the research aspects the T0-T4 phases of research. 

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Translational methods are the research aspects the T0-T4 phases of research. 

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TM-The methods used in studying the SSRI's for depression. The clinical trials portion, from animal to human to actual practice(If I have all this backwards let me know)

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TM-The methods used in studying the SSRI's for depression. The clinical trials portion, from animal to human to actual practice(If I have all this backwards let me know)

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EBP-SSRI's for use of depression

TS-Star D Study for depression efficacy after they were implemented into practice

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Translational science is the process that occurs in order to progress from observation to intervention to EBP.

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Translational methods (TM) are those that are instituted (bundles, protocols) as the result of translational science and the continued study of the best EBP.

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Ventilator-associated pneumonia (VAP ) and the VAP bundle.
VAP bundle consisting of HOB 30-45 degrees, GI prophylaxis, DVT prophylaxis, sedation vacation, readiness for extubuation is an example of a TM.
Studying VAP, risks, preventive measures in a controlled study is TS. EBP is instituting it into practice and continuing to evaluate its effectiveness and if changes might be needed. If questions arise, the process of TS can start over.

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The study of the dissemination of knowledge to move new understandings from the acceptance stage to the adoption stage of new practices.

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Ways that practitioners are moved from the acceptance of new understandings to the adoption of these practices.

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The evidence based practice (EBP) of intentionally teaching clinical judgment to undergraduate nursing students would employ translational science (TS) to determine how to best help clinical instructors to apply the intentional teaching of clinical judgment to students. For example, is it most efficient to offer in-services to teach the clinical instructors and then to follow this up with mentoring? Studies about this aspect would be considered translational science. And the translational methods in this case would be the practices that the clinical instructors would use to teach clinical judgment to the students, such as coaching, concept-mapping or reflection.

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Taking observations from the community and/or practice and turning them into interventions to address and better an issue. This can be considered the bridge between the science and medical fields.

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is usually a multi-faceted process where EBP can be taken to the bedside utilizing a specific translation method that is appropriate (and sometimes not appropriate) for the population in which it is intended to serve.

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Per the CDC, 75% of UTIs that are acquired in the hospital are associated with a urinary catheter. EBP has shown that utilizing CHG wipes and a foam cleanser to the catheter tubing has reduced CAUTI and is now a part of the CAUTI bundle in many facilities. Prior to the initiation of this standard, translational science was utilized to determine the best intervention in preventing CAUTI. Interventions such as CHG wipes, foam cleansers, securing devices, external catheters and assessment of catheter says was all analyzed to create a bundle for CAUTI prevention. For dissemination - translational methods were utilized to include education via classes and online learning modules, chart audits, and checklists to determine implementation and compliance.

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EBP is the application of evidence in practice- almost like an action. Translation science is the study of these implementations that can then affect practice (Titler, 2014)

Titler M. G. (2014). Overview of evidence-based practice and translation science. The Nursing clinics of North America, 49(3), 269–274. https://doi.org/10.1016/j.cnur.2014.05.001

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To segway from Leighann mentioning translation science (TS) as a bridge- There is a gap between evidence based practice (EBP) and actual application. Our text explains lack of resources as the most common barrier (White, Dudley-Brown, & Terhaar, 2021). TS helps to bridge the gap-  TS helps to "clarify what implementation strategies work for whom, in what settings, and why" (Titler, 2018).

Titler M.G. (2018). Translational research in practice: an introduction. Online Journal of Issues in Nursing, 23(2). 1-1.https://doi.org/10.3912/OJIN.Vol23No02Man01

White, K.M., Dudley-Brown, S., Terhaar, M.F. (2021) Translation of Evidence into Nursing and Healthcare. Springer publishing.

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Our text explains that translation methods refer to "strategies and approaches" that can move science into practice (White, Dudley-Brown, & Terhaar, 2021).

White, K.M., Dudley-Brown, S., Terhaar, M.F. (2021) Translation of Evidence into Nursing and Healthcare. Springer publishing.

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EBP is a process or an action in which the provider gathers information (ideally from quality research) and implements it in their medical or nursing practice.  The way I think about it EBP is the "what" in comparison to translation science and translation methods.

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Translation science is a field of research that is dedicated to studying the process by which research findings are implemented as interventions.  Translation science asks how does knowledge become best practice (EBP). I think of TS as the "why" in relationship to EBP and translation methods.

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Translation methods are the means by which the knowledge from science becomes an intervention. In comparison to EBP and TS, TM is the "how".

