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The amides are derivates of carboxylic acids in which a nitrogen group replaces the hydroxyl group.

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methanamide (formide)

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ethanamide (acetamide)

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butamide (butyramide)

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Proteins, from the keratin in your hair and nails to the enzymes catalysing your cellular reactions, are all polyamides.

Plastics and synthetic fibres such as nylon and Kevlar are also types of polyamides. So too are natural fibres like silk and wool.

They play a role in the pharmaceutical industry - paracetamol, penicillin, and LSD are all examples of amides.

The organic molecule urea, a natural waste product that we excrete in urine, is also an amide. It is produced industrially for use in fertilisers and animal feeds.

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The characteristic reaction of covalent amides is hydrolysis (a chemical reaction with water), by which they are converted to acids and amines; this reaction ordinarily is slow unless it is catalyzed by a strong acid, an alkali, or an enzyme. Amides also can be dehydrated to nitriles.

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Only formamide is a liquid at room temperature, while the other amides are solids.
-For primary amides, the - NH, group can form several hydrogen bonds, which gives primary amides high melting points.
-The melting points of the secondary amides are lower because the number of hydrogen bonds decreases.
-Tertiary amides have even lower melting points because they cannot form hydrogen bonds with other tertiary amides.

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1. Most Amides are colorless and odorless.
2. Amides have comparatively high boiling points and melting points.
3. Lithium Amide is a HIGHLY FLAMMABLE and REACTIVE chemical and a DANGEROUS FIRE and EXPLOSION HAZARD.
4. The small amides are soluble in water because they have the ability to hydrogen bond with the water molecules.
5. Amides are very weak bases.

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1. ThoughtCo.
2. StudySmarter
3. Britannica
4. Chemistry Book, Pearson, Benjamming Cummings, Ninth Edition.