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In my setting of primary care, one example is the routine use of dipstick UAs for pregnant patients to screen for signs of preeclampsia.  Evidence demonstrates that the use of this test as a routine intervention is ineffective because a UA would show late signs of preeclampsia.  Ordering UAs for symptomatic patients is superior to routine UAs at every prenatal appointment (EBP).  A study that looks at the barriers and facilitators of implementing this best practice is an example of translation science (TS).  Providing education to providers who take care of prenatal patients in order to reduce the use of routine UAs is an example of the use of translation methods (TM).

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Methamphetamine abuse is common in my community. I have many patients who are suffering from heart disease secondary to meth abuse. Sadly, medication assisted treatment for meth use is still being studied. A fairly recent study showed that injectable naltrexone (Vivitrol) AND Wellbutrin combined was effective for assisting patients with methamphetamine cessation. Implementing this into our clinic would be evidence based practice (EBP).  The ADAPT-2 study conducted from from 2017 to 2019 at nationwide community treatment programs with 403 adult volunteers ages 18 to 65 years with moderate to severe methamphetamine use disorder. This study is the translation science (TS) piece. Educating providers on this treatment plan as well as moving forward with our screening for meth use would be translation methods (TM). At our community health clinic we screen individuals for substance abuse which would be a first step in a method to implement a treatment plan. We then have behavioral health clinicians assess the patient and then as a provider I can make an individualized plan for treatment- including same day vivitrol injection (if liver enzymes are within normal limits) as well as Wellbutrin RX. We then have close follow up in 2 weeks.

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Evidence Based Practice (EBP) is the use of the most current and best evidence along with clinical expertise to guide healthcare decisions (Titler, 2018).
Titler, M. G. (2018). Translational research in practice: An introduction. The Online Journal of Issues in Nursing, 23(2).

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Translational science looks at which approaches will work to encourage evidence based practice (Titler, 2018).

Titler, M. G. (2018). Translational research in practice: An introduction. The Online Journal of Issues in Nursing, 23(2).

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Translation methods is how EBP is applied in order to improve practice.

Titler, M. G. (2018). Translational research in practice: An introduction. The Online Journal of Issues in Nursing, 23(2).

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In my clinical area,

EBP: Based on the STOP-IT trial, once there is source control from an infective source (like a perforated gallbladder that has been removed), we treat with 4+1 days of antibiotics.

Translational science: the STOP-IT trial looked at patients with complicated intraabdominal infections and tested 14 days vs 5 days of antibiotics after source control was achieved

Translational methods: Disseminating the information to providers about the lack of need for extended antibiotics once source control is surgically achieved

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Erin Christiansen          Evidence based practice (EBP) is when policy and practices are based on the best available known data.  EBP identifies specific policies or clinical questions, generates knowledge and evidence, tests the knowledge and/or evidence in practice, and collects data to support its effectiveness (Pearson et al., 2012).   Translational science is the act of translating EBP into practice.               Reference Pearson, A., Jordan, Z., & Munn, Z. (2012). Translational Science and Evidence-Based Healthcare: A Clarification and Reconceptualization of How Knowledge Is Generated and Used in Healthcare. Nursing Research and Practice, 2012, 1–6. https://doi.org/10.1155/2012/792519   

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Erin Christiansen          Evidence based practice (EBP) is when policy and practices are based on the best available known data.  EBP identifies specific policies or clinical questions, generates knowledge and evidence, tests the knowledge and/or evidence in practice, and collects data to support its effectiveness (Pearson et al., 2012).   Translational science is the act of translating EBP into practice.               Reference Pearson, A., Jordan, Z., & Munn, Z. (2012). Translational Science and Evidence-Based Healthcare: A Clarification and Reconceptualization of How Knowledge Is Generated and Used in Healthcare. Nursing Research and Practice, 2012, 1–6. https://doi.org/10.1155/2012/792519   

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Translational science does not create, gather, or test the evidence or knowledge like EBP does. Rather translational science is the process of taking EBP and putting into practice for specific populations.

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I like the example White, Dudley-Brown, & Terhaar (2021) gave. They described translational methods as translating the evidence "from the bench to the bedside." The strategies, theories, or approaches used to get from the bench to the bedside are the methods in translational methods (White, Dudley-Brown, & Terhaar, 2021).

Reference
White, K.M., Dudley-Brown, S., Terhaar, M.F. (2021) Translation of Evidence into Nursing and Healthcare. Springer publishing

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Erin Christiansen
An example of EBP, TS, and TM can be demonstrated in my project.
My collecting data and researching of tested and proved orientation and training new hire programs is EBP.  Translating my EBP from research into practice is TS.  TM is the theory of change I will plan on using to implement the EBP.